Article
Oncology
Xiang Liu, Ge Jin, Qiang Tang, Shumin Huang, Yujie Zhang, Yue Sun, Tianyu Liu, Zixuan Guo, Cheng Yang, Bangmao Wang, Kui Jiang, Weilong Zhong, Hailong Cao
Summary: Early life colonisation with Lactobacillus rhamnosus GG (LGG) can inhibit intestinal tumour formation in offspring by influencing gut microbiota composition and regulating signaling pathways.
BRITISH JOURNAL OF CANCER
(2022)
Article
Multidisciplinary Sciences
Dae Hee Han, Woon-ki Kim, Cheonghoon Lee, SungJun Park, Kiuk Lee, Sung Jae Jang, GwangPyo Ko
Summary: This study investigated the effects of co-administration of L. gasseri KBL697 and IFX on colitis in mice. The results showed that the combined treatment improved inflammation symptoms, modulated inflammatory cytokine production, and affected gut microbiota and metabolic pathways.
SCIENTIFIC REPORTS
(2022)
Editorial Material
Multidisciplinary Sciences
Mark A. Travis, Chiara Romagnani
Summary: Active control of the immune system is necessary to prevent inflammatory bowel disease. Cell populations that promote the generation of immunosuppressive regulatory T cells in the gut have been identified.
Article
Medicine, Research & Experimental
Zhibo Zeng, Zonghao Huang, Wen Yue, Shah Nawaz, Xinzhu Chen, Jing Liu
Summary: The administration of Lactobacillus plantarum has significant immunoenhancing effects in immunosuppressed mice, restoring specific immune markers in the spleen and increasing the number of goblet cells in the intestine. Microbial taxonomic analysis showed changes in the gut microbiota composition, with a decrease in Firmicutes and an increase in Verrucomicrobia and Actinobacteria. Additionally, treatment with Lactobacillus plantarum restored mRNA expression of inflammatory cytokines.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Gastroenterology & Hepatology
Hsin-Chih Lai, Tzu-Lung Lin, Ting-Wen Chen, Yu-Lun Kuo, Chih-Jung Chang, Tsung-Ru Wu, Ching-Chung Shu, Ying-Huang Tsai, Simon Swift, Chia-Chen Lu
Summary: The study found that gut microbiota composition significantly affects cigarette smoking-induced COPD development, and fecal microbiota transplantation can restore COPD pathogenesis. A beneficial bacterium Parabacteroides goldsteinii was isolated and shown to ameliorate COPD, with its derived active component having anti-inflammatory effects and ameliorating COPD through inhibition of lung inflammation and regulation of host metabolism.
Article
Biochemistry & Molecular Biology
Bernadette B. Bagon, Ju Kyoung Oh, Valerie Diane V. Valeriano, Edward Alain B. Pajarillo, Dae-Kyung Kang
Summary: Lactobacillus sp. have great potential in probiotic applications, and specific proteins in their exoproteome may have beneficial effects on the host gut.
Editorial Material
Multidisciplinary Sciences
Alice Bertocchi, Fiona Powrie
Summary: Abnormalities in gut bacteria can lead to hard-to-treat illnesses like inflammatory bowel diseases. Targeting bacteria with viruses shows promise in addressing these conditions.
Article
Biotechnology & Applied Microbiology
S. E. Assad, I. S. Rolny, J. Minnaard, P. F. Perez
Summary: This study investigated the interaction of bifidobacteria with phagocytic cells, revealing different patterns of interaction and cell responses among strains. The findings highlight the importance of understanding the mechanisms involved in the beneficial effects of probiotics by studying their interaction with key players of the host immune response.
JOURNAL OF APPLIED MICROBIOLOGY
(2021)
Editorial Material
Multidisciplinary Sciences
Stuart M. Brierley
Summary: Gut infection can trigger localized immune responses that cause harmless foods to be perceived as harmful, leading to persistent pain. Defense against bacterial infection may drive pain when eating food.
Article
Food Science & Technology
Jiayan Jiang, Ke Li, Yuanliang Wang, Zhongqin Wu, Huiqin Ma, Shilin Zheng, Zongjun Li
Summary: This study isolated and identified 104 strains of LAB from traditionally fermented vegetables, fresh milk, healthy infant feces, and other environments. The strains were evaluated for their antibacterial properties, acid and bile salts resistance, digestive enzymes resistance, and adhesion ability. Three LAB strains with good comprehensive performance were obtained, which exhibited broad-spectrum antibacterial properties, good acid resistance, and adhesion ability. These strains met the required characteristics and safety evaluation criteria for potential probiotics.
