Article
Neurosciences
Kaitlin B. Casaletto, Cutter A. Lindbergh, Anna VandeBunte, John Neuhaus, Julie A. Schneider, Aron S. Buchman, William G. Honer, David A. Bennett
Summary: Physical activity may reduce the risk of dementia by decreasing microglial activation and promoting synaptic and cognitive resilience. This study demonstrated a causal link between physical activity and microglial homeostasis in humans and found that lower microglial activation may be a pathway linking physical activity to age-related brain health.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Maya Baughn, Victor Arellano, Brieanna Hawthorne-Crosby, Joseph S. Lightner, Amanda Grimes, Gregory King
Summary: Falling is a critical health issue among older adults, and cycling may be an effective intervention to prevent falls. This study objectively measured the relationship between cycling, physical activity, and balance for older adults and found that older adult cyclists exhibited better physical activity, balance, and stability.
Article
Multidisciplinary Sciences
Nils Georg Niederstrasser, Nina Attridge
Summary: The study found that high levels of physical activity were associated with a reduced risk of suffering from musculoskeletal pain. In addition, low wealth, being female, and being overweight or obese were identified as risk factors for musculoskeletal pain.
Article
Multidisciplinary Sciences
Robert J. Dawe, Lei Yu, Sue E. Leurgans, Bryan D. James, Victoria N. Poole, Konstantinos Arfanakis, Julie A. Schneider, David A. Bennett, Aron S. Buchman
Summary: Postmortem MRI can capture brain tissue characteristics that mediate the association between physical activity and cognition in older adults. Two R-2 components partially mediated the relationship between physical activity and cognition, accounting for 12.7% of the association. Further studies are needed to elucidate the molecular mechanisms underlying this pathway.
Review
Rehabilitation
Davy Vancampfort, Tine Van Damme, Joseph Firth, Brendon Stubbs, Felipe Schuch, Shuichi Suetani, Anke Arkesteyn, Debbie Van Biesen
Summary: Despite ample evidence of the benefits of physical activity for people with intellectual disabilities, only three consistent correlates were identified for adults with ID. No consistent correlates were found for children, adolescents, and older adults. Further research, particularly among young and older populations, is urgently needed.
DISABILITY AND REHABILITATION
(2022)
Article
Environmental Studies
Lanjing Wang, Xiayidan Xiaohelaiti, Yi Zhang, Xiaofei Liu, Xumei Chen, Chaoyang Li, Tao Wang, Jiani Wu
Summary: This study investigated the relationship between the built and social environment and the gender differences in cycling frequency among older urban adults in China. The results suggest that denser intersections are negatively related to cycling trips among both older men and women. Reverse associations for either gender, however, are observed between the average income in a neighborhood and cycling frequency. For older women, living far from a bus stop is positively correlated to an increase in daily cycling trips. For older men, social environment, including the proportions of employed or elderly people in a neighborhood, is significantly associated with cycling activity.
Article
Geriatrics & Gerontology
Daniel R. Sokolowski, Tor I. Hansen, Henning H. Rise, Line S. Reitlo, Ulrik Wisloff, Dorthe Stensvold, Asta K. Haberg
Summary: In a 5-year study on older adults investigating the effects of aerobic exercise interventions on cognition, high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) did not show superior cognitive performance compared to following national physical activity guidelines. Higher cardiorespiratory fitness (CRF) was associated with better processing speed, while increasing CRF during the intervention was linked to improved working memory and poorer pattern separation.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Review
Psychiatry
Su Zhang, Kun Xiang, Shujing Li, Hai-Feng Pan
Summary: This study provides a comprehensive review of the relationship between physical activity and depression in older adults, showing a clear inverse relationship. Physical activity is considered a promising nonpharmaceutical method in treating and preventing depression in older adults.
PSYCHIATRY RESEARCH
(2021)
Article
Clinical Neurology
Oliver Vogel, Daniel Niederer, Jan Wilke, Inaam El-Rajab, Lutz Vogt
Summary: There is no direct association between physical activity levels and sleep quality in older adults. However, a shorter sleep duration of 5 to 6 hours was associated with higher levels of physical activity.
