Positively charged amino acids at the N terminus of select mitochondrial proteins mediate early recognition by import proteins αβ′-NAC and Sam37

ER targeting of non-imported mitochondrial carrier proteins is dependent on the GET pathway

(2021) Tianyao Xiao et al.   Life Science Alliance

The ER protein Ema19 facilitates the degradation of non-imported mitochondrial precursor proteins

(2021) Janina Laborenz et al.   MOLECULAR BIOLOGY OF THE CELL

A nuclear-based quality control pathway for non-imported mitochondrial proteins

(2021) Viplendra PS Shakya et al.   eLife

From cytosol to mitochondria: the beginning of a protein journey

(2020) Maria Clara Avendaño-Monsalve et al.   BIOLOGICAL CHEMISTRY

Cytosolic Events in the Biogenesis of Mitochondrial Proteins

(2020) Yury S. Bykov et al.   TRENDS IN BIOCHEMICAL SCIENCES

A ribosome-associated chaperone enables substrate triage in a cotranslational protein targeting complex

(2020) Hao-Hsuan Hsieh et al.   Nature Communications

Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme

(2019) Felix Boos et al.   NATURE CELL BIOLOGY

Early Scanning of Nascent Polypeptides inside the Ribosomal Tunnel by NAC

(2019) Martin Gamerdinger et al.   MOLECULAR CELL

In vitro import experiments with semi-intact cells suggest a role of the Sec61 paralog Ssh1 in mitochondrial biogenesis

(2019) Janina Laborenz et al.   BIOLOGICAL CHEMISTRY

Compromised Mitochondrial Protein Import Acts as a Signal for UPRmt

(2019) Stéphane G. Rolland et al.   Cell Reports

MitoCPR—A surveillance pathway that protects mitochondria in response to protein import stress

(2018) Hilla Weidberg et al.   SCIENCE

An ER surface retrieval pathway safeguards the import of mitochondrial membrane proteins in yeast

(2018) Katja G. Hansen et al.   SCIENCE

αβ′-NAC cooperates with Sam37 to mediate early stages of mitochondrial protein import

(2017) José Carlos Ponce-Rojas et al.   FEBS Journal

Archaea and the origin of eukaryotes

(2017) Laura Eme et al.   NATURE REVIEWS MICROBIOLOGY

Landscape of submitochondrial protein distribution

(2017) F.-Nora Vögtle et al.   Nature Communications

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale

(2017) Marcel Morgenstern et al.   Cell Reports

An Essential Role for COPI in mRNA Localization to Mitochondria and Mitochondrial Function

(2016) Dmitry Zabezhinsky et al.   Cell Reports

Sam37 is crucial for formation of the mitochondrial TOM–SAM supercomplex, thereby promoting β-barrel biogenesis

(2015) Lena-Sophie Wenz et al.   JOURNAL OF CELL BIOLOGY

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol

(2015) Lidia Wrobel et al.   NATURE

The principle of antagonism ensures protein targeting specificity at the endoplasmic reticulum

(2015) M. Gamerdinger et al.   SCIENCE

Functional Dissection of the Nascent Polypeptide-Associated Complex in Saccharomyces cerevisiae

(2015) Ann-Kathrin Ott et al.   PLoS One

Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling

(2014) C. C. Williams et al.   SCIENCE

OM14 is a mitochondrial receptor for cytosolic ribosomes that supports co-translational import into mitochondria

(2014) Chen Lesnik et al.   Nature Communications

Coupling of Mitochondrial Import and Export Translocases by Receptor-Mediated Supercomplex Formation

(2013) Jian Qiu et al.   CELL

NAC functions as a modulator of SRP during the early steps of protein targeting to the endoplasmic reticulum

(2012) Ying Zhang et al.   MOLECULAR BIOLOGY OF THE CELL

Localization of mRNAs coding for mitochondrial proteins in the yeast Saccharomyces cerevisiae

(2011) N. Gadir et al.   RNA

Dual Binding Mode of the Nascent Polypeptide-associated Complex Reveals a Novel Universal Adapter Site on the Ribosome

(2010) Markus Pech et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability

(2009) F.-Nora Vögtle et al.   CELL

Importing Mitochondrial Proteins: Machineries and Mechanisms

(2009) Agnieszka Chacinska et al.   CELL

HELIQUEST: a web server to screen sequences with specific  -helical properties

(2008) R. Gautier et al.   BIOINFORMATICS