Article
Food Science & Technology
Marcos Ubiratam Filgueira Oliveira Menezes, Gabriel Cicalese Bevilaqua, Italo Ricardo da Silva Nascimento, Graciliane Nobre da Cruz Ximenes, Samara Alvachian Cardoso Andrade, Neila Mello dos Santos Cortez Barbosa
Summary: Contamination by pathogenic bacteria is the main cause of foodborne diseases, but adding probiotics can help fight against these pathogens. This research evaluated the behavior of Lactobacillus acidophilus against pathogenic strains in goat milk yogurt using mathematical models. The results showed that adding probiotics can reduce the amount of Pseudomonas aeruginosa, but is less effective against Escherichia coli.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2023)
Article
Multidisciplinary Sciences
Blanda Di Luccia, Vittoria Acampora, Anella Saggese, Viola Calabro, Maria Vivo, Tiziana Angrisano, Loredana Baccigalupi, Ezio Ricca, Alessandra Pollice
Summary: The gut microbiota plays a positive role in maintaining intestinal homeostasis through various mechanisms. This study investigated the effects of molecules secreted by Lactobacillus gasseri SF1183 on HCT116 cells and found that these molecules can reversibly reduce cell proliferation and protect cells from apoptosis. Additionally, they enhance the barrier function between cells.
SCIENTIFIC REPORTS
(2022)
Article
Food Science & Technology
Liya Mei, Ying Chen, Jialiang Wang, Jian Lu, Jianxin Zhao, Hao Zhang, Gang Wang, Wei Chen
Summary: This study aimed to explore the effect of different strains of Lactobacillus fermentum on IgA secretion from intestinal mucosa, and found that different strains have different stimulating effects. Additionally, it was speculated that different strains may stimulate IgA production through non-inflammatory pathways.
Article
Gastroenterology & Hepatology
Joshua A. Owens, Bejan J. Saeedi, Crystal R. Naudin, Sarah Hunter-Chang, Maria E. Barbian, Richard U. Eboka, Lauren Askew, Trevor M. Darby, Brian S. Robinson, Rheinallt M. Jones
Summary: The study shows that oral administration of Lactobacillus rhamnosus GG can enhance colonic CD8 T-cell responses in mice and reduce tumor burden. This suggests the potential use of LGG to augment antitumor immune responses in colorectal cancer patients and increase the efficacy of immunotherapy.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Neurosciences
Yunpeng Liu, Danya Sanderson, M. Firoz Mian, Karen-Anne McVey Neufeld, Paul Forsythe
Summary: The study investigated the impact of subdiaphragmatic vagotomy on the anxiolytic effects of L.rhamnosus and found that the vagus nerve plays a crucial role in modulating immune changes associated with this effect. Vagotomy prevented the anxiolytic effects, immune cell increase, and altered microglia activation in the hippocampus, highlighting the importance of vagal signaling in the microbiota-gut-brain axis.
Article
Allergy
J. -L. Fauquert, E. Michaud, B. Pereira, L. Bernard, N. Gourdon-Dubois, P. -O. Rouzaire, E. Rochette, E. Merlin, B. Evrard
CLINICAL AND EXPERIMENTAL ALLERGY
(2018)
Article
Allergy
D. Caillaud, M. Cheriaux, S. Martin, C. Segala, N. Dupuy, B. Evrard, M. Thibaudon
CLINICAL AND EXPERIMENTAL ALLERGY
(2018)
Correction
Cell Biology
Emmanuelle Rochette, Pascale Duche, Christophe Hourde, Bertrand Evrard, Bruno Pereira, Stephane Echaubard, Etienne Merlin
MEDIATORS OF INFLAMMATION
(2018)
Letter
Respiratory System
Denis M. Caillaud, Sylvie Martin, Claire Segala, Bertrand Evrard, Nihade Adrouche
EUROPEAN RESPIRATORY JOURNAL
(2019)
Article
Immunology
Marjolaine Vareille-Delarbre, Sylvie Miquel, Sophie Garcin, Thomas Bertran, Damien Balestrin, Bertrand Evrard, Christiane Forestier
INFECTION AND IMMUNITY
(2019)
Article
Medical Laboratory Technology
Anne Sarrat, Remy Couderc, Marie-Alexandra Alyanakian, Pol-Andre Apoil, Celine Beauvillain, Lionel Chollet, Pascale Chretien, Arnaud Ciree, Benoit Cypriani, Erwan Dumontet, Bertrand Evrard, Lorna Garnier, Angelique Grenier, Valerie Guerin, Caroline Hemont, Anthony Leon, Delphine Mariotte, Pascale Nicaise-Roland, Martine Pernollet, Stephanie Rogeau, Thierry Tabary, Beatrice Uring-Lambert, Mylene Vivinus, Joana Vitte
ANNALES DE BIOLOGIE CLINIQUE
(2020)
Letter
Dermatology
J. Rouanet, E. Lang, F. Beltzung, B. Evrard, C. Henquell, I. Joulie, M. D'Incan
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2020)
Review
Biophysics
Melina Bailly, Bertrand Evrard, Emmanuel Coudeyre, Corinne Rochette, Laurent Meriade, Christelle Blavignac, Anne-Cecile Fournier, Yves-Jean Bignon, Frederic Dutheil, Martine Duclos, David Thivel
Summary: With the highly variable symptoms of COVID-19, there is a need for early and individualized rehabilitation strategies. Hydrothermal centers can provide alternative treatments for COVID-19 patients, integrating alternative medicine, respiratory care, physical activity, and psychological support in relaxing environments under medical supervision.
