miR‐126 downregulates CXCL12 expression in intestinal epithelial cells to suppress the recruitment and function of macrophages and tumorigenesis in a murine model of colitis‐associated colorectal cancer
出版年份 2022 全文链接
标题
miR‐126 downregulates
CXCL12
expression in intestinal epithelial cells to suppress the recruitment and function of macrophages and tumorigenesis in a murine model of colitis‐associated colorectal cancer
作者
关键词
-
出版物
Molecular Oncology
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2022-04-02
DOI
10.1002/1878-0261.13218
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- MiR-26a attenuates colitis and colitis-associated cancer by targeting the multiple intestinal inflammatory pathways
- (2021) Wei Zhang et al. Molecular Therapy-Nucleic Acids
- Tspan5 promotes epithelial‐mesenchymal transition and tumour metastasis of hepatocellular carcinoma by activating Notch signalling
- (2021) Qian Xie et al. Molecular Oncology
- MicroRNA-146a limits tumorigenic inflammation in colorectal cancer
- (2021) Lucien P. Garo et al. Nature Communications
- TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer
- (2021) Abu Osman et al. NATURE IMMUNOLOGY
- Epigenetics of colorectal cancer: biomarker and therapeutic potential
- (2020) Gerhard Jung et al. Nature Reviews Gastroenterology & Hepatology
- Resolution of Inflammation and Gut Repair in IBD: Translational Steps Towards Complete Mucosal Healing
- (2020) Gwo-tzer Ho et al. INFLAMMATORY BOWEL DISEASES
- Cytokine Networks in the Pathophysiology of Inflammatory Bowel Disease
- (2019) Matthias Friedrich et al. IMMUNITY
- The Immunobiology of the Interleukin-12 Family: Room for Discovery
- (2019) Elia D. Tait Wojno et al. IMMUNITY
- Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis
- (2019) Chen Wei et al. Molecular Cancer
- Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis
- (2019) Christopher S. Smillie et al. CELL
- Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD
- (2019) Yi Rang Na et al. Nature Reviews Gastroenterology & Hepatology
- Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy
- (2019) Jerome C. Martin et al. CELL
- Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies
- (2019) NaNa Keum et al. Nature Reviews Gastroenterology & Hepatology
- Tumor-Infiltrating Immune Cells Act as a Marker for Prognosis in Colorectal Cancer
- (2019) Lele Ye et al. Frontiers in Immunology
- Targeting the IL-6/JAK/STAT3 signalling axis in cancer
- (2018) Daniel E. Johnson et al. Nature Reviews Clinical Oncology
- miRWalk: An online resource for prediction of microRNA binding sites
- (2018) Carsten Sticht et al. PLoS One
- MiR-126 negatively regulates PLK-4 to impact the development of hepatocellular carcinoma via ATR/CHEK1 pathway
- (2018) Jie Bao et al. Cell Death & Disease
- Repression of MicroRNA Function Mediates Inflammation-associated Colon Tumorigenesis
- (2017) Takeshi Yoshikawa et al. GASTROENTEROLOGY
- MicroRNA 301A Promotes Intestinal Inflammation and Colitis-Associated Cancer Development by Inhibiting BTG1
- (2017) Chong He et al. GASTROENTEROLOGY
- MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
- (2017) Rajesha Rupaimoole et al. NATURE REVIEWS DRUG DISCOVERY
- Clonal evolution of colorectal cancer in IBD
- (2017) Chang-Ho R. Choi et al. Nature Reviews Gastroenterology & Hepatology
- Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancer
- (2017) Eva Pastille et al. PLoS Pathogens
- MicroRNA profiles in colorectal carcinomas, adenomas and normal colonic mucosa: variations in miRNA expression and disease progression
- (2016) Martha L. Slattery et al. CARCINOGENESIS
- Mango polyphenolics reduce inflammation in intestinal colitis-involvement of the miR-126/PI3K/AKT/mTOR axis in vitro and in vivo
- (2016) Hyemee Kim et al. MOLECULAR CARCINOGENESIS
- MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway
- (2016) Wei Yuan et al. Oncotarget
- MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice
- (2015) Christos Polytarchou et al. GASTROENTEROLOGY
- Novel evidence for an oncogenic role of microRNA-21 in colitis-associated colorectal cancer
- (2015) Chenzhang Shi et al. GUT
- Cytokines, IBD, and Colitis-associated Cancer
- (2015) Ralph Francescone et al. INFLAMMATORY BOWEL DISEASES
- CXCL12/CXCR4: a symbiotic bridge linking cancer cells and their stromal neighbors in oncogenic communication networks
- (2015) F Guo et al. ONCOGENE
- Tissue-based map of the human proteome
- (2015) M. Uhlen et al. SCIENCE
- Predicting effective microRNA target sites in mammalian mRNAs
