Mitochondrial glutathione peroxidase 4 is indispensable for photoreceptor development and survival in mice

STING1 Promotes Ferroptosis Through MFN1/2-Dependent Mitochondrial Fusion

(2021) Changfeng Li et al.   Frontiers in Cell and Developmental Biology

Inhibition of lipid peroxidation during the reproductive period extends the lifespan of Caenorhabditis elegans

(2020) Taro Sakamoto et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Relative lipid oxidation associates directly with mitochondrial fusion phenotype and mitochondria-sarcoplasmic reticulum interactions in human skeletal muscle

(2020) Mauricio Castro-Sepulveda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Nrf2 inhibits ferroptosis and protects against acute lung injury due to intestinal ischemia reperfusion via regulating SLC7A11 and HO-1

(2020) Hui Dong et al.   Aging-US

Symmetric arrangement of mitochondria:plasma membrane contacts between adjacent photoreceptor cells regulated by Opa1

(2020) Ingrid P. Meschede et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis mediated by the interaction between Mfn2 and IREα promotes arsenic-induced nonalcoholic steatohepatitis

(2020) Sen Wei et al.   ENVIRONMENTAL RESEARCH

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis

(2019) Masahiro Yoshida et al.   Nature Communications

Involvement of GPx4-Regulated Lipid Peroxidation in Idiopathic Pulmonary Fibrosis Pathogenesis

(2019) Kazuya Tsubouchi et al.   JOURNAL OF IMMUNOLOGY

Mitochondria regulation in ferroptosis

(2019) Hai Wang et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Regulation of lipid peroxidation and ferroptosis in diverse species

(2018) Marcus Conrad et al.   GENES & DEVELOPMENT

The role of nonbilayer phospholipids in mitochondrial structure and function

(2017) Writoban Basu Ball et al.   FEBS LETTERS

Docosahexaenoic acid preserves visual function by maintaining correct disc morphology in retinal photoreceptor cells

(2017) Hideo Shindou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Erastin-Like Anti-Warburg Agents Prevent Mitochondrial Depolarization Induced by Free Tubulin and Decrease Lactate Formation in Cancer Cells

(2017) David N. DeHart et al.   SLAS Discovery

Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration

(2016) Bradley A. Carlson et al.   Redox Biology

Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis

(2015) Liuji Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics

(2012) Y Kanda   BONE MARROW TRANSPLANTATION

Vitamin E Protects against Lipid Peroxidation and Rescues Tumorigenic Phenotypes in Cowden/Cowden-like Patient-Derived Lymphoblast Cells with Germline SDHx Variants

(2012) Y. Ni et al.   CLINICAL CANCER RESEARCH

Docosahexaenoic Acid Signalolipidomics in Nutrition: Significance in Aging, Neuroinflammation, Macular Degeneration, Alzheimer's, and Other Neurodegenerative Diseases

(2011) Nicolas G. Bazan et al.   Annual Review of Nutrition

Glutathione Peroxidase 4 Is Required for Maturation of Photoreceptor Cells

(2011) Takashi Ueta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased vitamin E intake is associated with higher α-tocopherol concentration in the maternal circulation but higher α-carboxyethyl hydroxychroman concentration in the fetal circulation

(2010) Svetlana Didenco et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Short Form Glutathione Peroxidase 4 Is the Essential Isoform Required for Survival and Somatic Mitochondrial Functions

(2009) Hanyu Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Depletion of Selenoprotein GPx4 in Spermatocytes Causes Male Infertility in Mice

(2009) Hirotaka Imai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Expression of Glutathione Peroxidase 4 Strongly Protects Retina from Oxidative Damage

(2008) Lili Lu et al.   ANTIOXIDANTS & REDOX SIGNALING

Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells

(2008) Wan Seok Yang et al.   CHEMISTRY & BIOLOGY