Article
Medicine, General & Internal
William F. Fearon, Frederik M. Zimmermann, Bernard De Bruyne, Zsolt Piroth, Albert H. M. van Straten, Laszlo Szekely, Giedrius Davidavicius, Gintaras Kalinauskas, Samer Mansour, Rajesh Kharbanda, Nikolaos Ostlund-Papadogeorgos, Adel Aminian, Keith G. Oldroyd, Nawwar Al-Attar, Nikola Jagic, Jan-Henk E. Dambrink, Petr Kala, Oskar Angeras, Philip MacCarthy, Olaf Wendler, Filip Casselman, Nils Witt, Kreton Mavromatis, Steven E. S. Miner, Jaydeep Sarma, Thomas Engstrom, Evald H. Christiansen, Pim A. L. Tonino, Michael J. Reardon, Di Lu, Victoria Y. Ding, Yuhei Kobayashi, Mark A. Hlatky, Kenneth W. Mahaffey, Manisha Desai, Y. Joseph Woo, Alan C. Yeung, Nico H. J. Pijls
Summary: In this study, FFR-guided PCI for patients with three-vessel coronary artery disease was not found to be noninferior to CABG in terms of the occurrence of a composite of death, myocardial infarction, stroke, or repeat revascularization within 1 year.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Review
Medicine, General & Internal
Laurent Faroux, Aurelien Villecourt, Damien Metz, Michel Noutsias, Emmanuel Andres
Summary: About half of TAVR recipients have some degree of coronary artery disease (CAD), and controversial results exist regarding the impact of CAD on clinical outcomes post-TAVR. Recent data suggests promising results on the use of cardiac computed tomography angiography and functional invasive assessment of coronary lesions in the pre-TAVR work-up.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Krishnaraj S. Rathod, Katrina Comer, Oliver Casey-Gillman, Lizzie Moore, Gordon Mills, Gordon Ferguson, Sotiris Antoniou, Riyaz Patel, Sadeer Fhadil, Tasleem Damani, Paul Wright, Mick Ozkor, Debashish Das, Oliver P. Guttmann, Andreas Baumbach, R. Andrew Archbold, Andrew Wragg, Ajay K. Jain, Fizzah A. Choudry, Anthony Mathur, Daniel A. Jones
Summary: This study demonstrated the safety and feasibility of early hospital discharge for low-risk STEMI patients following successful primary PCI. The structured, multidisciplinary virtual follow-up schedule supported pathway helped achieve a favorable outcome with low cardiovascular mortality and MACE rates compared to a control group of patients who stayed in the hospital for >48 hours.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Neng Dai, Wenliang Che, Lu Liu, Wen Zhang, Guoqing Yin, Bin Xu, Yawei Xu, Shaofeng Duan, Haojun Yu, Chenguang Li, Kang Yao, Dong Huang, Junbo Ge
Summary: The Angio-IMR shows moderate correlation with HMR and high accuracy in predicting microcirculatory dysfunction. Angio-IMR measured after PCI can predict the risk of cardiac death or readmission due to heart failure in patients with CAD.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Multidisciplinary Sciences
Marjorie Canu, Charles Khouri, Stephanie Marliere, Estelle Vautrin, Nicolas Piliero, Olivier Ormezzano, Bernard Bertrand, Helene Bouvaist, Laurent Riou, Loic Djaileb, Clemence Charlon, Gerald Vanzetto, Matthieu Roustit, Gilles Barone-Rochette
Summary: Coronary microvascular dysfunction is common and associated with poor outcomes in STEMI patients. A systematic review and meta-analysis showed a significant association between IMR or HMR and long-term major adverse cardiovascular events in these patients.
Article
Cardiac & Cardiovascular Systems
Jordan B. Strom, Jiaman Xu, Ariela R. Orkaby, Changyu Shen, Brian R. Charest, Dae H. Kim, David J. Cohen, Daniel B. Kramer, John A. Spertus, Robert E. Gerszten, Robert W. Yeh
Summary: By linking adults aged >= 65 years in the US CoreValve Studies with Medicare inpatient claims, researchers found that a claims-based frailty index validated on the Fried index can accurately identify individuals with impairments in frailty, disability, cognitive dysfunction, and nutrition. Higher levels of frailty were associated with increased risk of adverse outcomes such as death, hospitalization, bleeding, and major adverse cardiovascular and cerebrovascular events.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Johannes B. Dahm
Summary: Although it is common practice in many places to treat STEMI patients with unfractionated heparin (UFH) in the ambulance or before coronary intervention, there are no recent data on the efficacy and safety of UFH administration before coronary intervention in the era of multiple platelet inhibitors and anticoagulants.
AKTUELLE KARDIOLOGIE
(2023)
Article
Cardiac & Cardiovascular Systems
David Meier, Mariama Akodad, Uri Landes, Aaron M. Barlow, Andrew G. Chatfield, Althea Lai, Georgios Tzimas, Gilbert H. L. Tang, Thomas Puehler, Georg Lutter, Jonathon A. Leipsic, Lars Sondergaard, David A. Wood, John G. Webb, Stephanie L. Sellers, Janarthanan Sathananthan
Summary: This study evaluated the impact of different transcatheter heart valve designs, neoskirt height, implant technique, and cell misalignment on coronary access after redo transcatheter aortic valve replacement.
