A hypothalamic pathway for Augmentor α–controlled body weight regulation

Transcriptome-wide association study identifies multiple genes associated with childhood body mass index

(2021) Shi Yao et al.   INTERNATIONAL JOURNAL OF OBESITY

Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling

(2021) Hadar Israeli et al.   SCIENCE

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

Structural basis of cytokine-mediated activation of ALK family receptors

(2021) Steven De Munck et al.   NATURE

Mechanism for the activation of the anaplastic lymphoma kinase receptor

(2021) Andrey V. Reshetnyak et al.   NATURE

Structural basis for ligand reception by anaplastic lymphoma kinase

(2021) Tongqing Li et al.   NATURE

Identification of ALK in Thinness

(2020) Michael Orthofer et al.   CELL

Molecular design of hypothalamus development

(2020) Roman A. Romanov et al.   NATURE

Identification of the MC4R start lost mutation in a morbidly obese Brazilian patient

(2019) Ana Carolina Proença Fonseca et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Genetic architecture of human thinness compared to severe obesity

(2019) Fernando Riveros-McKay et al.   PLoS Genetics

Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity

(2019) Luca A. Lotta et al.   CELL

Role and targeting of anaplastic lymphoma kinase in cancer

(2018) Carminia Maria Della Corte et al.   Molecular Cancer

ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells

(2018) Andrey Fadeev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a biologically active fragment of ALK and LTK-Ligand 2 (augmentor-α)

(2018) Andrey V. Reshetnyak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A molecular census of arcuate hypothalamus and median eminence cell types

(2017) John N Campbell et al.   NATURE NEUROSCIENCE

Alk and Ltk ligands are essential for iridophore development in zebrafish mediated by the receptor tyrosine kinase Ltk

(2017) Elizabeth S. Mo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand–receptor interactions

(2015) Andrey V. Reshetnyak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase

(2015) Jikui Guan et al.   eLife

Cell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-loss

(2015) Fredrick E Henry et al.   eLife

Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome

(2014) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL