期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 75, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2022.102716
关键词
-
资金
- National Natural Science Foundation of China [32100101, 92051103]
Biofilm formation by microbes on cultural heritage materials can lead to deterioration, especially in tropical and humid environments. Future research should focus on metabolically active microorganisms and biochemical reactions using a combination of methods, to improve our understanding of biofilm-mediated deterioration processes.
Microbial colonization and development into biofilms on cultural heritage have significant implications for the deterioration of materials, particularly in the tropic and humid environments. To advance the fundamental knowledge on the biofilm-mediated (bio)deterioration processes, future investigations must focus more on the metabolically active microorganisms and biochemical reactions by a combination of methods available. Newly accessible culture-independent techniques of highthroughput sequencing and multi-omics can be coupled with culture-dependent ones and specific biochemical assays, including stable isotopes and DNA probing. Here, we describe the recent advances on this subject matter, highlight a systematic analytical approach for an integrative diagnosis of `microbial diseases' of cultural heritage, and provide future prospects for a new paradigm of research on microbial biodeterioration of heritage materials.
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