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
(2022)
Article
Medicine, General & Internal
Benjamin Bonnet, Justine Cosme, Claire Dupuis, Elisabeth Coupez, Mireille Adda, Laure Calvet, Laurie Fabre, Pierre Saint-Sardos, Marine Bereiziat, Magali Vidal, Henri Laurichesse, Bertrand Souweine, Bertrand Evrard
Summary: The study analyzed 134 patients and found that higher blood IL-6 levels, lower quantitative expression of HLA-DR on blood monocytes, and higher IL-6/mHLA-DR ratios were associated with increased risk of severe forms of COVID-19 and death. These results suggest that patients with severe COVID-19 have a unique immunological profile involving moderate cytokine inflammation and severe monocyte dysregulation.
Article
Pediatrics
Julie Magnier, Valerie Julian, Aurelien Mulliez, Alexandra Usclade, Emmanuelle Rochette, Bertrand Evrard, Flore Amat, Carole Egron
Summary: The study revealed that male infants with a family history of allergies may be at higher risk for asthma at school age following their first episode of acute bronchiolitis. Additionally, rhinovirus infection and specific gene may have significant associations with asthma at age seven.
Letter
Infectious Diseases
Benjamin Bonnet, Helene Chabrolles, Christine Archimbaud, Amelie Brebion, Maud Godignon, Frederic Dutheil, Celine Lambert, Justine Cosme, Audrey Mirand, Amandine Ollier, Bruno Pereira, Christel Regagnon, Magali Vidal, Bertrand Evrard, Cecile Henquell
JOURNAL OF INFECTION
(2022)
Letter
Allergy
Brice Pascal, Bertrand Evrard, Etienne Merlin, Carole Egron, Benjamin Bonnet, Elodie Michaud
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Article
Immunology
Benjamin Bonnet, Helene Chabrolles, Christine Archimbaud, Amelie Brebion, Justine Cosme, Frederic Dutheil, Celine Lambert, Maud Junda, Audrey Mirand, Amandine Ollier, Bruno Pereira, Christel Regagnon, Magali Vidal, Bertrand Evrard, Cecile Henquell
Summary: Clinical trials and real-world evidence have shown that COVID-19 vaccines are effective against severe disease and death, but the durability of protection is still unknown. A study on healthcare workers who received the BNT162b2 mRNA vaccine found that antibody levels decreased between 3 and 6 months after full vaccination, particularly in individuals over 60 years old. T-cell immune responses also declined over time, although some individuals showed an increase in T-cell response. Ongoing follow-up is needed to understand the long-term protection provided by these vaccines.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Alice Ruault, Carole Philipponnet, Vincent Sapin, Bertrand Evrard, Radhia Bouzgarrou, Laure Calvet, Francois Thouy, Kevin Grapin, Benjamin Bonnet, Mireille Adda, Bertrand Souweine, Claire Dupuis
Summary: This retrospective study examined the epidemiology and outcome of early-onset acute kidney injury (EO-AKI) and recovery in ICU patients admitted for SARS-CoV-2 pneumonia. The findings revealed a significant association between the occurrence and severity of EO-AKI and poor patient outcomes.
Article
Immunology
Nicolas Goncalves-Mendes, Jeremie Talvas, Christian Duale, Aline Guttmann, Violaine Corbin, Geoffroy Marceau, Vincent Sapin, Patrick Brachet, Bertrand Evrard, Henri Laurichesse, Marie-Paule Vasson
FRONTIERS IN IMMUNOLOGY
(2019)