FRONTIERS IN NEUROLOGY
(2021)
Article
Multidisciplinary Sciences
Manish Kumar, Shobhit Srivastava, T. Muhammad
Summary: In India, frequent physical activity is positively associated with cognitive functioning among older adults, regardless of gender. This association holds true after controlling for various potential factors.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Seongryu Bae, Minwoo Jang, Gwon-Min Kim, Ja-Gyeong Yang, Ngeemasara Thapa, Hye-Jin Park, Hyuntae Park
Summary: This study examines the relationship between physical function, physical activity, sleep, and depressive symptoms in older adults. The results show that the Six-Minute Walk Test, gait speed, and moderate-to-vigorous physical activity exhibit a nonlinear relationship with depressive symptoms, while other physical functions show a linear relationship. Sleep time follows a U-shaped trend starting at approximately 390 minutes. After adjusting for various factors, the Six-Minute Walk Test, moderate-to-vigorous physical activity, and sleep time are significantly associated with depressive symptoms.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Nanyan Li, Qin Ye, Qian Deng, Yufei Wang, Julinling Hu, Xianlan Li, Qianqian Liu, Meili Jiang, Xing Zhao, Junmin Zhou
Summary: In a cluster randomized trial conducted in China, a multilevel intervention significantly increased leisure-time activity levels in older adults for a period of 24 months, suggesting that similar interventions could be effective in tackling physical inactivity in older adults in low- and middle-income countries.
Article
Public, Environmental & Occupational Health
Emily You, Nicola T. Lautenschlager, Ching Shan Wan, Anita M. Y. Goh, Eleanor Curran, Terence W. H. Chong, Kaarin J. Anstey, Fahad Hanna, Kathryn A. Ellis
Summary: Older Caucasian and Chinese adults have similar views on the benefits and barriers to physical activity, with main barriers including health issues, costs, weather, and lack of time, and enablers including improving health, a conducive environment, and peer support. Older Chinese adults report barriers more frequently and have unique barriers related to language and culture issues. The findings contribute to developing targeted physical activity programs for older Caucasian and Chinese adults.
FRONTIERS IN PUBLIC HEALTH
(2021)
Review
Nutrition & Dietetics
Jennifer Taylor, Sarah Walsh, Wing Kwok, Marina B. Pinheiro, Juliana Souza de Oliveira, Leanne Hassett, Adrian Bauman, Fiona Bull, Anne Tiedemann, Catherine Sherrington
Summary: The scoping review investigated the evidence on physical activity interventions among adults aged 60+, identifying gaps in existing research and the need for further studies to explore interventions designed to increase physical activity in older adults. While there is a growing volume of evidence for certain interventions, there are still areas lacking coverage and requiring more comprehensive reviews and research.
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY
(2021)
Article
Nutrition & Dietetics
Javier Conde-Pipo, Cristina Bouzas, Felix Zurita-Ortega, Fatima Olea-Serrano, Josep A. Tur, Miguel Mariscal-Arcas
Summary: The study found that non-adherence to the Mediterranean dietary pattern and low levels of physical activity are associated with lower levels of physical self-concept in older adults.
Article
Sport Sciences
Hallgeir Viken, Line Skarsem Reitlo, Nina Zisko, Javaid Nauman, Nils Petter Aspvik, Jan Erik Ingebrigtsen, Ulrik Wisloff, Dorthe Stensvold
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2019)
Article
Cardiac & Cardiovascular Systems
Ross Arena, Jonathan Myers, Mathew Harber, Ulrik Wisloff, Dorthe Stensvold, Leonard A. Kaminsky
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2020)
Article
Medicine, General & Internal
James E. Peterman, Ross Arena, Jonathan Myers, Susan Marzolini, Robert Ross, Carl J. Lavie, Ulrik Wisloff, Dorthe Stensvold, Leonard A. Kaminsky
MAYO CLINIC PROCEEDINGS
(2020)
Review
Cardiac & Cardiovascular Systems
Anja Bye, Marie Klevjer, Einar Ryeng, Gustavo Jose Justo da Silva, Jose Bianco Nascimento Moreira, Dorthe Stensvold, Ulrik Wisloff
PROGRESS IN CARDIOVASCULAR DISEASES
(2020)
Article
Rheumatology
Marthe Halsan Liff, Mari Hoff, Ulrik Wisloff, Vibeke Videm
Summary: The study aimed to compare the change in estimated cardiorespiratory fitness in rheumatoid arthritis patients with controls over an 11-year follow-up period. Results showed that the decline in fitness was faster in RA patients and associated with factors like age, smoking, and cardiovascular disease.
RHEUMATOLOGY INTERNATIONAL
(2021)
Article
Medicine, General & Internal
Javaid Nauman, Barry A. Franklin, Bjarne M. Nes, Robert E. Sallis, Susumu S. Sawada, Jasna Marinovic, Dorthe Stensvold, Carl J. Lavie, Atefe R. Tari, Ulrik Wisloff
Summary: This study aimed to investigate the association between personal activity intelligence (PAI) and mortality in relatively healthy participants in China. The results showed that higher PAI scores were associated with a lower risk of cardiovascular disease and all-cause mortality, and the subgroup with a PAI score greater than or equal to 100 gained a longer life expectancy compared to the inactive cohort.
MAYO CLINIC PROCEEDINGS
(2022)
Article
Cardiac & Cardiovascular Systems
Benedikte Therese Smenes, Bjarne Martens Nes, Jon Magne Letnes, Katrine Hordnes Slagsvold, Ulrik Wisloff, Alexander Wahba
Summary: Low physical activity and cardiorespiratory fitness are risk factors for coronary artery disease. Our study found that high levels of physical activity and cardiorespiratory fitness were associated with a lower risk of coronary surgery and lower overall mortality after surgery.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Medicine, General & Internal
Henrik Loe, Mats Peder Mosti, Ulrik Wisloff, Carolin Haberstroh, Grete Flemmen
Summary: This study aims to compare the effect of low-dose and high-dose, high-intensity training on physical fitness in patients diagnosed with substance use disorder (SUD). The study will recruit 40 in-patients and include high-intensity interval and maximal strength training sessions. The findings of this study will contribute to understanding the ideal training dose required to improve physical fitness in patients with SUD.
Article
Cardiac & Cardiovascular Systems
Elisabeth Kleivhaug Vesterbekkmo, Inger-Lise Aamot Aksetoy, Turid Follestad, Hans Olav Nilsen, Knut Hegbom, Ulrik Wisloff, Rune Wiseth, Erik Madssen
Summary: This study investigated the changes in coronary plaque geometry in stable coronary artery disease patients after 6 months of supervised high-intensity interval training (HIIT). The results showed a reduction in plaque volume and number after HIIT. Therefore, it can be concluded that HIIT can inhibit the progression of coronary plaques and is of significant importance in the prevention of coronary artery disease.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Geriatrics & Gerontology
Line S. Reitlo, Jelena M. Mihailovic, Dorthe Stensvold, Ulrik Wisloff, Fahmeed Hyder, Asta Kristine Haberg
Summary: The study aimed to investigate the differences in hippocampal metabolites for neuronal viability and cell membrane density between older adults performing supervised exercise and those following national physical activity guidelines. The results showed that supervised exercise led to lower NAA/Cr levels in the hippocampal body compared to following guidelines. Higher training intensity was associated with lower Cho/Cr levels in the hippocampal body. Lower NAA/Cr levels were associated with poorer psychological health and slightly higher cognitive scores. Following national guidelines and not training at the highest intensity level resulted in the best neurochemical profile in the hippocampus at 3 years.
Article
Cardiac & Cardiovascular Systems
Jon Magne Letnes, Bjarne Martens Nes, Knut Asbjorn Rise Langlo, Inger-Lise Aamot Aksetoy, Kari Margrethe Lundgren, Knut Skovereng, Oyvind Sandbakk, Ulrik Wisloff, Havard Dalen
Summary: The study found that indexing left ventricular end-diastolic volume (LVEDV) and left atrial maximal volume (LAVmax) by body surface area (BSA) does not accurately reflect cardiovascular adaptations to metabolic demands. Indexing LVEDV to absolute peak oxygen uptake (VO2peak) and fat-free mass (FFM) improves differentiation between physiological and pathological remodeling. Indexing LVEDV to VO2peak enhances the classification ability in heart failure patients and athletes, while all indexing methods have low explanatory power for LAVmax.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Benedikte Therese Smenes Nystoyl, Jon Magne Letnes, Bjarne Martens Nes, Katrine Hordnes Slagsvold, Ulrik Wisloff, Alexander Wahba
Summary: The study found a strong and inverse relationship between estimated cardiorespiratory fitness and the incidence of AVR due to AVS. Higher estimated cardiorespiratory fitness was associated with lower postoperative mortality.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Karsten Ovretveit, Emma M. L. Ingestrom, Michail Spitieris, Vinicius Tragante, Kaitlin H. Wade, Laurent F. Thomas, Brooke N. Wolford, Ulrik Wisloff, Daniel F. Gudbjartsson, Hilma Holm, Kari Stefansson, Ben M. Brumpton, Kristian Hveem
Summary: This study examines the polygenic risk of hypertension in children and adults, and finds that genetic risk factors for blood pressure start affecting individuals from early life. These findings help identify high-risk individuals, enable primordial prevention, and reduce the burden of this public health challenge.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Review
Endocrinology & Metabolism
Jose B. N. Moreira, Martin Wohlwend, Ulrik Wisloff
