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Sodium alginate based drug delivery in management of breast cancer

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CARBOHYDRATE POLYMERS
卷 292, 期 -, 页码 -

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ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2022.119689

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Sodium alginate; Breast cancer; Polysaccharides; Drug carrier; Signaling pathway

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Breast cancer is a common disease among women worldwide, and sodium alginate as a drug carrier shows potential for treating breast cancer.
Among women, breast cancer (B.C.) is a common form of cancer that can strike either developed or developing countries. In addition to pregnancy-related variables, hormone therapy lifestyle factors (e.g., physical inactivity, smoking, and alcohol use) may all influence the progression of B.C. The creation of anti-B.C. medication carriers with better stability, controlled and targeted administration, and the goal of minimizing unwanted effects has taken a lot of time and effort. Naturally generated biopolymers-based pharmaceutical delivery techniques have attracted attention for their potential use in treating B.C. It's been shown that natural polymers can deliver high medication concentrations to the desired place and provide prolonged release of pharmaceuticals useful in treating B.C. Alginate is one of the most commonly used drug carriers for delayed and targeted release. In present review will discuss the utilization of sodium alginate as an carrier of anticancer drug, such as paclitaxel, doxorubicin, tamoxifen, curcumin, and others.

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