Antibody homotypic interactions are encoded by germline light chain complementarity determining region 2

Structural insights into immunoglobulin M

(2020) Yaxin Li et al.   SCIENCE

Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab

(2020) Lionel Rougé et al.   SCIENCE

Dual Epitope Targeting and Enhanced Hexamerization by DR5 Antibodies as a Novel Approach to Induce Potent Antitumor Activity Through DR5 Agonism

(2020) Marije B. Overdijk et al.   MOLECULAR CANCER THERAPEUTICS

Enhanced SARS-CoV-2 neutralization by dimeric IgA

(2020) Zijun Wang et al.   Science Translational Medicine

Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11

(2020) Iga Kucharska et al.   eLife

High frequency of shared clonotypes in human B cell receptor repertoires

(2019) Cinque Soto et al.   NATURE

Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members

(2019) Yanli Yang et al.   mAbs

Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope

(2018) Katharina Imkeller et al.   SCIENCE

Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab

(2018) S. Michael Chin et al.   Nature Communications

Cryo-EM structure of P. falciparum circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts

(2018) David Oyen et al.   Science Advances

Fc Engineering Approaches to Enhance the Agonism and Effector Functions of an Anti-OX40 Antibody

(2016) Di Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRAIL-R2 Superoligomerization Induced by Human Monoclonal Agonistic Antibody KMTR2

(2015) Taro Tamada et al.   Scientific Reports

Restricted Diversity of Antigen Binding Residues of Antibodies Revealed by Computational Alanine Scanning of 227 Antibody–Antigen Complexes

(2014) Gautier Robin et al.   JOURNAL OF MOLECULAR BIOLOGY

Complement Is Activated by IgG Hexamers Assembled at the Cell Surface

(2014) C. A. Diebolder et al.   SCIENCE

Antibody and Antigen Contact Residues Define Epitope and Paratope Size and Structure

(2013) J. W. Stave et al.   JOURNAL OF IMMUNOLOGY

IgBLAST: an immunoglobulin variable domain sequence analysis tool

(2013) Jian Ye et al.   NUCLEIC ACIDS RESEARCH

Structural Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-Recognizing Antibody 2G12

(2013) Yunji Wu et al.   Cell Reports

A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency

(2012) M Chodorge et al.   CELL DEATH AND DIFFERENTIATION