Antigenic analysis of the HIV-1 envelope trimer implies small differences between structural states 1 and 2

Cryo-EM Structure of Full-length HIV-1 Env Bound With the Fab of Antibody PG16

(2020) Junhua Pan et al.   JOURNAL OF MOLECULAR BIOLOGY

Long-Acting BMS-378806 Analogues Stabilize the State-1 Conformation of the Human Immunodeficiency Virus (HIV-1) Envelope Glycoproteins

(2020) Shitao Zou et al.   JOURNAL OF VIROLOGY

Fostemsavir in Adults with Multidrug-Resistant HIV-1 Infection

(2020) Michael Kozal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural basis of broad HIV neutralization by a vaccine-induced cow antibody

(2020) Robyn L. Stanfield et al.   Science Advances

Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles

(2020) Ze Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET

(2019) Maolin Lu et al.   NATURE

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

(2019) Alba Torrents de la Peña et al.   PLoS Pathogens

The lipid membrane of HIV-1 stabilizes the viral envelope glycoproteins and modulates their sensitivity to antibody neutralization

(2019) Hamid Salimi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Neutralizing Antibody Recognizing Primarily N -Linked Glycan Targets the Silent Face of the HIV Envelope

(2018) Tongqing Zhou et al.   IMMUNITY

HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations

(2018) Xiaochu Ma et al.   eLife

DEER Spectroscopy Measurements Reveal Multiple Conformations of HIV-1 SOSIP Envelopes that Show Similarities with Envelopes on Native Virions

(2018) Beth M. Stadtmueller et al.   IMMUNITY

Development of broadly neutralizing antibodies in HIV-1 infected elite neutralizers

(2018) Elise Landais et al.   Retrovirology

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

(2018) Yen-Ting Lai et al.   Nature Communications

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop

(2017) Evan M. Cale et al.   IMMUNITY

Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows

(2017) Devin Sok et al.   NATURE

Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike

(2017) Gabriel Ozorowski et al.   NATURE

Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529

(2017) Marie Pancera et al.   Nature Chemical Biology

The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions

(2017) Alon Herschhorn et al.   Nature Communications

Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design

(2016) Dennis R. Burton et al.   Annual Review of Immunology

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

(2016) Guillaume B.E. Stewart-Jones et al.   CELL

Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer

(2016) J. H. Lee et al.   SCIENCE

Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins

(2016) Alon Herschhorn et al.   mBio

Structural and genetic diversity in antibody repertoires from diverse species

(2015) Miguel de los Rios et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

(2015) Nicole A. Doria-Rose et al.   JOURNAL OF VIROLOGY

Viral membrane fusion

(2015) Stephen C. Harrison   VIROLOGY

Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers

(2014) Emilia Falkowska et al.   IMMUNITY

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface

(2014) Jinghe Huang et al.   NATURE

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

(2014) Nicole A. Doria-Rose et al.   NATURE

Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits

(2014) Anila Yasmeen et al.   Retrovirology

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

(2014) J. B. Munro et al.   SCIENCE

Broadly Neutralizing Antiviral Antibodies

(2013) Davide Corti et al.   Annual Review of Immunology

HIV-1 neutralizing antibodies: understanding nature's pathways

(2013) John R. Mascola et al.   IMMUNOLOGICAL REVIEWS

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

(2013) J.-P. Julien et al.   SCIENCE

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

(2013) D. Lyumkis et al.   SCIENCE

Antibodies in HIV-1 Vaccine Development and Therapy

(2013) F. Klein et al.   SCIENCE

HIV Entry and Envelope Glycoprotein-mediated Fusion

(2012) Robert Blumenthal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

(2012) H. Mouquet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broad neutralization coverage of HIV by multiple highly potent antibodies

(2011) Laura M. Walker et al.   NATURE

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

(2010) X. Wu et al.   SCIENCE

Tiered Categorization of a Diverse Panel of HIV-1 Env Pseudoviruses for Assessment of Neutralizing Antibodies

(2009) M. S. Seaman et al.   JOURNAL OF VIROLOGY

Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

(2009) M. Pancera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular architecture of native HIV-1 gp120 trimers

(2008) Jun Liu et al.   NATURE

Viral membrane fusion

(2008) Stephen C Harrison   NATURE STRUCTURAL & MOLECULAR BIOLOGY