Article
Multidisciplinary Sciences
Hong Gao, Dong-e Liu, Yumei Li, Xinrui Wu, Hongzhuan Tan
Summary: The study aimed to establish and validate a live birth prediction model for ART patients, providing a reliable tool for obstetricians to predict the live birth rate of ART patients and creating good conditions for infertility patients in preparation for pregnancy.
SCIENTIFIC REPORTS
(2021)
Article
Obstetrics & Gynecology
Zheng Wang, Astrid E. P. Cantineau, Annemieke Hoek, Rik van Eekelen, Ben W. Mol, Rui Wang
Summary: In assisted reproductive technology (ART) research, live birth is considered an important outcome but its interpretation can be misleading when solely focused on. This review presents an overview of the definitions of live birth and demonstrates through clinical examples the impact of variations in live birth on research findings, highlighting the importance of considering other outcomes such as multiple pregnancy, pregnancy loss, and maternal and offspring health outcomes. A holistic outcome assessment beyond live birth is necessary to inform evidence-based decision making in ART research.
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Mustapha Benkhalifa, Fabien Joao, Cynthia Duval, Debbie Montjean, Molka Bouricha, Rosalie Cabry, Marie-Claire Belanger, Hatem Bahri, Pierre Miron, Moncef Benkhalifa
Summary: After more than four decades of assisted reproductive technology (ART) practice, the failure of in vitro fertilization (IVF) treatments and recurrent implantation failures (RIFs) and repeated pregnancy loss (RPL) remain significant issues. This article reviews different therapeutic options and suggests that immunomodulation and predictive biomarkers may be promising solutions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Obstetrics & Gynecology
Chloe Maignien, Pietro Santulli, Louis Marcellin, Diane Korb, Corinne Bordonne, Bertrand Dousset, Mathilde Bourdon, Charles Chapron
Summary: A prospective study on bowel endometriosis patients found that those who had not undergone surgery for endometriosis prior to ART treatment showed a satisfactory cumulative live-birth rate of 64.4%. The majority of these patients had associated endometriomas and adenomyosis.
FERTILITY AND STERILITY
(2021)
Article
Obstetrics & Gynecology
Georgina M. Chambers, Silke Dyer, Fernando Zegers-Hochschild, Jacques de Mouzon, Osamu Ishihara, Manish Banker, Ragaa Mansour, Markus S. Kupka, G. David Adamson
Summary: In 2014, 1.93 million ART cycles were performed in 76 countries, with trends showing increased success rates, frozen embryo transfer cycles, single embryo transfer, and preimplantation genetic testing. Utilization rates and effectiveness of ART continue to improve globally.
HUMAN REPRODUCTION
(2021)
Article
Environmental Sciences
Chuyue Zhang, Ning Yao, Yao Lu, Jingyi Ni, Xiaohui Liu, Ji Zhou, Wangsheng Wang, Ting Zhang, Yaqiong He, Jiaan Huang, Kang Sun, Yun Sun
Summary: This study reveals a negative association between air pollutant exposure before oocyte retrieval and livebirth rate in assisted reproductive technology (ART). The adverse impact is more evident in a one-year exposure window compared to the three-month refresh cycle. Women undergoing frozen embryo transfer cycles, especially those with two embryos transferred, are more vulnerable to air pollutant exposure.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Obstetrics & Gynecology
Manish Banker, Silke Dyer, Georgina M. Chambers, Osamu Ishihara, Markus Kupka, Jacques de Mouzon, Fernando Zegers-Hochschild, G. David Adamson
Summary: The report provides data on the utilization, effectiveness, and safety of assisted reproductive technology (ART) globally in 2013, showing an increase in ART cycles and changes in trends such as a rise in the proportion of older women undergoing non-donor ART. Further efforts are needed to improve the quality and consistency of reporting ART data by registries.
FERTILITY AND STERILITY
(2021)
Editorial Material
Oncology
Cock van Oosterhout, Daniel Marcu, Simone Immler
Summary: This article discusses the significant impact of genetic load on assisted reproductive technology, human reproduction, and fertility. It explores these topics in the context of evolutionary genetic theory, the technological revolution in ART, and the advancements in genomics and bioinformatics.
CLINICAL AND TRANSLATIONAL MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Anand Baby Alias, Hong-Yuan Huang, Da-Jeng Yao
Summary: Infertility refers to the inability to achieve pregnancy after 12 or more months of regular unprotected sexual intercourse. Assisted reproductive technology (ART) plays a crucial role in addressing infertility, with techniques like IVF, ICSI, and IUI being commonly used. Microfluidic technologies can enhance ART procedures by incorporating various techniques for analysis, manipulation, and monitoring of embryos and gametes.
Article
Surgery
Ezra S. Brooks, Catherine L. Mavroudis, Jason Tong, Christopher J. Wirtalla, Ari Friedman, Rachel R. Kelz
Summary: This study examines the role of hub-and-spoke systems in structural racism and discrimination. It finds that Black and Hispanic patients are less likely to be referred to hub hospitals compared with White patients, highlighting a potential health equity issue.
Article
Genetics & Heredity
Seung Chik Jwa, Akira Namba, Shunsuke Tamaru, Akira Kuwahara, Haruhiko Sago, Osamu Ishihara, Yoshimasa Kamei
Summary: This study found that the introduction of non-invasive prenatal testing (NIPT) balanced the prevalence of Down syndrome live births following assisted reproductive technology (ART) in Japan. The study also found that advanced maternal age was a contributing factor to the increase in Down syndrome live births.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2022)
Review
Nutrition & Dietetics
Nicole J. Kellow, Jake Le Cerf, Fabrizzio Horta, Aimee L. Dordevic, Christie J. Bennett
Summary: The impact of dietary patterns on pregnancy outcomes in individuals using assisted reproductive technologies (ARTs) is currently unknown. This review synthesized published research and found that certain dietary patterns were associated with increased likelihood of clinical pregnancy and live birth. However, the included studies had a moderate-high risk of bias, highlighting the need for higher-quality research in this field.
ADVANCES IN NUTRITION
(2022)
Editorial Material
Obstetrics & Gynecology
Marcelle I. Cedars
Summary: Artificial intelligence involves the use of a computer that can perform human functions, such as learning from experience, adjusting to new inputs, and simulating human intelligence performing tasks. This article brings together a diverse group of investigators to evaluate the roles that artificial intelligence might play in assisted reproductive technology.
FERTILITY AND STERILITY
(2023)
Article
Pharmacology & Pharmacy
Xiaoyan Lu, Yiying Sun, Meishan Han, Daoyuan Chen, Xiaoyan He, Siqi Wang, Kaoxiang Sun
Summary: We report silk fibroin-based microneedles for transdermal delivery of triptorelin-loaded nanoparticles to improve bioavailability and self-administration of triptorelin. The developed microneedles showed good mechanical properties and increased transdermal release of triptorelin, indicating their potential therapeutic role in assisted reproductive technology regimens.
Article
Endocrinology & Metabolism
Youzhen Zhang, Wei Zhou, Wanbing Feng, Jingmei Hu, Kuona Hu, Linlin Cui, Zi-Jiang Chen
Summary: The study found that assisted reproductive technology (ART) treatment may amplify the adverse effect of female infertility on neonates. Women with tubal factor infertility, ovulatory dysfunction, and unexplained infertility have a higher risk of preterm birth after ART treatment.
FRONTIERS IN ENDOCRINOLOGY
(2022)
