Gardenia jasminoides Ellis polysaccharide ameliorates cholestatic liver injury by alleviating gut microbiota dysbiosis and inhibiting the TLR4/NF-κB signaling pathway

Network pharmacology based research into the effect and mechanism of Yinchenhao Decoction against Cholangiocarcinoma

(2021) Zhiqiang Chen et al.   Chinese Medicine

Protection of surface layer protein from Enterococcus faecium WEFA23 against Listeria monocytogenes CMCC54007 infection by modulating intestinal permeability and immunity

(2021) Yao He et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Lycium barbarum polysaccharide combined with aerobic exercise ameliorated nonalcoholic fatty liver disease through restoring gut microbiota, intestinal barrier and inhibiting hepatic inflammation

(2021) Lu-Lu Gao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Gut Microbiota and Its Metabolite Deoxycholic Acid Contribute to Sucralose Consumption-Induced Nonalcoholic Fatty Liver Disease

(2021) Zunji Shi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Time-series metabolomics insights into the progressive characteristics of 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestatic liver fibrosis in mice

(2021) Yuanyuan Li et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Cholestatic Liver Disease: Current Treatment Strategies and New Therapeutic Agents

(2021) Sho Hasegawa et al.   DRUGS

Walnut green husk polysaccharides prevent obesity, chronic inflammatory responses, nonalcoholic fatty liver disease and colonic tissue damage in high-fat diet fed rats

(2021) Guoliang Wang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The Role of Short-Chain Fatty Acids and Bile Acids in Intestinal and Liver Function, Inflammation, and Carcinogenesis

(2021) Alexander Visekruna et al.   Frontiers in Cell and Developmental Biology

Mori Fructus Polysaccharides Attenuate Alcohol-Induced Liver Damage by Regulating Fatty Acid Synthesis, Degradation and Glycerophospholipid Metabolism in Mice

(2021) Liang Bian et al.   Frontiers in Pharmacology

Targeting the Gut Microbiome as a Treatment for Primary Sclerosing Cholangitis

(2020) Ayesha Shah et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Cyclocarya paliurus polysaccharide alleviates liver inflammation in mice via beneficial regulation of gut microbiota and TLR4/MAPK signaling pathways

(2020) Ting Wu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Yinchenzhufu decoction protects against alpha-naphthylisothiocyanate-induced acute cholestatic liver injury in mice by ameliorating disordered bile acid homeostasis and inhibiting inflammatory responses

(2020) Guo-Feng Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Puerarin Increases Survival and Protects Against Organ Injury by Suppressing NF-κB/JNK Signaling in Experimental Sepsis

(2020) Lei Wang et al.   Frontiers in Pharmacology

Contribution of the Intestinal Microbiome and Gut Barrier to Hepatic Disorders

(2020) Daniel M. Chopyk et al.   GASTROENTEROLOGY

Gardenia jasminoides Ellis: Ethnopharmacology, phytochemistry, and pharmacological and industrial applications of an important traditional Chinese medicine

(2020) Liping Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

An update on the management of cholestatic liver diseases

(2020) Gautham Appanna et al.   CLINICAL MEDICINE

Role of gut microbiota in identification of novel TCM-derived active metabolites

(2020) Tzu-Lung Lin et al.   Protein & Cell

Altered gut microbial metabolism of essential nutrients in primary sclerosing cholangitis

(2020) Martin Kummen et al.   GASTROENTEROLOGY

Lactobacillus plantarum KLDS1.0344 and Lactobacillus acidophilus KLDS1.0901 Mixture Prevents Chronic Alcoholic Liver Injury in Mice by Protecting the Intestinal Barrier and Regulating Gut Microbiota and Liver-Related Pathways

(2020) Huizhen Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hepatoprotective effects of Huangqi decoction (Astragali Radix and Glycyrrhizae Radix et Rhizoma) on cholestatic liver injury in mice: Involvement of alleviating intestinal microbiota dysbiosis

(2020) Juan Zou et al.   JOURNAL OF ETHNOPHARMACOLOGY

Gut-Liver Axis, Gut Microbiota, and Its Modulation in the Management of Liver Diseases: A Review of the Literature

(2019) Ivana Milosevic et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis

(2019) Nobuhiro Nakamoto et al.   Nature Microbiology

Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis

(2019) Lijun Liao et al.   GUT

Comprehensive Analysis of Serum and Fecal Bile Acid Profiles and Interaction with Gut Microbiota in Primary Biliary Cholangitis

(2019) Weihua Chen et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Fecal Microbiota Transplantation in Patients With Primary Sclerosing Cholangitis

(2019) Jessica R. Allegretti et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Fungi participate in the dysbiosis of gut microbiota in patients with primary sclerosing cholangitis

(2019) Sara Lemoinne et al.   GUT

Probiotic LGG prevents liver fibrosis through inhibiting hepatic bile acid synthesis and enhancing bile acid excretion in mice

(2019) Yunhuan Liu et al.   HEPATOLOGY

Mushroom polysaccharides and jiaogulan saponins exert cancer preventive effects by shaping the gut microbiota and microenvironment in Apc mice

(2019) Imran Khan et al.   PHARMACOLOGICAL RESEARCH

Characterization of organic anion transporting polypeptide 1b2 knockout rats generated by CRISPR/Cas9: a novel model for drug transport and hyperbilirubinemia disease

(2019) Xinrun Ma et al.   Acta Pharmaceutica Sinica B

Quantitative Proteomics Reveals the Protective Effects of Huangqi Decoction Against Acute Cholestatic Liver Injury by Inhibiting the NF-κB/IL-6/STAT3 Signaling Pathway

(2019) Jia-Sheng Wu et al.   JOURNAL OF PROTEOME RESEARCH

Structural features of a new water-soluble polysaccharide from the gum exudates of Amygdalus scoparia Spach (Zedo gum)

(2018) Hamideh Molaei et al.   CARBOHYDRATE POLYMERS

Angelica sinensis polysaccharide protects against acetaminophen-induced acute liver injury and cell death by suppressing oxidative stress and hepatic apoptosis in vivo and in vitro

(2018) Peng Cao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy

(2017) Ruqi Tang et al.   GUT

Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis

(2017) Wei Jia et al.   Nature Reviews Gastroenterology & Hepatology

Huangqi Decoction Alleviates Alpha-Naphthylisothiocyanate Induced Intrahepatic Cholestasis by Reversing Disordered Bile Acid and Glutathione Homeostasis in Mice

(2017) Jia-Sheng Wu et al.   Frontiers in Pharmacology

Alterations and correlations of the gut microbiome, metabolism and immunity in patients with primary biliary cirrhosis

(2016) Long-Xian Lv et al.   ENVIRONMENTAL MICROBIOLOGY

The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls

(2016) Martin Kummen et al.   GUT

Polysaccharide Degradation by the Intestinal Microbiota and Its Influence on Human Health and Disease

(2016) Darrell W. Cockburn et al.   JOURNAL OF MOLECULAR BIOLOGY

A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis

(2016) Frederik Nevens et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of farnesoid X receptor in establishment of ontogeny of phase-I drug metabolizing enzyme genes in mouse liver

(2016) Lai Peng et al.   Acta Pharmaceutica Sinica B

Fenofibrate is effective adjunctive therapy in the treatment of primary biliary cirrhosis: A meta-analysis

(2015) Alla Y. Grigorian et al.   Clinics and Research in Hepatology and Gastroenterology