Article
Chemistry, Multidisciplinary
Clare L. Higgins, Sorin V. Filip, Ashfaq Afsar, Howard M. Colquhoun, Wayne Hayes
Summary: Taking inspiration from the food industry, an assay was developed to test the efficiency of new phenolic antioxidants by spectrophotometric measurement of the stable free radical DPPH. The kinetics of the reaction were categorized as fast, medium, or slow based on the disappearance of the absorbance band. The study also analyzed the stoichiometry of the radical scavenging reaction and its relationship with the structure-activity of phenolic antioxidants.
Article
Food Science & Technology
Miwa Takatsuka, Satoru Goto, Kenshiro Kobayashi, Yuta Otsuka, Yohsuke Shimada
Summary: This study investigated the radical scavenging reaction of antioxidants in DPPH and ABTS assays using ESR and developed an analytical method. The results demonstrated that the first component in both assays contributed significantly to the radical scavenging reaction.
Article
Environmental Sciences
Muhammad Waseem, Awais Ahmad, Muhammad Sagir, Umer Younas, Zohaib Saeed, Muhammad Pervaiz, Faisal Ali, Ahmed Muteb Aljuwayid, Mohamed A. Habila, Rama Rao Karri
Summary: A novel nanocomposite V2O5/TiO2/g-C3N4 was synthesized by a simple hydrothermal method, which exhibited excellent scavenging of free radicals and photocatalytic ability for dye degradation, indicating its potential for environmental remediation.
ENVIRONMENTAL RESEARCH
(2023)
Article
Food Science & Technology
Mauro Gisbert, Andrea Aleixandre, Jorge Sineiro, Cristina M. Rosell, Ramon Moreira
Summary: This paper studied the effect of blending procedures between seaweed flour and corn starch on the interactions between polyphenols and starch. It found that different blending methods resulted in different interactions and enhanced the retention of polyphenols, achieving starchy foods with high bioactivity.
Article
Polymer Science
Smaher M. Elbayomi, Haili Wang, Tamer M. Tamer, Yezi You
Summary: The study synthesized an aromatic alginate derivative with benzoyl groups, which exhibited higher thermal stability, anti-inflammatory properties, and enhanced antioxidant activity compared to regular alginate, indicating its potential for use in gene and drug delivery applications.
Article
Plant Sciences
Jae Il Lyu, Jaihyunk Ryu, Kyoung-Sun Seo, Kyung-Yun Kang, Sang Hoon Park, Tae Hyun Ha, Joon-Woo Ahn, Si-Yong Kang
Summary: In this study, the phenolic compounds in hop strobile extracts were investigated, and their antioxidant property was evaluated. The results showed that the type of extraction solvent used significantly affected the phenolic compounds and antioxidant activity.
Review
Biochemistry & Molecular Biology
Nuri Gueven, Pranathi Ravishankar, Rajaraman Eri, Emma Rybalka
Summary: Idebenone is widely described as an antioxidant drug, but there is a significant discrepancy between its pharmacokinetics and achievable tissue levels in target tissues, casting doubt on our current understanding. A new framework has been proposed based on recent discoveries to explain its mode of action, providing a rational approach for testing its effects in novel indications.
Article
Chemistry, Physical
Dinh Quy Huong, Mai Van Bay, Pham Cam Nam
Summary: The antioxidant abilities of thiourea derivatives were characterized by measuring the color change of DPPH and ABTS when reacting with the compounds. DPTU exhibited better free radical capture capability compared to BPTU, which was confirmed by quantum chemical calculations. Kinetic calculations revealed that hydrogen atom transfer mechanism is preferred over single electron transfer mechanism when thiourea derivatives react with free radicals, with HAT mechanism accounting for 99.99% of the product amount.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Biochemistry & Molecular Biology
Min Woo Baek, Han Ryul Choi, Tifsehit Solomon, Cheon Soon Jeong, Ok-Hwan Lee, Shimeles Tilahun
Summary: The research findings demonstrate that preharvest MeJA treatment can significantly enhance the phytochemical composition and antioxidant activities of hydroponically grown pak choi. Hydroponically grown MeJA-treated pak choi shows higher levels of chlorophylls, total phenolics, GSLs, total flavonoids, and stronger antioxidant capacities compared to soil-grown counterparts.