- (2015) Vikram Agarwal et al. eLife
- Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype
- (2015) Katia Beider et al. Oncotarget
- CXCL12 secreted from adipose tissue recruits macrophages and induces insulin resistance in mice
- (2014) Dayea Kim et al. DIABETOLOGIA
- Dynamic changes and functions of macrophages and M1/M2 subpopulations during ulcerative colitis-associated carcinogenesis in an AOM/DSS mouse model
- (2014) WEI WANG et al. Molecular Medicine Reports
- Pomegranate polyphenolics suppressed azoxymethane-induced colorectal aberrant crypt foci and inflammation: possible role of miR-126/VCAM-1 and miR-126/PI3K/AKT/mTOR
- (2013) N. Banerjee et al. CARCINOGENESIS
- Crosstalk between colon cancer cells and macrophages via inflammatory mediators and CD47 promotes tumour cell migration
- (2013) Yuan Zhang et al. EUROPEAN JOURNAL OF CANCER
- Dynamic changes of peritoneal macrophages and subpopulations during ulcerative colitis to metastasis of colorectal carcinoma in a mouse model
- (2013) Wei Wang et al. INFLAMMATION RESEARCH
- MicroRNA-126 functions as a tumor suppressor in colorectal cancer cells by targeting CXCR4 via the AKT and ERK1/2 signaling pathways
- (2013) YALING LIU et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- MiR-126 suppresses colon cancer cell proliferation and invasion via inhibiting RhoA/ROCK signaling pathway
- (2013) Nan Li et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Expression of miR-126 suppresses migration and invasion of colon cancer cells by targeting CXCR4
- (2013) Zeng Li et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis
- (2013) Yun Zhang et al. NATURE CELL BIOLOGY
- Dynamic activation of the key pathways: linking colitis to colorectal cancer in a mouse model
- (2012) Anliu Tang et al. CARCINOGENESIS
- Risk of Colorectal Cancer in Patients With Ulcerative Colitis: A Meta-analysis of Population-Based Cohort Studies
- (2012) Tine Jess et al. Clinical Gastroenterology and Hepatology
- Incidence and Mortality of Colorectal Adenocarcinoma in Persons With Inflammatory Bowel Disease From 1998 to 2010
- (2012) Lisa J. Herrinton et al. GASTROENTEROLOGY
- Interleukin-6 - A Key Regulator of Colorectal Cancer Development
- (2012) Maximilian J. Waldner et al. International Journal of Biological Sciences
- Stromal cell-derived factor-1/CXCR4 promotes IL-6 production in human synovial fibroblasts
- (2011) Hsien-Te Chen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- MiR-126 Acts as a Tumor Suppressor in Pancreatic Cancer Cells via the Regulation of ADAM9
- (2011) S. Hamada et al. MOLECULAR CANCER RESEARCH
- miR-126 functions as a tumour suppressor in human gastric cancer
- (2010) Runhua Feng et al. CANCER LETTERS
- Macrophage Diversity Enhances Tumor Progression and Metastasis
- (2010) Bin-Zhi Qian et al. CELL
- Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12
- (2010) Antonella Rigo et al. Molecular Cancer
- The widespread regulation of microRNA biogenesis, function and decay
- (2010) Jacek Krol et al. NATURE REVIEWS GENETICS
- Identification of Restricted Subsets of Mature microRNA Abnormally Expressed in Inactive Colonic Mucosa of Patients with Inflammatory Bowel Disease
- (2010) Magali Fasseu et al. PLoS One
- CXCR4 antagonist AMD3100 attenuates colonic damage in mice with experimental colitis
- (2010) Xian-Ming Xia WORLD JOURNAL OF GASTROENTEROLOGY
- Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways
- (2009) A. J. Schetter et al. CARCINOGENESIS
- Reactivation of Inflammatory Bowel Disease in a Mouse Model of Depression
- (2009) Jean–Eric Ghia et al. GASTROENTEROLOGY
- CXCL12 Is a constitutive and inflammatory chemokine in the intestinal immune system
- (2009) Iris Dotan et al. INFLAMMATORY BOWEL DISEASES
- Expression of SDF-1α and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer
- (2008) N Yoshitake et al. BRITISH JOURNAL OF CANCER
- Stromal cell-derived factor-1α (SDF-1α/CXCL12)-enhanced angiogenesis of human basal cell carcinoma cells involves ERK1/2–NF-κB/interleukin-6 pathway
- (2008) Chia-Yu Chu et al. CARCINOGENESIS
- MicroRNAs Are Differentially Expressed in Ulcerative Colitis and Alter Expression of Macrophage Inflammatory Peptide-2α
- (2008) Feng Wu et al. GASTROENTEROLOGY
- Intestinal fibrosis in inflammatory bowel disease — Current knowledge and future perspectives
- (2008) Florian Rieder et al. Journal of Crohns & Colitis
- Blockade of CXCL12/CXCR4 Axis Ameliorates Murine Experimental Colitis
- (2008) S. Mikami et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started