Histone H3.3 phosphorylation promotes heterochromatin formation by inhibiting H3K9/K36 histone demethylase

Mutations inhibiting KDM4B drive ALT activation in ATRX-mutated glioblastomas

(2021) M. Udugama et al.   Nature Communications

Histone variant H3.3 residue S31 is essential for Xenopus gastrulation regardless of the deposition pathway

(2020) David Sitbon et al.   Nature Communications

Histone H3.3 phosphorylation amplifies stimulation-induced transcription

(2020) Anja Armache et al.   NATURE

Phosphorylation of histone H3.3 at serine 31 promotes p300 activity and enhancer acetylation

(2019) Sara Martire et al.   NATURE GENETICS

Differential Expression of Histone H3.3 Genes and Their Role in Modulating Temperature Stress Response inCaenorhabditis elegans

(2018) Kamila Delaney et al.   GENETICS

Differential Expression of Histone H3.3 Genes and Their Role in Modulating Temperature Stress Response inCaenorhabditis elegans

(2018) Kamila Delaney et al.   GENETICS

Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma

(2018) Hsiao P. J. Voon et al.   Nature Communications

PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX

(2017) Erwan Delbarre et al.   GENOME RESEARCH

Phase separation drives heterochromatin domain formation

(2017) Amy R. Strom et al.   NATURE

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

(2017) Adam G. Larson et al.   NATURE

Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity

(2017) Foong Lyn Chan et al.   NUCLEIC ACIDS RESEARCH

Histone H3.3 promotes IgV gene diversification by enhancing formation of AID‐accessible single‐stranded DNA

(2016) Marina Romanello et al.   EMBO JOURNAL

New players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperone

(2016) Hsiao P.J. Voon et al.   NUCLEIC ACIDS RESEARCH

Atrx promotes heterochromatin formation at retrotransposons

(2015) D. Sadic et al.   EMBO REPORTS

Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells

(2015) Simon J. Elsässer et al.   NATURE

CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells

(2015) Fiona T. M. Chang et al.   NUCLEIC ACIDS RESEARCH

ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes

(2015) Hsiao P.J. Voon et al.   Cell Reports

Contribution of the Two Genes Encoding Histone Variant H3.3 to Viability and Fertility in Mice

(2015) Michelle C. W. Tang et al.   PLoS Genetics

Sequencing the Mouse Y Chromosome Reveals Convergent Gene Acquisition and Amplification on Both Sex Chromosomes

(2014) Y.Q. Shirleen Soh et al.   CELL

Histone H3.3 Is Required to Maintain Replication Fork Progression after UV Damage

(2014) Alexander Frey et al.   CURRENT BIOLOGY

The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity

(2014) Kristina Ivanauskiene et al.   GENOME RESEARCH

ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression

(2014) Hong Wen et al.   NATURE

Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma

(2014) Adam M Fontebasso et al.   NATURE GENETICS

KDM4/JMJD2 Histone Demethylases: Epigenetic Regulators in Cancer Cells

(2013) W. L. Berry et al.   CANCER RESEARCH

Histone variants in pluripotency and disease

(2013) P. J. Skene et al.   DEVELOPMENT

H3.3 actively marks enhancers and primes gene transcription via opening higher-ordered chromatin

(2013) P. Chen et al.   GENES & DEVELOPMENT

Conditional allelic replacement applied to genes encoding the histone variant H3.3 in the mouse

(2013) Michelle C.W. Tang et al.   GENESIS

Distinct and Combinatorial Functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in Mouse Embryonic Stem Cell Identity

(2013) Partha Pratim Das et al.   MOLECULAR CELL

PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells

(2013) Fiona T. M. Chang et al.   NUCLEIC ACIDS RESEARCH

Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development

(2013) Kelly M Bush et al.   Epigenetics & Chromatin

Drosophila Yemanuclein and HIRA Cooperate for De Novo Assembly of H3.3-Containing Nucleosomes in the Male Pronucleus

(2013) Guillermo A. Orsi et al.   PLoS Genetics

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

(2012) Dominik Sturm et al.   CANCER CELL

DAXX-dependent supply of soluble (H3.3-H4) dimers to PML bodies pending deposition into chromatin

(2012) E. Delbarre et al.   GENOME RESEARCH

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

(2012) Jeremy Schwartzentruber et al.   NATURE

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

(2012) Gang Wu et al.   NATURE GENETICS

Dynamics of Histone H3 Deposition In Vivo Reveal a Nucleosome Gap-Filling Mechanism for H3.3 to Maintain Chromatin Integrity

(2011) Dominique Ray-Gallet et al.   MOLECULAR CELL

Altered Telomeres in Tumors with ATRX and DAXX Mutations

(2011) C. M. Heaphy et al.   SCIENCE

DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors

(2011) Y. Jiao et al.   SCIENCE

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

(2010) Aaron D. Goldberg et al.   CELL

ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner

(2010) Martin J. Law et al.   CELL

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

(2010) P. Drane et al.   GENES & DEVELOPMENT

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

(2010) L. H. Wong et al.   GENOME RESEARCH

Conserved Antagonism between JMJD2A/KDM4A and HP1γ during Cell Cycle Progression

(2010) Joshua C. Black et al.   MOLECULAR CELL

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

(2010) P. W. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estimating enrichment of repetitive elements from high-throughput sequence data

(2010) Daniel S Day et al.   GENOME BIOLOGY

Transcriptional and Developmental Functions of the H3.3 Histone Variant in Drosophila

(2009) Akiko Sakai et al.   CURRENT BIOLOGY

Transcription in the Absence of Histone H3.3

(2009) Martina Hödl et al.   CURRENT BIOLOGY

Histone H3.3 incorporation provides a unique and functionally essential telomeric chromatin in embryonic stem cells

(2009) L. H. Wong et al.   GENOME RESEARCH