Downregulation of connexin 43 potentiates amitriptyline-induced brain-derived neurotrophic factor expression in primary astrocytes through lysophosphatidic acid receptor1/3, Src, and extracellular signal-regulated kinase

Downregulation of connexin43 potentiates noradrenaline‐induced expression of brain‐derived neurotrophic factor in primary cultured cortical astrocytes

(2021) Norimitsu Morioka et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Reduced cerebrospinal fluid levels of lysophosphatidic acid docosahexaenoic acid (LPA-DHA) in patients with major depressive disorder and schizophrenia

(2021) Wataru Omori et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Genetic and pharmacological inactivation of astroglial connexin 43 differentially influences the acute response of antidepressant and anxiolytic drugs

(2020) Benjamin Portal et al.   Acta Physiologica

Connexin43 Region 266–283, via Src Inhibition, Reduces Neural Progenitor Cell Proliferation Promoted by EGF and FGF-2 and Increases Astrocytic Differentiation

(2020) Rocío Talaverón et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cx43 and the Actin Cytoskeleton: Novel Roles and Implications for Cell-Cell Junction-Based Barrier Function Regulation

(2020) Randy E. Strauss et al.   Biomolecules

Chronic central modulation of LPA/LPA receptors-signaling pathway in the mouse brain regulates cognition, emotion, and hippocampal neurogenesis

(2020) Cristina Rosell-Valle et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The ERK Pathway: Molecular Mechanisms and Treatment of Depression

(2019) John Q. Wang et al.   MOLECULAR NEUROBIOLOGY

Reduced Serum and Cerebrospinal Fluid Levels of Autotaxin in Major Depressive Disorder

(2019) Kei Itagaki et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Mirtazapine increases glial cell line-derived neurotrophic factor production through lysophosphatidic acid 1 receptor-mediated extracellular signal-regulated kinase signaling in astrocytes

(2019) Kazue Hisaoka-Nakashima et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

NMDAR-independent, cAMP-dependent antidepressant actions of ketamine

(2018) Nathan H. Wray et al.   MOLECULAR PSYCHIATRY

Gap junction channels as potential targets for the treatment of major depressive disorder

(2017) Qian Ren et al.   PSYCHOPHARMACOLOGY

Amitriptyline induces brain-derived neurotrophic factor (BDNF) mRNA expression through ERK-dependent modulation of multiple BDNF mRNA variants in primary cultured rat cortical astrocytes and microglia

(2016) Kazue Hisaoka-Nakashima et al.   BRAIN RESEARCH

Identification of Lysophosphatidic Acid Receptor 1 in Astroglial Cells as a Target for Glial Cell Line-derived Neurotrophic Factor Expression Induced by Antidepressants

(2016) Naoto Kajitani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast-acting antidepressants rapidly stimulate ERK signaling and BDNF release in primary neuronal cultures

(2016) Ashley E. Lepack et al.   NEUROPHARMACOLOGY

Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes

(2016) Ana González-Sánchez et al.   Oncotarget

Posttranslational modification of E-cadherin by core fucosylation regulates Src activation and induces epithelial–mesenchymal transition-like process in lung cancer cells

(2015) Kang Shao et al.   GLYCOBIOLOGY

Tricyclic Antidepressant Amitriptyline-induced Glial Cell Line-derived Neurotrophic Factor Production Involves Pertussis Toxin-sensitive Gαi/oActivation in Astroglial Cells

(2015) Kazue Hisaoka-Nakashima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of high-mobility group box 1 in methamphetamine-induced activation and migration of astrocytes

(2015) Yuan Zhang et al.   Journal of Neuroinflammation

Amitriptyline up-regulates connexin43-gap junction in rat cultured cortical astrocytes via activation of the p38 and c-Fos/AP-1 signalling pathway

(2014) N Morioka et al.   BRITISH JOURNAL OF PHARMACOLOGY

LPA receptor signaling: pharmacology, physiology, and pathophysiology

(2014) Yun C. Yung et al.   JOURNAL OF LIPID RESEARCH

Tricyclic Antidepressant Amitriptyline Indirectly Increases the Proliferation of Adult Dentate Gyrus-Derived Neural Precursors: An Involvement of Astrocytes

(2013) Shuken Boku et al.   PLoS One

Reduced connexin43 expression correlates with c-Src activation, proliferation, and glucose uptake in reactive astrocytes after an excitotoxic insult

(2012) Ester Gangoso et al.   GLIA

Antidepressant Acts on Astrocytes Leading to an Increase in the Expression of Neurotrophic/Growth Factors: Differential Regulation of FGF-2 by Noradrenaline

(2012) Naoto Kajitani et al.   PLoS One

Gap Junction Dysfunction in the Prefrontal Cortex Induces Depressive-Like Behaviors in Rats

(2011) Jian-Dong Sun et al.   NEUROPSYCHOPHARMACOLOGY

Altered expression of glutamate signaling, growth factor and glia genes in the locus coeruleus of patients with major depression

(2010) R Bernard et al.   MOLECULAR PSYCHIATRY

Modulation of connexin 43 in rotenone-induced model of Parkinson's disease

(2009) A. Kawasaki et al.   NEUROSCIENCE