Increase of α-Secretase ADAM10 in Platelets Along Cognitively Healthy Aging

ADAM10 gene expression in the blood cells of Alzheimer's disease patients and mild cognitive impairment subjects

(2015) Patricia Regina Manzine et al.   BIOMARKERS

Galangin-induced down-regulation of BACE1 by epigenetic mechanisms in SH-SY5Y cells

(2015) H. Zeng et al.   NEUROSCIENCE

Tracking Early Decline in Cognitive Function in Older Individuals at Risk for Alzheimer Disease Dementia

(2015) Rebecca E. Amariglio et al.   JAMA Neurology

APOE ε4: The most prevalent yet understudied risk factor for Alzheimer's disease

(2014) Daniel M. Michaelson   Alzheimers & Dementia

Sex differences in Alzheimer's disease risk: are we looking at the wrong hormones?

(2014) Cynthia A. Munro   INTERNATIONAL PSYCHOGERIATRICS

Association of Structural Global Brain Network Properties with Intelligence in Normal Aging

(2014) Florian U. Fischer et al.   PLoS One

Life Extension Factor Klotho Enhances Cognition

(2014) Dena B. Dubal et al.   Cell Reports

Platelets, a reliable source for peripheral Alzheimer’s disease biomarkers?

(2014) Michael Veitinger et al.   Acta Neuropathologica Communications

ADAM10 as a Biomarker for Alzheimer’s Disease: A Study with Brazilian Elderly

(2013) Patricia Regina Manzine et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Unfolded protein response signaling by transcription factor XBP-1 regulates ADAM10 and is affected in Alzheimer's disease

(2013) Sven Reinhardt et al.   FASEB JOURNAL

Platelet a disintegrin and metallopeptidase 10 expression correlates with clock drawing test scores in Alzheimer's disease

(2013) Patrícia Regina Manzine et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

ADAM10 Missense Mutations Potentiate β-Amyloid Accumulation by Impairing Prodomain Chaperone Function

(2013) Jaehong Suh et al.   NEURON

Conformational altered p53 affects neuronal function: relevance for the response to toxic insult and growth-associated protein 43 expression

(2013) L Buizza et al.   Cell Death & Disease

Stage-Dependent Agreement between Cerebrospinal Fluid Proteins and FDG-PET Findings in Alzheimer's Disease

(2012) Igor Yakushev et al.   Current Alzheimer Research

Current application of neurochemical biomarkers in the prediction and differential diagnosis of Alzheimer’s disease and other neurodegenerative dementias

(2012) J. Genius et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Gender, sex steroid hormones, and Alzheimer's disease

(2012) Rebekah S. Vest et al.   HORMONES AND BEHAVIOR

Structural integrity of the corpus callosum predicts long-term transfer of fluid intelligence-related training gains in normal aging

(2012) Dominik Wolf et al.   HUMAN BRAIN MAPPING

Can platelet BACE1 levels be used as a biomarker for Alzheimer's disease? Proof-of-concept study

(2012) Boris Decourt et al.   PLATELETS

Regulation of alpha-secretase ADAM10 expression and activity

(2011) Kristina Endres et al.   EXPERIMENTAL BRAIN RESEARCH

Worldwide allele frequencies of the human apolipoprotein E gene: Climate, local adaptations, and evolutionary history

(2010) Dan T.A. Eisenberg et al.   AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY

ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons

(2010) Peer-Hendrik Kuhn et al.   EMBO JOURNAL

The “A Disintegrin And Metalloproteases” ADAM10 and ADAM17: Novel drug targets with therapeutic potential?

(2010) Paul Saftig et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The Disintegrin/Metalloproteinase ADAM10 Is Essential for the Establishment of the Brain Cortex

(2010) E. Jorissen et al.   JOURNAL OF NEUROSCIENCE

De novo protein synthesis in mature platelets: a consideration for transfusion medicine

(2010) P. Schubert et al.   VOX SANGUINIS

Up-regulation of the α-secretase ADAM10 by retinoic acid receptors and acitretin

(2009) Frank Tippmann et al.   FASEB JOURNAL

Klotho is a substrate for α-, β- and γ-secretase

(2009) Laura Bloch et al.   FEBS LETTERS

Protective actions of sex steroid hormones in Alzheimer’s disease

(2009) Christian J. Pike et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate α-secretase activity

(2009) Minji Kim et al.   HUMAN MOLECULAR GENETICS

Association ofFOXO3Avariation with human longevity confirmed in German centenarians

(2009) Friederike Flachsbart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA