Article
Marine & Freshwater Biology
Ting Yu, Chengzhang Hu, Xiaoyu Zhao, Ling Cai, Bei Chen, Lingcan Lu, Ming Yang
Summary: Increasing evidence suggests that long non-coding RNAs (lncRNAs) play important roles in various biological processes. However, there is little research on the functional roles of lncRNAs in teleost fish. In this study, a novel lncRNA (linc-93.2) was identified in common carp macrophages after exposure to the endocrine disrupting chemical BPA. The results showed that linc-93.2 is involved in the immune and neurological functions of fish.
AQUATIC TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Larken Root, Aurora Campo, Leah MacNiven, Pazit Con, Avner Cnaani, Dietmar Kultz
Summary: The interaction of organisms with their environment is complex and requires the study of genotype to phenotype continuum at multiple levels of organization. Studies of transcriptome and proteome regulation are necessary for better understanding environmental effects on organisms. The application of functional enrichment analyses to DIA assay data sets can identify key elements controlled by environmental factors in organisms.
MOLECULAR ECOLOGY RESOURCES
(2021)
Article
Environmental Sciences
Erin S. McCallum, Daniel Cerveny, Aneesh P. H. Bose, Jerker Fick, Tomas Brodin
Summary: Internal, slow-release implants are a useful method for delivering long-term exposure to pharmaceutical pollutants. In this study, we tested and validated a slow-release implant method using two lipid-based carriers in fish. The carriers released the pollutant, fluoxetine, in different manners, and the highest concentration was found in the brain tissue. By comparing the implants with waterborne exposures, we demonstrated the effectiveness of internal exposures in assessing the impacts of pharmaceutical pollutants in natural environments.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2023)
Review
Clinical Neurology
S. E. Cohen, J. B. Zantvoord, B. N. Wezenberg, J. G. Daams, C. L. H. Bockting, D. Denys, G. A. van Wingen
Summary: This study assessed the accuracy of electroencephalography (EEG) in predicting treatment response in major depressive disorder. The results showed that EEG can accurately predict the response to antidepressant treatment, but further validation studies are needed to develop a clinical tool for guiding interventions in MDD.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Fisheries
Michal Stosik, Beata Tokarz-Deptula, Wieslaw Deptula
Summary: The paper discusses the issue of intestinal mucosa immunity in teleost fish. The organization and functional properties of the elements that determine this immunity are reviewed according to current data. The knowledge of intestinal mucosal immunity in teleost fish has great potential for practical applications in the field of epidemiological safety.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Jarl Bogwald, Roy A. Dalmo
Summary: Oral vaccination is considered a suitable method for mass immunization of large and stress-sensitive fish populations, as it can induce mucosal immunity. By encapsulating antigens and viruses in alginate microspheres and other carriers, oral vaccines can effectively deliver to the intestine.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Behavioral Sciences
Ruxandra F. Sirbulescu, Iulian Ilies, Lisa Amelung, Gunther K. H. Zupanc
Summary: The study found that teleost fish, specifically the brown ghost knifefish, are able to successfully regenerate injured axons and produce new neurons from adult neural stem cells after spinal cord injury. Proteome analysis revealed 42 proteins with significant differences in abundance between injured and intact samples. These proteins are involved in axon development and regeneration, neuronal differentiation and re-establishment of neural connections, neuroprotection, redox homeostasis, membrane repair, and metabolism. Interestingly, proteins related to inflammatory responses were not significantly regulated.
JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY
(2022)
Article
Obstetrics & Gynecology
L. Kolding, V Ehrenstein, L. Pedersen, P. Sandager, O. B. Petersen, N. Uldbjerg, L. H. Pedersen
Summary: The study shows that exposure to venlafaxine is associated with an increased risk of cardiac malformations, but the absolute risk is low. Potential mechanisms include direct effects or confounding by indication. Venlafaxine exposure may serve as a marker for high-risk pregnancies that may benefit from fetal echocardiography.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Article
Obstetrics & Gynecology
Rita Rahban, Anders Rehfeld, Christian Schiffer, Christoph Brenker, Dorte Louise Egeberg Palme, Tao Wang, Johannes Lorenz, Kristian Almstrup, Niels E. Skakkebaek, Timo Struenker, Serge Nef
Summary: The study found that the SSRI antidepressant Sertraline affects human sperm function by inhibiting the sperm-specific Ca2+ channel CatSper, potentially impairing the fertilization process. This was an in vitro study, and further research is needed to assess the physiological relevance in vivo.