JACC-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Medicine, General & Internal
Reut Schvartz, Lior Lupu, Shir Frydman, Shmuel Banai, Yacov Shacham, Amir Gal-Oz
Summary: This study investigated the relationship between AKI and mortality in STEMI patients after PCI, and found that AKI is a significant risk factor for mortality while higher BMI has a protective effect on survival.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Won-Keun Kim, Costanza Pellegrini, Sebastian Ludwig, Helge Moellmann, Florian Leuschner, Raj Makkar, Juergen Leick, Ignacio J. Amat-Santos, Oliver Doerr, Philipp Breitbart, Victor A. Jimenez Diaz, Maciej Dabrowski, Tanja Rudolph, Pablo Avanzas, Jatinderjit Kaur, Stefan Toggweiler, Sebastian Kerber, Patrick Ranosch, Damiano Regazzoli, Derk Frank, Uri Landes, John Webb, Marco Barbanti, Paola Purita, Thomas Pilgrim, Branislav Liska, Noriaki Tabata, Tobias Rheude, Moritz Seiffert, Clemens Eckel, Abdelhakim Allali, Roberto Valvo, Sung-Han Yoon, Nikos Werner, Holger Nef, Yeong-Hoon Choi, Christian W. Hamm, Jan-Malte Sinning
Summary: This study aimed to evaluate the feasibility of CA and PCI in acute settings among patients who have undergone TAVR. The study found that CA or PCI after TAVR in acute settings is usually successful, but selective coronary engagement may be more challenging in the presence of long SFPs. Among patients requiring PCI, prior diabetes, cardiogenic shock, and failed PCI were predictors of early mortality.
JACC-CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Cardiac & Cardiovascular Systems
Xida Li, Shuo Sun, Demou Luo, Xing Yang, Jingguang Ye, Shenghui Xu, Boyu Sun, Youti Zhang, Jianfang Luo, Yingling Zhou, Shengxian Tu, Haojian Dong
Summary: This study aimed to determine the optimal stent expansion strategy in primary percutaneous coronary intervention (pPCI) using novel angiography-based approaches. The results showed that stent expansion did not affect the final quantitative flow ratio (QFR) and microcirculatory resistance (MR), but it reduced flow speed in ST-elevation myocardial infarction (STEMI) patients. Mild underexpansion of 70%-80% did not seem to be associated with short-term prognosis, while overexpansion and underexpansion of <70% should be avoided due to the increased risk of major adverse cardiac events (MACEs) and no-reflow events.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Engineering, Biomedical
David Posawatz, Joshua Bloom, Alison Massed, Abhishek Chatterjee, Charles Resor, Yong Zhan, Andrew Weintraub, Masashi Kawabori
Summary: TAVR has become the preferred treatment for severe aortic stenosis, but there is a lack of cost-utility comparison between TAVR valves. This study compared the Sapien 3 and CoreValve Evolut R valves using cost-utility analysis and found that although S3 was more expensive, it was more effective and therefore the more cost-effective option.
Article
Multidisciplinary Sciences
Dominika Domokos, Andras Szabo, Gyongyver Banhegyi, Laszlo Major, Robert Gabor Kiss, David Becker, Istvan Ferenc Edes, Zoltan Ruzsa, Bela Merkely, Istvan Hizoh
Summary: The study suggests that the use of intravenous morphine may have no impact on long-term mortality and predischarge ejection fraction in ST-segment elevation myocardial infarction (STEMI) patients treated with primary PCI.
Article
Radiology, Nuclear Medicine & Medical Imaging
Mahmoud Mohamed, Maria Bosserdt, Viktoria Wieske, Benjamin Dubourg, Hatem Alkadhi, Mario J. Garcia, Sebastian Leschka, Elke Zimmermann, Abbas A. Shabestari, Bjarne L. Norgaard, Matthijs F. L. Meijs, Kristian A. Ovrehus, Axel C. P. Diederichsen, Juhani Knuuti, Bjrn A. Halvorsen, Vladymir Mendoza-Rodriguez, Yung-Liang Wan, Nuno Bettencourt, Eugenio Martuscelli, Ronny R. Buechel, Hans Mickley, Kai Sun, Simone Muraglia, Philipp A. Kaufmann, Bernhard A. Herzog, Jean-Claude Tardif, Georg M. Schuetz, Michael Laule, David E. Newby, Stephan Achenbach, Matthew Budoff, Robert Haase, Federico Biavati, Aldo Vasquez Mezquita, Peter Schlattmann, Marc Dewey
Summary: Combining coronary computed tomography angiography (CCTA) with coronary artery calcium (CAC) score can significantly improve the diagnosis of coronary artery disease (CAD). The addition of CAC score is particularly beneficial when CCTA alone is inconclusive.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zhongqin Zhou, Dongmei Wei, Shiganmo Azhe, Chuan Fu, Xiaoyue Zhou, Jing An, Davide Piccini, Jessica Bastiaansen, Yingkun Guo, Lingyi Wen
Summary: Self-navigated coronary MR angiography (SN-CMRA) can be used to evaluate coronary aneurysms (CAA) in patients with Kawasaki disease without increasing radiation. It has reliable diagnostic performance and application value, offering a simplified scanning procedure, shorter scan time, and comparable image quality and diagnostic accuracy compared to other imaging methods.
EUROPEAN RADIOLOGY
(2023)