标题
Oridonin alleviates hyperbilirubinemia through activating LXRα-UGT1A1 axis
作者
关键词
Hyperbilirubinemia, Oridonin, LXRα, UGT1A1, Bilirubin
出版物
PHARMACOLOGICAL RESEARCH
Volume 178, Issue -, Pages 106188
出版商
Elsevier BV
发表日期
2022-03-22
DOI
10.1016/j.phrs.2022.106188
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Hepatoprotective effects of oridonin against bisphenol A induced liver injury in rats via inhibiting the activity of xanthione oxidase
- (2021) Xinying Wang et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Neonatal wearable device for colorimetry-based real-time detection of jaundice with simultaneous sensing of vitals
- (2021) Go Inamori et al. Science Advances
- UGT1A1 dysfunction increases liver burden and aggravates hepatocyte damage caused by long-term bilirubin metabolism disorder
- (2021) Dan Liu et al. BIOCHEMICAL PHARMACOLOGY
- Design, Synthesis, and Structure–Activity Relationship of N-Aryl-N′-(thiophen-2-yl)thiourea Derivatives as Novel and Specific Human TLR1/2 Agonists for Potential Cancer Immunotherapy
- (2021) Zhipeng Chen et al. JOURNAL OF MEDICINAL CHEMISTRY
- Oridonin interferes with simple steatosis of liver cells by regulating autophagy
- (2021) Boning Cheng et al. TISSUE & CELL
- Differential role of LXRα and LXRβ in the regulation of UDP-glucuronosyltransferase 1A1 in humanized UGT1 mice
- (2020) Eva Hansmann et al. DRUG METABOLISM AND DISPOSITION
- Oridonin alleviates d‐ Gal N/LPS ‐induced acute liver injury by inhibiting NLRP3 inflammasome
- (2020) Tao Zhang et al. DRUG DEVELOPMENT RESEARCH
- Regulation of cytochrome P450 4F11 expression by liver X receptor alpha
- (2020) Tao Zhang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Biological mechanisms and related natural modulators of liver X receptor in nonalcoholic fatty liver disease
- (2019) Mingzhu Ni et al. BIOMEDICINE & PHARMACOTHERAPY
- The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma
- (2019) Jacopo Baglieri et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Oridonin synergistically enhances the anti-tumor efficacy of doxorubicin against aggressive breast cancer via pro-apoptotic and anti-angiogenic effects
- (2019) Jingjing Li et al. PHARMACOLOGICAL RESEARCH
- Gender differences in the hepatotoxicity and toxicokinetics of emodin: The potential mechanisms mediated by UGT2B7 and MRP2
- (2018) Lili Wu et al. MOLECULAR PHARMACEUTICS
- Functional Characterization of a Novel Lipopolysaccharide-Binding Antimicrobial and Anti-Inflammatory Peptide in Vitro and in Vivo
- (2018) Baishuang Zeng et al. JOURNAL OF MEDICINAL CHEMISTRY
- Simultaneous characterization and quantification of 17 main compounds in Rabdosia rubescens by high performance liquid chromatography
- (2017) Sen Guo et al. JOURNAL OF FOOD AND DRUG ANALYSIS
- Recent Development of Oridonin Derivatives with Diverse Pharmacological Activities
- (2017) Weiyan Cheng et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Ethnopharmacological Approaches for Therapy of Jaundice: Part I
- (2017) Devesh Tewari et al. Frontiers in Pharmacology
- Relation of Transcriptional Factors to the Expression and Activity of Cytochrome P450 and UDP-Glucuronosyltransferases 1A in Human Liver: Co-Expression Network Analysis
- (2016) Shilong Zhong et al. AAPS Journal
- Combined oridonin with cetuximab treatment shows synergistic anticancer effects on laryngeal squamous cell carcinoma: Involvement of inhibition of EGFR and activation of reactive oxygen species-mediated JNK pathway
- (2016) Shijie Cao et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- UGT genotyping in belinostat dosing
- (2016) Andrew K.L. Goey et al. PHARMACOLOGICAL RESEARCH
- Time-Dependent Metabolism of Luteolin by Human UDP-Glucuronosyltransferases and Its Intestinal First-Pass Glucuronidation in Mice
- (2015) Lili Wu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients
- (2015) Linlin Lu et al. PLoS One
- Gene Replacement Therapy for Genetic Hepatocellular Jaundice
- (2014) Remco van Dijk et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Oridonin inhibits hepatic stellate cell proliferation and fibrogenesis
- (2014) Fredrick J. Bohanon et al. JOURNAL OF SURGICAL RESEARCH
- Liver X receptors: Emerging therapeutic targets for Alzheimer's disease
- (2013) Rupinder K. Sodhi et al. PHARMACOLOGICAL RESEARCH
- The Evolving Landscape of Neurotoxicity by Unconjugated Bilirubin: Role of Glial Cells and Inflammation
- (2012) Dora Brites Frontiers in Pharmacology
- Autophagy enhanced phagocytosis of apoptotic cells by oridonin-treated human histocytic lymphoma U937 cells
- (2011) Linghe Zang et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression
- (2011) Rakesh Kundu et al. BIOCHEMICAL PHARMACOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started