HUMAN REPRODUCTION
(2021)
Article
Environmental Sciences
Qingjing Hu, Wanyu Zhao, Keming Qu, Ning An, Lingxiao Li, Yuqiu Wei, Ying Bai, Tao Jiang, Jufa Chen, Fangqun Dai, Hongsheng Wang, Zhengguo Cui
Summary: In this study, the muscle TMAO content of 152 teleost fishes from marginal seas of China and the epipelagic zone of the northwest Pacific Ocean was measured. The results showed significant variations in TMAO content among different species, and species played a more important role than environmental factors in driving TMAO accumulation. Additionally, temperature was identified as a key environmental factor affecting the TMAO content of teleost fishes in shallow seas and the epipelagic zone of the deep ocean.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Zhengyi Fu, Jian G. Qin, Zhenhua Ma, Gang Yu
Summary: This study revealed that acidification of the water environment can cause tissue damage to the head kidney of juvenile L. calcarifer, resulting in significant weakening of immune function. Juvenile L. calcarifer exhibited different coping strategies to different levels of acute acidification stress, but all led to the extensive weakening of head kidney immune function. Through transcriptional analysis, it was found that the response of L. calcarifer head kidney to acidification increased with the severity of acidification level. Additionally, certain immune-related genes were identified to have the most correlation with other genes in the correlation network analysis.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Review
Engineering, Environmental
Sophie L. Gould, Matthew J. Winter, William H. J. Norton, Charles R. Tyler
Summary: Antidepressants, commonly prescribed for psychiatric conditions, may impact fish and other aquatic wildlife when released into the natural environment. However, research suggests that effects on fish at exposure levels occurring in nature are low, particularly for standard measured endpoints in risk assessment. Further studies are needed to assess the risks posed by antidepressants, focusing on behavior, environmentally realistic exposure levels, chronic exposure scenarios, and mixtures analyses.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Medicine, Research & Experimental
Hye In Woo, Jisook Park, Shinn-Won Lim, Doh Kwan Kim, Soo-Youn Lee
Summary: Proteomic analysis revealed changes in transthyretin and TBG levels in MDD patients, which also changed after antidepressant treatment.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Fisheries
Syed Monzur Morshed, Tsung-Han Lee
Summary: The environment has a significant impact on fish as it affects the microbiome and mucosal immunity, which are crucial for their overall health. However, there is a lack of research on the interaction between the microbiome and mucosal immunity under different environmental conditions. This review summarizes the existing literature on the effects of environmental changes, such as temperature, salinity, dissolved oxygen, pH, and photoperiod, on the fish microbiome and mucosal immunity. Understanding the mucosal immunity-microbiome interaction can also enhance aquaculture practices during environmental stress.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Clinical Neurology
Minami Naito, Masaki Kato, Yosuke Koshikawa, Hiroki Bandou, Shiho Sakai, Yoshiteru Takekita, Keiichiro Nishida, Toshihiko Kinoshita
Summary: This study investigated the influence of personality traits on the treatment response to antidepressants in patients with depression. The results showed that neuroticism had a significant impact on treatment outcomes. Depending on the degree of neuroticism, patients had different remission rates when using different antidepressant medications. Therefore, measuring personality traits at the beginning of treatment could help select more appropriate antidepressants and predict the time to remission.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Biophysics
Margarida Coelho, Rohit Mahar, Getachew D. Belew, Alejandra Torres, Cristina Barosa, Fernando Cabral, Ivan Viegas, Amalia Gastaldelli, Vera M. Mendes, Bruno Manadas, John G. Jones, Matthew E. Merritt
Summary: Deuterated water ((H2O)-H-2) is commonly used to trace carbohydrate biosynthesis, but it can distort metabolic information and mediate toxicity. O-18-water ((H2O)-O-18) can be incorporated into specific carbohydrates but has not been evaluated in animal models.
NMR IN BIOMEDICINE
(2023)
Article
Chemistry, Applied
Sandra Lage, Ines I. Afonso, Pedro Reis Costa, Adelino V. M. Canario, Jose P. Da Silva
Summary: TTX and its analogues were found in the tissues of trumpet shell specimens purchased in a market in southern Portugal, suggesting the potential risk of consuming these edible gastropods. Regular monitoring of TTX and analogues in trumpet shell and other edible gastropods is recommended to prevent poisoning incidents.
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
(2023)
Article
Biochemistry & Molecular Biology
Ines Serrenho, Carla M. M. Cardoso, Mario Graos, Alexandra Dinis, Bruno Manadas, Graca Baltazar
Summary: Neonatal hypoxic-ischemic encephalopathy (HIE) is a major cause of death and long-term disability in the perinatal period. Therapeutic hypothermia (HT) is the standard treatment, but its efficacy is limited. Umbilical cord blood cells (UCBC) therapy has been proposed as a potential treatment for neonatal HIE. This study evaluated the effects of UCBC combined with HT and found that the combination therapy improved brain lesions and functional outcomes in neonatal HIE.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemical Research Methods
Tania Lima, Joao Eduardo Rodrigues, Bruno Manadas, Rui Henrique, Margarida Fardilha, Rui Vitorino
Summary: This study reanalyzed a urine proteome dataset from prostate cancer patients and controls using a peptide-centric approach. Compared to the conventional protein-centric approach, the peptide analysis revealed more relevant information related to prostate cancer, highlighting the importance of peptide analysis in proteomics research.
JOURNAL OF PROTEOMICS
(2023)
Article
Horticulture
Melina C. da Silva, Patricia I. S. Pinto, Rui Guerra, Amilcar Duarte, Deborah M. Power, Natalia T. Marques
Summary: This study investigated the transcriptome changes in Citrus macrophylla in response to drought stress and identified thousands of differentially expressed transcripts. The results showed that drought stress can induce the up- and down-regulation of various genes in the stem tissue of Citrus macrophylla, some of which may be associated with drought tolerance in this species.
SCIENTIA HORTICULTURAE
(2023)
Article
Genetics & Heredity
Yu-Qing Wang, Qi Liu, Yan Zhou, Lizhi Chen, Yue-Ming Yang, Xue Shi, Deborah M. Power, Yi-Feng Li
Summary: In this study, transcriptome analysis of different developmental stages of the mussel, Mytilus coruscus, was conducted to uncover the molecular mechanisms underlying larval settlement and metamorphosis. The results showed that highly upregulated differentially expressed genes at the pediveliger stage were enriched in immune-related genes. The findings suggest that the larvae utilize molecules of the immune system to sense and respond to external chemical cues and neuroendocrine signaling pathways. The upregulation of adhesive protein genes linked to byssal thread secretion indicates the anchoring capacity required for larval settlement arises prior to metamorphosis. The results of gene expression support the role of the immune and neuroendocrine systems in mussel metamorphosis and provide a foundation for future studies.
Article
Fisheries
Ana Patricia Mateus, Rita A. Costa, Bastien Sadoul, Marie-Laure Begout, Xavier Cousin, Adelino VM. Canario, Deborah M. Power
Summary: Fish skin is a versatile tissue influenced by epigenetic marks during embryonic development. This study examined the effects of egg incubation temperature on the regeneration of skin wounds in juvenile European sea bass. Results showed that fish from eggs incubated at higher temperatures immediately up-regulated the expression of pcna gene after skin damage, while fish from eggs incubated at lower temperatures up-regulated the expression of krt2 gene one day after damage. Regenerated epidermis was thinner in fish from eggs incubated at lower temperatures, with fewer goblet cells and melanomacrophages. Overall, thermal imprinting of eggs altered the damage-repair response in juvenile sea bass skin.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Catia Pereira, Ander Castander-Olarieta, Itziar A. Montalban, Vera M. Mendes, Sandra Correia, Ana Pedrosa, Bruno Manadas, Paloma Moncalean, Jorge Canhoto
Summary: Understanding the physiological and molecular adjustments during tree stress response is crucial for forest management and breeding programs. Somatic embryogenesis serves as a model to study stress response mechanisms. Heat stress during somatic embryogenesis promotes plant resilience and affects protein production, metabolism regulation, cell division, and amino acid concentrations.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Beatriz Caramelo, Tamaeh Monteiro-Alfredo, Joao Martins, Jose Sereno, Joao Castelhano, Bruno Manadas, Miguel Castelo-Branco, Paulo Matafome
Summary: Functional MRI (fMRI) with H-1-MRS was used to study the neurometabolic changes in animal models of obesity and type 2 diabetes. Rats on a high-fat diet showed elevated levels of NAAG and GSH in the hippocampus, whereas diabetic rats showed elevated levels of taurine and GABA(A)R in the visual cortex. These findings suggest different mechanisms and responses to metabolic and vascular insults in different brain regions.
