The unique chemistry and biology of the piericidins

Elucidating Hydroxylation and Methylation Steps Tailoring Piericidin A1 Biosynthesis

(2014) Yaolong Chen et al.   ORGANIC LETTERS

Piericidin A Aggravates Tau Pathology in P301S Transgenic Mice

(2014) Matthias Höllerhage et al.   PLoS One

Synthesis and SAR of Lehualide B: A Marine-Derived Natural Product with Potent Anti-Multiple Myeloma Activity

(2013) Valer Jeso et al.   ACS Chemical Biology

An NF-κB-Based High-Throughput Screen Identifies Piericidins as Inhibitors of the Yersinia pseudotuberculosis Type III Secretion System

(2013) Miles C. Duncan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Isoniazid-induced cell death is precipitated by underlying mitochondrial complex I dysfunction in mouse hepatocytes

(2013) Kang Kwang Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Enantioselective Total Syntheses and Absolute Configuration of JBIR-02 and Mer-A2026B

(2013) Johannes Hoecker et al.   ORGANIC LETTERS

Elucidation of Piericidin A1 Biosynthetic Locus Revealed a Thioesterase-Dependent Mechanism of α-Pyridone Ring Formation

(2012) Qian Liu et al.   CHEMISTRY & BIOLOGY

Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson’s disease model

(2011) Won-Seok Choi et al.   JOURNAL OF CELL BIOLOGY

Metabolomic Identification of the Target of the Filopodia Protrusion Inhibitor Glucopiericidin A

(2010) Mitsuhiro Kitagawa et al.   CHEMISTRY & BIOLOGY

Glucopiericidin C: a cytotoxic piericidin glucoside antibiotic produced by a marine Streptomyces isolate

(2010) Khaled A Shaaban et al.   JOURNAL OF ANTIBIOTICS

Symbiotic streptomycetes provide antibiotic combination prophylaxis for wasp offspring

(2010) Johannes Kroiss et al.   Nature Chemical Biology

Total Synthesis of Piericidin A1. Application of a Modified Negishi Carboalumination-Nickel-Catalyzed Cross-Coupling

(2009) Bruce H. Lipshutz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total synthesis of (+)-piericidin A1 and (−)-piericidin B1

(2009) Ryosuke Kikuchi et al.   TETRAHEDRON-ASYMMETRY

Differential effects of mitochondrial Complex I inhibitors on production of reactive oxygen species

(2008) Romana Fato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Etoposide-resistant HT-29 human colon carcinoma cells during glucose deprivation are sensitive to piericidin A, a GRP78 down-regulator

(2007) Ji-Hwan Hwang et al.   JOURNAL OF CELLULAR PHYSIOLOGY