Exenatide ameliorates hydrogen peroxide-induced pancreatic β-cell apoptosis through regulation of METTL3-mediated m6A methylation

The Role of Oxidative Stress in Pancreatic β Cell Dysfunction in Diabetes

(2021) Natsuki Eguchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

METTL3 is required for maintaining β-cell function

(2021) Xinzhi Li et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Targeting oxidative stress in disease: promise and limitations of antioxidant therapy

(2021) Henry Jay Forman et al.   NATURE REVIEWS DRUG DISCOVERY

IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045

(2021) Hong Sun et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

m6A mRNA Methylation Controls Functional Maturation in Neonatal Murine β Cells

(2020) Yanqiu Wang et al.   DIABETES

Preparation, characterization and in vitro–in vivo evaluation of bortezomib supermolecular aggregation nanovehicles

(2020) Ming-yue Chen et al.   JOURNAL OF NANOBIOTECHNOLOGY

Targeting inhibition of CCR5 on improving obesity-associated insulin resistance and impairment of pancreatic insulin secretion in high fat-fed rodent models

(2020) Pei-Chi Chan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

METTL14 is essential for β-cell survival and insulin secretion

(2019) Jun Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

LncRNA LEGLTBC Functions as a ceRNA to Antagonize the Effects of miR-34a on the Downregulation of SIRT1 in Glucolipotoxicity-Induced INS-1 Beta Cell Oxidative Stress and Apoptosis

(2019) Xiang Kong et al.   Oxidative Medicine and Cellular Longevity

Glucose is involved in the dynamic regulation of m6A in patients with type 2 diabetes

(2018) Ying Yang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The PI3K/Akt1-FoxO1 Translocation Pathway Mediates EXf Effects on NIT-1 Cell Survival

(2017) Guo-jiang Hou et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Most m6A RNA Modifications in Protein-Coding Regions Are Evolutionarily Unconserved and Likely Nonfunctional

(2017) Zhen Liu et al.   MOLECULAR BIOLOGY AND EVOLUTION

Oxidative Stress in Pancreatic Beta Cell Regeneration

(2017) Jingjing Wang et al.   Oxidative Medicine and Cellular Longevity

EX4 stabilizes and activates Nrf2 via PKCδ, contributing to the prevention of oxidative stress-induced pancreatic beta cell damage

(2017) Mi-Hwi Kim et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

(2016) Shuibin Lin et al.   MOLECULAR CELL

DecreasedN6-Methyladenosine in Peripheral Blood RNA From Diabetic Patients Is Associated WithFTOExpression Rather ThanALKBH5

(2015) Fan Shen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

Emerging Roles of RNA Modification: m 6 A and U-Tail

(2014) Mihye Lee et al.   CELL

m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells

(2014) Pedro J. Batista et al.   Cell Stem Cell

Advances in the cellular immunological pathogenesis of type 1 diabetes

(2014) Min Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Gene expression regulation mediated through reversible m6A RNA methylation

(2014) Ye Fu et al.   NATURE REVIEWS GENETICS

RNA-Methylation-Dependent RNA Processing Controls the Speed of the Circadian Clock

(2013) Jean-Michel Fustin et al.   CELL

Role of Reduced  -Cell Mass Versus Impaired  -Cell Function in the Pathogenesis of Type 2 Diabetes

(2013) J. J. Meier et al.   DIABETES CARE

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Exendin-4 Protects Oxidative Stress-Induced β-Cell Apoptosis through Reduced JNK and GSK3β Activity

(2010) Ju-Young Kim et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

The effects of glucagon-like peptide-1 on the beta cell

(2009) T. Vilsbøll   DIABETES OBESITY & METABOLISM