Article
Food Science & Technology
Rosanna Ginocchio, Eduardo Munoz-Carvajal, Patricia Velasquez, Ady Giordano, Gloria Montenegro, German Colque-Perez, Cesar Saez-Navarrete
Summary: The seed oil of the Mayten tree has potential health benefits due to its high levels of monounsaturated and polyunsaturated fatty acids, as well as antioxidant compounds.
Review
Physics, Mathematical
Demetrios Christodoulou
Summary: This study aimed to evaluate the free radical scavenging abilities of Tectaria paradoxa and Bolbitis appendiculata using various assays. The results showed that the methanolic extracts of both plants exhibited the highest antioxidant activity, with acetone extracts demonstrating the best DPPH scavenging ability. SOD scavenging ability was also observed in the extracts, with petroleum ether and acetone extracts showing the highest activity.
JOURNAL OF MATHEMATICAL PHYSICS
(2022)
Article
Horticulture
Nicole Melanie Falla, Sonia Demasi, Matteo Caser, Valentina Scariot
Summary: Tea, a hot beverage made from dried leaves of the Camellia sinensis plant, is widely consumed globally and appreciated for its aroma, taste, and health benefits. This research evaluated the bioactive compounds and antioxidant activity of two green teas produced in Italy, showing that Italy has the potential to profitably cultivate Camellia sinensis.
Article
Engineering, Chemical
Kacper Kut, Bogumil Cieniek, Ireneusz Stefaniuk, Grzegorz Bartosz, Izabela Sadowska-Bartosz
Summary: This article presents a modification of the ABTS(center dot) decolorization assay for plate readers. The modification involves adding an antioxidant to the ABTS solution, resulting in decreased absorbance. The antioxidant activities are compared based on the kinetic assay of absorbance decrease, concentration dependence of absorbance decrease, and area under curve. The study distinguishes fast and slow antioxidants based on their reaction time.
Article
Biochemistry & Molecular Biology
Janez Mravljak, Lara Slavec, Martina Hrast, Matej Sova
Summary: Quinazolinones display diverse biological activities in medicinal chemistry. The study synthesized two series of 2-substituted quinazolin-4(3H)-ones and evaluated their antioxidant properties using three methods. The presence of hydroxyl groups or an ethylene linker enhanced antioxidant activity and led to metal-chelating properties in some derivatives.
Article
Biochemistry & Molecular Biology
Ali Osman, Ali Salama, Kamal Emam Mahmoud, Mahmoud Sitohy
Summary: Phycocyanin extracted from Anabaena biomass showed high antioxidant activity against DPPH and ABTS free radicals, with potential hepatoprotective effects in Albino rats exposed to CCl4-induced oxidative stress. The findings suggest that phycocyanin could serve as a natural antioxidant with beneficial applications in food and health industries.
JOURNAL OF FOOD BIOCHEMISTRY
(2021)
Article
Environmental Sciences
Sonia Pedreiro, Sandrine da Ressurreicao, Maria Lopes, Maria Teresa Cruz, Teresa Batista, Artur Figueirinha, Fernando Ramos
Summary: Crepis vesicaria subsp. taraxacifolia leaves are rich in carbohydrates, minerals, proteins and lipids, with chicoric acid as the major phenolic constituent. The extract exhibited strong antioxidant and anti-inflammatory properties, with low cytotoxicity towards cells.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Agronomy
Touka Letaief, Jamel Mejri, Sandrine Ressureicao, Manef Abderrabba, Rui Costa
Summary: The study analyzed the chemical composition and rheological properties of Ziziphus lotus fruit syrups prepared using traditional and enzymatic methods, finding them to be potential energy sources with different flow behaviors at varying concentrations. The research suggests that these syrups have potential for commercial development.