JOURNAL OF NEUROCHEMISTRY
(2023)
Review
Pediatrics
Ines Caramelo, Margarida Coelho, Miguel Rosado, Carla M. P. Cardoso, Alexandra Dinis, Carlos B. B. Duarte, Mario Graos, Bruno Manadas
Summary: This systematic review identified potential molecules that can be used in the diagnosis of hypoxic-ischemic encephalopathy in daily clinical practice. Increased serum levels of neuron-specific enolase and S100-calcium-binding protein-B were associated with a worse prognosis in newborns that suffered from perinatal asphyxia.
WORLD JOURNAL OF PEDIATRICS
(2023)
Article
Plant Sciences
Susana A. Dandlen, Jose P. Da Silva, Maria Graca Miguel, Amilcar Duarte, Deborah M. Power, Natalia Tomas Marques
Summary: The susceptibility of Citrus macrophylla (CM) to the severe Citrus tristeza virus (CTV), T36, is higher than that of Citrus aurantium (CA). The impact of host-virus interactions on host physiology remains largely unknown. This study evaluated the metabolite profile and antioxidant activity in the phloem sap of healthy and infected CA and CM plants. The results showed that the antioxidant enzyme activity increased significantly in infected CM plants and decreased in infected CA plants. Furthermore, CTV infection resulted in a drastic reduction in secondary metabolites in CA but not in CM.
Editorial Material
Fisheries
Maria Dulce Estevao
Article
Biochemistry & Molecular Biology
Rita I. Pacheco, Maria I. Cristo, Sandra I. Anjo, Andreia F. Silva, Maria Ines Sousa, Renata S. Tavares, Ana Paula Sousa, Teresa Almeida Santos, Mariana Moura-Ramos, Francisco Caramelo, Bruno Manadas, Joao Ramalho-Santos, Sandra Gomes Amaral
Summary: The global trend of rising (male) infertility is concerning. This study aimed to understand unknown origin male infertility (UOMI) by evaluating the male gamete. The study found that idiopathic (ID) patients had the worst sperm functional profile, while unexplained male infertility (UMI) patients were similar to controls. Proteomic analysis identified several differentially expressed proteins in ID and UMI samples. SACA4 and LAMB2 were identified as potential biomarkers for distinguishing ID and UMI patients.
Article
Cell & Tissue Engineering
Ana Marote, Diogo Santos, Barbara Mendes-Pinheiro, Claudia Serre-Miranda, Sandra Anjo, Joana Vieira, Filipa Ferreira-Antunes, Joana Sofia Correia, Caroline Borges-Pereira, Andreia G. Pinho, Jonas Campos, Bruno Manadas, Manuel R. Teixeira, Margarida Correia-Neves, Luisa Pinto, Pedro M. Costa, Laurent Roybon, Antonio J. Salgado
Summary: This study compared the secretomes of long-term cultured BM-MSCs and iMSCs, and conducted a comprehensive characterization of both sources. The results showed that although there were significant differences in proliferation between the two sources, the secretome composition of both sources was similar in pre-senescent and senescent states. These findings suggest that shifting from BM-MSCs to a more advantageous source like iMSCs may yield similar therapeutic effects as the gold-standard MSC source.
STEM CELL REVIEWS AND REPORTS
(2023)
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)