Coordination of two kinesin superfamily motor proteins, KIF3A and KIF13A, is essential for pericellular matrix degradation by membrane-type 1 matrix metalloproteinase (MT1-MMP) in cancer cells

Protrudin-mediated ER–endosome contact sites promote MT1-MMP exocytosis and cell invasion

(2020) Nina Marie Pedersen et al.   JOURNAL OF CELL BIOLOGY

MT1-MMP-dependent cell migration: proteolytic and non-proteolytic mechanisms

(2019) Valentina Gifford et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

MT1-MMP directs force-producing proteolytic contacts that drive tumor cell invasion

(2019) Robin Ferrari et al.   Nature Communications

Matrix modeling and remodeling: A biological interplay regulating tissue homeostasis and diseases

(2018) Nikos K. Karamanos et al.   MATRIX BIOLOGY

Rab22A recruits BLOC‐1 and BLOC‐2 to promote the biogenesis of recycling endosomes

(2018) Saurabh Shakya et al.   EMBO REPORTS

Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts

(2017) Iwona Majkowska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TrackMate: An open and extensible platform for single-particle tracking

(2017) Jean-Yves Tinevez et al.   METHODS

A pathology atlas of the human cancer transcriptome

(2017) Mathias Uhlen et al.   SCIENCE

Selective Inhibition of Membrane Type 1 Matrix Metalloproteinase Abrogates Progression of Experimental Inflammatory Arthritis: Synergy With Tumor Necrosis Factor Blockade

(2016) Kazuyo Kaneko et al.   Arthritis & Rheumatology

Hitting the brakes: targeting microtubule motors in cancer

(2015) Gayathri Chandrasekaran et al.   BRITISH JOURNAL OF CANCER

Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein

(2015) N. Koshikawa et al.   CANCER RESEARCH

Kinesin superfamily proteins (KIFs): Various functions and their relevance for important phenomena in life and diseases

(2015) Nobutaka Hirokawa et al.   EXPERIMENTAL CELL RESEARCH

ARF6–JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion

(2015) Valentina Marchesin et al.   JOURNAL OF CELL BIOLOGY

Membrane-type matrix metalloproteinases: Their functions and regulations

(2015) Yoshifumi Itoh   MATRIX BIOLOGY

The kinesin KIF16B mediates apical transcytosis of transferrin receptor in AP-1B-deficient epithelia

(2013) Andres E Perez Bay et al.   EMBO JOURNAL

MT-LOOP-dependent Localization of Membrane Type I Matrix Metalloproteinase (MT1-MMP) to the Cell Adhesion Complexes Promotes Cancer Cell Invasion

(2013) Anna M. Woskowicz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion

(2013) Nami Sugiyama et al.   JOURNAL OF CELL BIOLOGY

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis

(2012) Kui Ming Chan et al.   DEVELOPMENTAL CELL

Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK–p130Cas complex

(2012) Yu Wang et al.   JOURNAL OF CELL BIOLOGY

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Dimerization of MT1-MMP during cellular invasion detected by fluorescence resonance energy transfer

(2011) Yoshifumi Itoh et al.   BIOCHEMICAL JOURNAL

MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell development

(2011) Guoxiang Jin et al.   EMBO JOURNAL

KIF5B and KIF3A/KIF3B kinesins drive MT1-MMP surface exposure, CD44 shedding, and extracellular matrix degradation in primary macrophages

(2010) C. Wiesner et al.   BLOOD

Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen

(2010) Christian Roghi et al.   FEBS Journal

Membrane-Type I Matrix Metalloproteinase-Dependent Regulation of Rheumatoid Arthritis Synoviocyte Function

(2010) F. Sabeh et al.   JOURNAL OF IMMUNOLOGY

The kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomes

(2010) Susanne Cornfine et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis

(2009) Mary-Clare Miller et al.   ARTHRITIS AND RHEUMATISM

Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis

(2009) Laetitia Devy et al.   CANCER RESEARCH

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

(2009) Farideh Sabeh et al.   JOURNAL OF CELL BIOLOGY

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY