Dose selection of siltuximab for multicentric Castleman’s disease

Siltuximab for multicentric Castleman's disease: a randomised, double-blind, placebo-controlled trial

(2014) Frits van Rhee et al.   LANCET ONCOLOGY

Mechanistic Pharmacokinetic/Target Engagement/Pharmacodynamic (PK/TE/PD) Modeling in Deciphering Interplay Between a Monoclonal Antibody and Its Soluble Target in Cynomolgus Monkeys

(2013) Weirong Wang et al.   AAPS Journal

A Phase I, Open-Label Study of Siltuximab, an Anti-IL-6 Monoclonal Antibody, in Patients with B-cell Non-Hodgkin Lymphoma, Multiple Myeloma, or Castleman Disease

(2013) R. Kurzrock et al.   CLINICAL CANCER RESEARCH

Effects of atorvastatin on human C-reactive protein metabolism

(2012) Nuntakorn Thongtang et al.   ATHEROSCLEROSIS

Maximum-Tolerated Dose, Optimum Biologic Dose, or Optimum Clinical Value: Dosing Determination of Cancer Therapies

(2012) John L. Marshall   JOURNAL OF CLINICAL ONCOLOGY

A phase I/II study of siltuximab (CNTO 328), an anti-interleukin-6 monoclonal antibody, in metastatic renal cell cancer

(2010) J-F Rossi et al.   BRITISH JOURNAL OF CANCER

Pharmacokinetic and Pharmacodynamic Modeling of an Anti-Interleukin-6 Chimeric Monoclonal Antibody (Siltuximab) in Patients with Metastatic Renal Cell Carcinoma

(2010) T. Puchalski et al.   CLINICAL CANCER RESEARCH

Siltuximab, a Novel Anti–Interleukin-6 Monoclonal Antibody, for Castleman's Disease

(2010) Frits van Rhee et al.   JOURNAL OF CLINICAL ONCOLOGY

CRP identifies homeostatic immune oscillations in cancer patients: a potential treatment targeting tool?

(2009) Brendon J Coventry et al.   Journal of Translational Medicine

Iron Sequestration and Anemia of Inflammation

(2009) Tomas Ganz et al.   SEMINARS IN HEMATOLOGY

Autocrine IL-6 Signaling: A Key Event in Tumorigenesis?

(2008) Sergei Grivennikov et al.   CANCER CELL

Intravascular Kinetics of C-Reactive Protein and Their Relationships with Features of the Metabolic Syndrome

(2008) Jean-François Mauger et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM