PD-1 Targeted Nanoparticles Inhibit Activated T Cells and Alleviate Autoimmunity via Suppression of Cellular Energy Metabolism Mediated by PKM2

Deficiency of IL-27 Signaling Exacerbates Experimental Autoimmune Uveitis with Elevated Uveitogenic Th1 and Th17 Responses

(2021) Sihan Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intracellular delivery of anti-BCR/ABL antibody by PLGA nanoparticles suppresses the oncogenesis of chronic myeloid leukemia cells

(2021) Guoyun Jiang et al.   Journal of Hematology & Oncology

TRIM21/Ro52 - Roles in Innate Immunity and Autoimmune Disease

(2021) Esther L. Jones et al.   Frontiers in Immunology

Local delivery strategies to restore immune homeostasis in the context of inflammation

(2021) Elizabeth R. Bentley et al.   ADVANCED DRUG DELIVERY REVIEWS

Effects of Mesenchymal Stem Cell-Derived Exosomes on Autoimmune Diseases

(2021) Ziwei Shen et al.   Frontiers in Immunology

A baicalin-loaded coaxial nanofiber scaffold regulated inflammation and osteoclast differentiation for vascularized bone regeneration

(2021) Shue Jin et al.   Bioactive Materials

CME Part II: Immune checkpoint inhibitor-related dermatologic adverse events

(2020) Amaris N. Geisler et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Activation of the interleukin-23/interleukin-17 signalling pathway in autoinflammatory and autoimmune uveitis

(2020) Zhenyu Zhong et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Gold Nanoparticles for Drug Delivery and Cancer Therapy

(2020) Sarkar Siddique et al.   Applied Sciences-Basel

Quality of life in patients with uveitis: data from the ULISSE study (Uveitis: cLInical and medico-economic evaluation of a Standardised Strategy for the Etiological diagnosis)

(2020) Pierre-jean Bertrand et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Application of Nanomaterials in Biomedical Imaging and Cancer Therapy

(2020) Sarkar Siddique et al.   Nanomaterials

Pyruvate kinase M2 (PKM2) in cancer and cancer therapeutics

(2020) Susi Zhu et al.   CANCER LETTERS

Retinoic acid‐induced autoantigen‐specific type 1 regulatory T cells suppress autoimmunity

(2019) Mathilde Raverdeau et al.   EMBO REPORTS

Intravenous sustained-release nifedipine ameliorates nonalcoholic fatty liver disease by restoring autophagic clearance

(2019) Solji Lee et al.   BIOMATERIALS

Depletion of PD-1-positive cells ameliorates autoimmune disease

(2019) Peng Zhao et al.   Nature Biomedical Engineering

Immunomodulatory Nanosystems

(2019) Xiangru Feng et al.   Advanced Science

A sequential targeting nanoplatform for anaplastic thyroid carcinoma theranostics

(2019) Qimeihui Wang et al.   Acta Biomaterialia

C‐MET–dependent signal transduction mediates retinoblastoma growth by regulating PKM2 nuclear translocation

(2019) Hanjun Dai et al.   CELL BIOCHEMISTRY AND FUNCTION

Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

(2019) Stefano Angiari et al.   Cell Metabolism

Unraveling the Complex Interplay Between T Cell Metabolism and Function

(2018) Ramon I. Klein Geltink et al.   Annual Review of Immunology

PKM2, a potential target for regulating cancer

(2018) Yu-huan Li et al.   GENE

Optimising drug therapy for non-infectious uveitis

(2018) Mohammad Ali Shahab et al.   INTERNATIONAL OPHTHALMOLOGY

The Role of IFN-alpha in Experimental and Clinical Uveitis

(2017) Xiaoli Liu et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

A Novel High Mechanical Property PLGA Composite Matrix Loaded with Nanodiamond–Phospholipid Compound for Bone Tissue Engineering

(2016) Fan Zhang et al.   ACS Applied Materials & Interfaces

Roles of interleukin-17 in uveitis

(2016) MartaCatarina Esteves Guedes et al.   INDIAN JOURNAL OF OPHTHALMOLOGY

Corrigendum to “Surface modification of electrospun PLGA scaffold with collagen for bioengineered skin substitutes” [J. Mater. Sci. Eng. C 66 (2016) 130–137]

(2016) A.R. Sadeghi et al.   Materials Science & Engineering C-Materials for Biological Applications

Paracrine co-delivery of TGF-β and IL-2 using CD4-targeted nanoparticles for induction and maintenance of regulatory T cells

(2015) Michael D. McHugh et al.   BIOMATERIALS

PKM2 contributes to cancer metabolism

(2015) Nicholas Wong et al.   CANCER LETTERS

Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation

(2015) Sophia Y. Lunt et al.   MOLECULAR CELL

MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis

(2015) Wen Pan et al.   Nature Communications

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

(2012) Dimitrios Anastasiou et al.   Nature Chemical Biology

Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets

(2011) R. D. Michalek et al.   JOURNAL OF IMMUNOLOGY

The PD-1 pathway in tolerance and autoimmunity

(2010) Loise M. Francisco et al.   IMMUNOLOGICAL REVIEWS

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal

(2009) Brian T Fife et al.   NATURE IMMUNOLOGY

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

(2008) Dror Luger et al.   JOURNAL OF EXPERIMENTAL MEDICINE