Downregulated lincRNA HOTAIR expression in ovarian cancer stem cells decreases its tumorgeniesis and metastasis by inhibiting epithelial-mesenchymal transition

Overexpression of long non-coding RNA HOTAIR predicts poor patient prognosis and promotes tumor metastasis in epithelial ovarian cancer

(2014) Jun-jun Qiu et al.   GYNECOLOGIC ONCOLOGY

MiR-7, Inhibited Indirectly by LincRNA HOTAIR, Directly Inhibits SETDB1 and Reverses the EMT of Breast Cancer Stem Cells by Downregulating the STAT3 Pathway

(2014) Hongyi Zhang et al.   STEM CELLS

Gene therapy of ovarian cancer using IL-21-secreting human umbilical cord mesenchymal stem cells in nude mice

(2014) Yunxia Zhang et al.   Journal of Ovarian Research

Evaluation of characteristics of CD44+CD117+ ovarian cancer stem cells in three dimensional basement membrane extract scaffold versus two dimensional monocultures

(2013) Junsong Chen et al.   BMC CELL BIOLOGY

Effect of downregulation of ZEB1 on vimentin expression, tumour migration and tumourigenicity of melanoma B16F10 cells and CSCs

(2013) Jun Dou et al.   CELL BIOLOGY INTERNATIONAL

Enrichment of ovarian cancer stem-like cells is associated with epithelial to mesenchymal transition through an miRNA-activated AKT pathway

(2013) X. Luo et al.   CELL PROLIFERATION

Large Intervening Non-Coding RNA HOTAIR is Associated with Hepatocellular Carcinoma Progression

(2013) YJ Geng et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Anti-ABCG2 monoclonal antibody in combination with paclitaxel nanoparticles against cancer stem-like cell activity in multiple myeloma

(2013) Cuiping Yang et al.   Nanomedicine

VAV1 represses E-cadherin expression through the transactivation of Snail and Slug: a potential mechanism for aberrant epithelial to mesenchymal transition in human epithelial ovarian cancer

(2013) Senn Wakahashi et al.   Translational Research

MicroRNA-200c overexpression inhibits tumorigenicity and metastasis of CD117+CD44+ ovarian cancer stem cells by regulating epithelial-mesenchymal transition

(2013) Dengyu Chen et al.   Journal of Ovarian Research

PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice

(2012) B Shen et al.   BRITISH JOURNAL OF CANCER

Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors

(2012) T. Niinuma et al.   CANCER RESEARCH

In Vivo Delivery Aspects of miRNA, shRNA and siRNA

(2012) N. I. Khatri et al.   CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS

Antitumor efficacy of viable tumor vaccine modified by heterogenetic ESAT-6 antigen and cytokine IL-21 in melanomatous mouse

(2012) Xiangfeng He et al.   IMMUNOLOGIC RESEARCH

HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer

(2012) K Kim et al.   ONCOGENE

Phenotypic Characterization of Prostate Cancer LNCaP Cells Cultured within a Bioengineered Microenvironment

(2012) Shirly Sieh et al.   PLoS One

Molecular portraits of intratumoral heterogeneity in human ovarian cancer

(2011) Yoon Pyo Choi et al.   CANCER LETTERS

Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

(2011) R. Kogo et al.   CANCER RESEARCH

Using ABCG2-molecule-expressing side population cells to identify cancer stem-like cells in a human ovarian cell line

(2011) Jun Dou et al.   CELL BIOLOGY INTERNATIONAL

Ovarian cancer cells with the CD117 phenotype are highly tumorigenic and are related to chemotherapy outcome

(2011) Lijing Luo et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Augmenting Therapy of Ovarian Cancer Efficacy by Secreting IL-21 Human Umbilical Cord Blood Stem Cells in Nude Mice

(2010) Weihua Hu et al.   CELL TRANSPLANTATION

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

An ocular mucosal administration of nanoparticles containing DNA vaccine pRSC-gD-IL-21 confers protection against mucosal challenge with herpes simplex virus type 1 in mice

(2010) Kai Hu et al.   VACCINE

Potential for therapeutic targeting of tumor stem cells

(2009) Vaibhav Saini et al.   CANCER SCIENCE

Long noncoding RNAs: functional surprises from the RNA world

(2009) J. E. Wilusz et al.   GENES & DEVELOPMENT

Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: Evidence supporting a mesothelial-to-epithelial transition

(2009) Ausra Bendoraite et al.   GYNECOLOGIC ONCOLOGY

Identification and Characterization of Ovarian Cancer-Initiating Cells from Primary Human Tumors

(2008) S. Zhang et al.   CANCER RESEARCH