Ponicidin suppresses pancreatic cancer growth by inducing ferroptosis: Insight gained by mass spectrometry-based metabolomics

An Insight into the Anti-Angiogenic and Anti-Metastatic Effects of Oridonin: Current Knowledge and Future Potential

(2021) Nurul Akmaryanti Abdullah et al.   MOLECULES

Lipid Metabolism and Ferroptosis

(2021) Ji-Yoon Lee et al.   Biology-Basel

Shuganning injection, a traditional Chinese patent medicine, induces ferroptosis and suppresses tumor growth in triple-negative breast cancer cells

(2021) Jingjing Du et al.   PHYTOMEDICINE

Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer

(2021) Ying Liu et al.   Acta Pharmaceutica Sinica B

Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols

(2021) Max Sauerland et al.   FREE RADICAL BIOLOGY AND MEDICINE

Involvement of Glutathione Depletion in Selective Cytotoxicity of Oridonin to p53-Mutant Esophageal Squamous Carcinoma Cells

(2020) Yinchao Li et al.   Frontiers in Oncology

Sesamin induces A549 cell mitophagy and mitochondrial apoptosis via a reactive oxygen species-mediated reduction in mitochondrial membrane potential

(2020) Shasha Yang et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

xCT Inhibition Increases Sensitivity to Vorinostat in a ROS-Dependent Manner

(2020) Keiko Miyamoto et al.   Cancers

BAX-dependent mitochondrial pathway mediates the crosstalk between ferroptosis and apoptosis

(2020) Young-Sun Lee et al.   APOPTOSIS

Pancreatic cancer

(2020) Jonathan D Mizrahi et al.   LANCET

OP16 induces deadly autophagy and apoptosis of cells by inhibiting Akt in esophageal squamous cell carcinoma

(2020) Guiqin Hou et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Oridonin induces ferroptosis by inhibiting gamma‐glutamyl cycle in TE1 cells

(2020) Junhong Zhang et al.   PHYTOTHERAPY RESEARCH

Glutathione S-Transferase Mu-3 Predicts a Better Prognosis and Inhibits Malignant Behavior and Glycolysis in Pancreatic Cancer

(2020) Shunda Wang et al.   Frontiers in Oncology

Oxidative Damage and Antioxidant Defense in Ferroptosis

(2020) Feimei Kuang et al.   Frontiers in Cell and Developmental Biology

Metabolite profiles of Pulicaria crispa and P. incisa in relation to their in-vitro/ in-vivo antioxidant activity and hepatoprotective effect: A comparative mass spectrometry-based metabolomics

(2020) Osama A. El-Sabagh et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1

(2019) Hironari Nishizawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Danshen Improves Survival of Patients With Breast Cancer and Dihydroisotanshinone I Induces Ferroptosis and Apoptosis of Breast Cancer Cells

(2019) Yu-Shih Lin et al.   Frontiers in Pharmacology

Acute pancreatitis as an early marker of pancreatic cancer and cancer stage, treatment, and prognosis

(2019) Jakob Kirkegård et al.   Cancer Epidemiology

Comprehensive Strategy to Construct In-House Database for Accurate and Batch Identification of Small Molecular Metabolites

(2018) Xinjie Zhao et al.   ANALYTICAL CHEMISTRY

An emerging strategy for evaluating the grades of Keemun black tea by combinatory liquid chromatography-Orbitrap mass spectrometry-based untargeted metabolomics and inhibition effects on α-glucosidase and α-amylase

(2018) Xuemei Guo et al.   FOOD CHEMISTRY

CavityPlus: a web server for protein cavity detection with pharmacophore modelling, allosteric site identification and covalent ligand binding ability prediction

(2018) Youjun Xu et al.   NUCLEIC ACIDS RESEARCH

Ponicidin inhibits pro-inflammatory cytokine TNF-α-induced epithelial–mesenchymal transition and metastasis of colorectal cancer cells via suppressing the AKT/GSK-3β/Snail pathway

(2018) Zhengguang Zhang et al.   INFLAMMOPHARMACOLOGY

Dihomo-γ-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA

(2018) Xiaoyu Yang et al.   Redox Biology

GSH depletion and consequent AKT inhibition contribute to the Nrf2 knockdown-induced decrease in proliferation in glioblastoma U251 cells

(2017) Yue Jia et al.   ONCOLOGY REPORTS

Fatty Acid–Mediated Stromal Reprogramming of Pancreatic Stellate Cells Induces Inflammation and Fibrosis That Fuels Pancreatic Cancer

(2017) Tomoki Hata et al.   PANCREAS

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Motions of Allosteric and Orthosteric Ligand-Binding Sites in Proteins are Highly Correlated

(2016) Xiaomin Ma et al.   Journal of Chemical Information and Modeling

Intracellular Glutathione Depletion by Oridonin Leads to Apoptosis in Hepatic Stellate Cells

(2014) Liang-Mou Kuo et al.   MOLECULES

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL