ManNAc protects against podocyte pyroptosis via inhibiting mitochondrial damage and ROS/NLRP3 signaling pathway in diabetic kidney injury model

Necroptosis, pyroptosis and apoptosis: an intricate game of cell death

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Hyperglycemia alters mitochondrial respiration efficiency and mitophagy in human podocytes

(2021) Irena Audzeyenka et al.   EXPERIMENTAL CELL RESEARCH

Carnosine alleviates podocyte injury in diabetic nephropathy by targeting caspase-1-mediated pyroptosis

(2021) Wei Zhu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hyposialylated angiopoietin-like-4 induces apoptosis of podocytes via β1 Integrin/FAK signaling in diabetic nephropathy

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Geniposide alleviates diabetic nephropathy of mice through AMPK/SIRT1/NF-κB pathway

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Calcineurin inhibitors ameliorate PAN ‐induced podocyte injury through the NFAT‐Angptl4 pathway

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Caspase-11/4 and gasdermin D-mediated pyroptosis contributes to podocyte injury in mouse diabetic nephropathy

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New Insights into the Mechanisms of Pyroptosis and Implications for Diabetic Kidney Disease

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Tim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-κB/TNF-α pathway

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Butyrated ManNAc analog improves protein expression in Chinese hamster ovary cells

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Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion

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Polydatin impairs mitochondria fitness and ameliorates podocyte injury by suppressing Drp1 expression

(2017) Zheng Ni et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mitochondrial energetics in the kidney

(2017) Pallavi Bhargava et al.   Nature Reviews Nephrology

The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity

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mTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes

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Notoginsenoside R1 ameliorates podocyte injury in rats with diabetic nephropathy by activating the PI3K/Akt signaling pathway

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Autophagy protects human podocytes from high glucose-induced injury by preventing insulin resistance

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Intraglomerular crosstalk elaborately regulates podocyte injury and repair in diabetic patients: insights from a 3D multiscale modeling study

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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Mitochondria in the Regulation of Innate and Adaptive Immunity

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Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy

(2015) Khurrum Shahzad et al.   KIDNEY INTERNATIONAL

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(2015) Sivapriya K. Vanaja et al.   TRENDS IN CELL BIOLOGY

Glomerular parietal epithelial cell activation induces collagen secretion and thickening of Bowman’s capsule in diabetes

(2014) Alexander Holderied et al.   LABORATORY INVESTIGATION

Reactive oxygen species at the crossroads of inflammasome and inflammation

(2014) Anantha Harijith et al.   Frontiers in Physiology

Angiopoietin-like Protein 4 Inhibition of Lipoprotein Lipase

(2013) Michael J. Lafferty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiinflammatory effects of apoptotic cells

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ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters

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Angiopoietin-like 4 Protein Elevates the Prosurvival Intracellular O2−:H2O2 Ratio and Confers Anoikis Resistance to Tumors

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Caspase-1-induced pyroptotic cell death

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Angiopoietin-Like 4 Interacts with Integrins β1 and β5 to Modulate Keratinocyte Migration

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Signaling pathways in mitochondrial dysfunction and aging

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Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome

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Caloric Restriction and Exercise Increase Plasma ANGPTL4 Levels in Humans via Elevated Free Fatty Acids

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