INTERNATIONAL AGROPHYSICS
(2021)
Article
Chemistry, Medicinal
Martin Vojtek, Salome Goncalves-Monteiro, Edgar Pinto, Sara Kalivodova, Agostinho Almeida, Maria P. M. Marques, Ana L. M. Batista de Carvalho, Clara B. Martins, Helder Mota-Filipe, Isabel M. P. L. V. O. Ferreira, Carmen Diniz
Summary: This study assessed the pharmacokinetics and biodistribution of a dinuclear palladium(II)-spermine chelate (Pd(2)Spm) in mice, showing promising characteristics for its potential use as an anticancer agent. Palladium exhibited biphasic kinetics in serum, with high tissue distribution including in the kidney, liver, lungs, ovaries, adipose tissue, and mammary glands. These findings suggest Pd(2)Spm may be a promising pharmacological agent for cancer treatment.
Article
Biotechnology & Applied Microbiology
C. B. Martins, O. Ferreira, T. Rosado, E. Gallardo, S. Silvestre, L. M. A. Santos
Summary: The study evaluated the potential pharmaceutical interest of extracts from three eustigmatophyte strains and found that C. aquilonaris exhibited the highest antioxidant activity, selective antiproliferative effect, and higher pigment and phenolic content. These three ACOI eustigmatophytes show promise for applications in improving human health, particularly in cancer prevention and treatment.
BIOTECHNOLOGY LETTERS
(2021)
Article
Chemistry, Medicinal
Virginio Cepas, Ignacio Gutierrez-Del-Rio, Yuly Lopez, Saul Redondo-Blanco, Yaiza Gabasa, Maria Jose Iglesias, Raquel Soengas, Andres Fernandez-Lorenzo, Sara Lopez-Ibanez, Claudio J. Villar, Clara B. Martins, Joana D. Ferreira, Mariana F. G. Assuncao, Lilia M. A. Santos, Joao Morais, Raquel Castelo-Branco, Mariana A. Reis, Vitor Vasconcelos, Fernando Lopez-Ortiz, Felipe Lombo, Sara M. Soto
Summary: The study discusses the isolation, structural elucidation, and antibiotic and antibiofilm activities of diverse lipids produced by microalgae and cyanobacteria strains from two European collections. Different active sub-fractions were identified, including sulfoquinovosyldiacylglycerol, monogalactosylmonoacylglycerol, and alpha-linolenic acid, among others. These lipids show potential for clinical treatments as alternative or complementary therapies to antibiotics.
Article
Chemistry, Medicinal
Diana Pacheco, Joao Cotas, Andreia Domingues, Sandrine Ressurreicao, Kiril Bahcevandziev, Leonel Pereira
Summary: Red seaweed Chondracanthus teedei var. lusitanicus is a potential nutraceutical source with high mineral and carbohydrate content, despite low levels of calcium and phosphorus. Its high nitrogen and potassium content makes it an interesting option for supplementing human diet with promising nutraceutical properties.
Article
Oncology
Ines P. Santos, Clara B. Martins, Luis A. E. Batista de Carvalho, Maria P. M. Marques, Ana L. M. Batista de Carvalho
Summary: This study utilizes spectroscopy methods to identify specific biomarkers of malignancy in several types of human breast cancer cells, enabling accurate discrimination between different types of breast cancer.
Article
Biochemistry & Molecular Biology
Sandrine Da Ressurreicao, Sonia Pedreiro, Maria Teresa Batista, Artur Figueirinha
Summary: This study found that polyphenolic compounds from Cymbopogon citratus can prevent the absorption of cholesterol in the gut by destroying the micellar structure. This contributes to their cholesterol-lowering activity.
Article
Biochemistry & Molecular Biology
Raquel C. C. Laginha, Clara B. B. Martins, Ana L. C. Brandao, Joana Marques, M. Paula M. Marques, Luis A. E. Batista de Carvalho, Ines P. Santos, Ana L. M. Batista de Carvalho
Summary: In this study, the cytotoxic effects of a complex with two Pd(II) centers (Pd(2)Spm) on healthy and cancerous prostate human cell lines were evaluated and compared to cisplatin. Fourier Transform Infrared (FTIR) and Raman microspectroscopies were used to understand the molecular mechanisms of action of both drugs, revealing differences in their impact on DNA, lipids, and proteins.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Jessica D. Silva, Joana Marques, Ines P. Santos, Ana L. M. Batista de Carvalho, Clara B. Martins, Raquel C. Laginha, Luis A. E. Batista de Carvalho, Maria Paula M. Marques
Summary: A dinuclear Pt(II) complex with putrescine as bridging polyamine ligand was synthesized and evaluated for its potential anticancer activity against a human non-small cell lung cancer line, as well as non-cancer cells. In vitro cytotoxicity assays, microFTIR, and microRaman spectroscopies were used to assess the effect of the complex. The complex showed a major impact on cellular proteins and lipids in cancer cells, while exhibiting lower toxicity towards non-malignant cells.
Article
Chemistry, Multidisciplinary
Maria Joao Barroca, Catarina Flores, Sandrine Ressurreicao, Raquel Guine, Nadia Osorio, Aida Moreira da Silva
Summary: Excessive sodium intake has been linked to non-communicable diseases such as hypertension, cardiovascular disease, and stroke. Bread is a major dietary source of sodium, and incorporating salty taste halophyte powder could be a promising strategy to reduce salt content in bread.
APPLIED SCIENCES-BASEL
(2023)
Article
Pharmacology & Pharmacy
Martin Vojtek, Clara B. Martins, Raquel Ramos, Sara Gomes Duarte, Isabel M. P. L. V. O. Ferreira, Ana L. M. Batista de Carvalho, M. Paula M. Marques, Carmen Diniz
Summary: Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer and current drug treatments often face limitations. In this study, Pd(3)Spd(2) was found to be a promising metal-based anticancer agent for TNBC treatment, surpassing its Pt analog in activity. Pd(3)Spd(2) demonstrated similar antiproliferative activity in both sensitive and resistant TNBC cells and showed a promising selectivity index ratio, indicating its potential for further exploration in treating TNBC and its cisplatin-resistant forms.
Proceedings Paper
Agriculture, Multidisciplinary
R. L. Pato, G. Botelho, J. Franco, S. Santos, S. Ressurreicao, P. Figueiredo, J. Gama, F. Gomes
Summary: The study results show that planting clones adapted to the agroforest system conditions, through fertilization and preserving soil organic layers, contributes to the sustainability, fruit quality, and production of the agroforest system.
IX INTERNATIONAL SYMPOSIUM ON MINERAL NUTRITION OF FRUIT CROPS
(2022)
Article
Chemistry, Physical
M. P. M. Marques, I. P. Santos, A. L. M. Batista de Carvalho, A. P. Mamede, C. B. Martins, P. Figueiredo, M. Sarter, V. Garcia Sakai, L. A. E. Batista de Carvalho
Summary: This study used quasi-elastic neutron scattering to investigate the dynamical behavior of water in human cancer specimens and surrounding normal tissue. The results revealed different dynamics between malignant and non-malignant specimens, with breast tissue showing higher plasticity and tongue tissue showing an opposite effect. The findings provide insights into the cellular biomechanical properties associated with normal-to-malignant transformation.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Arona Pires, Silvia Agreira, Sandrine Ressurreicao, Joana Marques, Raquel Guine, Maria Joao Barroca, Aida Moreira da Silva
Summary: Halophyte plant sea purslane has significant nutritional and antioxidant properties, making it a potential source of dietary fiber, protein, and natural minerals. The plant's methanolic extracts can be used in food products, highlighting its potential as a salt substitute.
APPLIED SCIENCES-BASEL
(2021)
