Formation of stable imine intermediates in the coexistence of sulfamethoxazole and humic acid by electrochemical oxidation

The electrochemical degradation performance of sulfamethoxazole (SMX) was studied in the presence of humic acid (HA) by using a Ti/Ti4O7/beta-PbO2 anode. The electrochemical degradation efficiency of SMX decreased from 93.4% to 45.8% in 50 min after the addition of 25 mg L-1 HA. The pseudo-first-order kinetic rate constant decreased by 71.4%, and the EEO value increased from 63.8 Wh L-1 to 90.9 Wh L-1. HA and its degradation intermediates could compete for free radicals, especially for .OH, with SMX. The analytical results obtained using UPLC-ESI-Q-TOF-MS showed that 18 degradation intermediates were identified in the coexistence of SMX and HA. Four imine intermediates were formed through the reactions between the aniline moieties of SMX and quinone groups in the HA structure through covalent bonds. Furthermore, the relative abundances of the intermediates demonstrated that the imine intermediates were complex and stable during electrochemical degradation.

Automated summary

The electrochemical degradation performance of sulfamethoxazole (SMX) in the presence of humic acid (HA) was studied. The results showed that the presence of HA decreased the degradation efficiency of SMX and led to the formation of several degradation intermediates.