Article
Agronomy
Haiyue Yu, Yubin Wang, Jiapeng Xing, Yushi Zhang, Liusheng Duan, Mingcai Zhang, Zhaohu Li
Summary: The study investigates the role of Coronatine (COR) in counteracting drought stress by modulating reactive oxygen species (ROS) homeostasis, water balance, and antioxidant regulation in detached maize plants. COR decreases water loss rate and increases ROS production, while antioxidants eliminate the effect of water loss and decrease ROS production induced by COR. The results suggest that COR can improve maize performance under drought stress by modulating ROS homeostasis to maintain water loss rate and antioxidant enzyme activities.
Review
Chemistry, Multidisciplinary
Chenyang Zhang, Xin Wang, Jiangfeng Du, Zhanjun Gu, Yuliang Zhao
Summary: ROS play a vital role in physiological and pathological processes, and research on regulating ROS for disease treatments has gained wide attention. Advances in nanotechnology have led to the development of numerous nanomaterials with the ability to regulate ROS, aiming to find new and effective ROS-related nanotherapeutic modalities. Despite significant progress in ROS-based nanomedicines, there is a need to address fundamental principles for designing ROS-associated nanomedicines to minimize gaps in biomedical applications. This review summarizes current progress in ROS-associated nanomedicines in disease treatments and presents key principles for their design. Future perspectives in the development of ROS-associated nanomedicines are also discussed.
Review
Chemistry, Inorganic & Nuclear
Nahyun Kwon, Dayeh Kim, K. M. K. Swamy, Juyoung Yoon
Summary: Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play crucial roles in human life, but overproduction can lead to cell damage and diseases. Researchers have developed fluorescent and luminescent probes based on metal-coordinated systems to detect and image these active species, providing valuable tools for studying their roles in signaling and pathology.
COORDINATION CHEMISTRY REVIEWS
(2021)
Review
Biotechnology & Applied Microbiology
Jiaxue Liu, Boyan Jia, Zhibo Li, Wenliang Li
Summary: Applying reactive polymer materials sensitive to biological stimuli has attracted extensive research interest. The application of reactive oxygen species (ROS)-responsive polymers as drug-delivery systems in organisms has received much attention due to the special physiological effects of ROS on tumors or inflammation. The research progress of ROS-responsive polymers and their application in recent years were summarized and analyzed in this paper. From the perspective of nanoparticle drug delivery systems, multi-responsive delivery systems, and ROS-responsive hydrogels, the future development trends in this field were discussed.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Byulhana Kim, Young Kim, Yoonho Lee, Joomin Oh, Youngmee Jung, Won-Gun Koh, Justin J. Chung
Summary: Chronic wounds are difficult to repair due to continuous inflammatory response, which inhibits the normal wound healing mechanism. An antioxidant hydrogel has been developed to scavenge reactive oxygen species (ROS) and promote chronic wound healing.
MACROMOLECULAR BIOSCIENCE
(2022)
Article
Environmental Sciences
Prabhakar Singh, Sakshi Singh, Priyanka Maurya, Abhishek Mohanta, Hardik Dubey, Sk. Riyazat Khadim, Ankit K. Singh, Adarsh K. Pandey, Arvind K. Singh, Ravi K. Asthana
Summary: Selenium is an essential element for living systems, but becomes toxic at higher concentrations. This study exposed Dunaliella salina cells to different selenium concentrations and found that 50 mg/L selenium had no significant effect on cell growth and selenium accumulation. However, higher selenium levels led to a decrease in photosynthetic efficiency, chlorophyll content, and an increase in reactive oxygen species, proline content, and lipid peroxidation. Superoxide dismutase and catalase played important roles in antioxidative defense. The accumulation of carotenoids varied at different selenium concentrations, and exposure to 200 mg/L selenium resulted in organelle disorganization. Therefore, the selenium-enriched biomass obtained at 50 mg/L could be used for biofortification of food and feed.
MARINE POLLUTION BULLETIN
(2023)
Article
Plant Sciences
Rajesh Kumar Tewari, Namita Yadav, Roshani Gupta, Praveen Kumar
Summary: Mineral nutrients are essential for plant growth and development, with deficiencies leading to increased production of reactive oxygen species and oxidative stress. Plants have developed enzymatic and non-enzymatic antioxidant scavenging systems to protect against damage caused by reactive oxygen species.
JOURNAL OF SOIL SCIENCE AND PLANT NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Aleksandra Jankovic, Andjelika Kalezic, Aleksandra Korac, Biljana Buzadzic, Kenneth B. Storey, Bato Korac
Summary: This article discusses how hibernating animals survive by utilizing adaptive responses such as lowering body temperature and metabolic suppression, and how their tissues and organs sustain no damage during hibernation. Discovering the molecular mechanisms behind these hibernation processes can provide insights not only into hibernation itself, but also into complex medical conditions and overcoming limitations in space travel.
ANTIOXIDANTS & REDOX SIGNALING
(2023)
Review
Chemistry, Multidisciplinary
Gabriel T. Huynh, Vidhishri Kesarwani, Julia A. Walker, Jessica E. Frith, Laurence Meagher, Simon R. Corrie
Summary: The combination of nanomaterials and fluorescent detection offers new opportunities for monitoring oxygen and ROS in biological systems, improving optical properties and interactions with cells and media, and providing ratiometric sensing robust to environmental drift.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Physical
Patryk Szymaszek, Patrycja Sroda, Malgorzata Tyszka-Czochara, Anna Chachaj-Brekiesz, Tomasz Swiergosz, Joanna Ortyl
Summary: Here we report the synthesis of a novel fluorescent probe P182 for quantitative measurement of H2O2. This fluorometric probe displays a fluorescence turn-on response in the presence of H2O2. It offers good performances in terms of sensitivity and response time, and shows non-toxic activity for in vivo studies. This study provides research on molecular fluorescence probe for the detection of H2O2.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Review
Biochemistry & Molecular Biology
Aikaterini Berdiaki, Monica Neagu, Ioanna Spyridaki, Andrey Kuskov, Serge Perez, Dragana Nikitovic
Summary: Hyaluronan (HA) is a natural compound that is found on the cell surface and tissue extracellular matrix. It is synthesized by enzymes and degraded by other substances. HA has different effects on the body depending on its molecular weight, with high molecular weight HA being anti-inflammatory and low molecular weight HA being pro-inflammatory. Reactive oxygen species (ROS) can degrade HA and affect vascular integrity, while HA can also play a role in wound healing. Understanding the interactions between ROS and HA is an important research topic.
Article
Agronomy
Saman Zahra, Sibgha Noreen, Rafia Abid, Ahmed Akram, Seema Mahmood, Tariq Shah, Abdulaziz Abdulla Alsahli
Summary: The growth potential of three minor fruit species after exposure to different nickel levels was evaluated. The results showed that nickel exposure negatively affected biomass elongation and caused oxidative damage. However, one of the species exhibited resilience through restricted nickel transfer, adequate nutrient uptake, and enhanced antioxidant enzyme biosynthesis.
Article
Biotechnology & Applied Microbiology
L. A. Pagnussat, M. Do Nascimento, G. Maroniche, G. Gonorazky, L. Sanchez Rizza, C. Creus, L. Curatti
Summary: There is a growing interest in using microalgae for various purposes, but the availability of suitable water often compromises biomass productivity. This study aimed to analyze if inoculation with a plant growth-promoting bacterium could improve the growth of microalgae under salt stress.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2023)
Article
Biochemistry & Molecular Biology
Chih-Hsing Hung, Yi-Ching Lin, Yi-Giien Tsai, Yu-Chih Lin, Chia-Hong Kuo, Mei-Lan Tsai, Chao-Hung Kuo, Wei-Ting Liao
Summary: Acrylamide promoted mitochondria-specific ROS generation, increased gene expression of mitochondrial respiratory chain complex II SDHA, induced histone modifications and upregulated PINK1 expression, leading to a macrophage M2 polarization shift in THP-1 cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Medicinal
Okhil K. Nag, Jawad Naciri, Kwahun Lee, Eunkeu Oh, Bethany Almeida, James B. Delehanty
Summary: In this study, a liquid crystal nanoparticle (LCNP) conjugate system was developed to enhance the cellular uptake and scavenging activity against reactive oxygen species (ROS) by combining the antioxidant TEMPO with the LCNP. The results showed that the TEMPO-conjugated LCNP effectively reduced ROS activity and lipid peroxidation in live cells, suggesting its potential in protecting cells from oxidative stress.