Decitabine potentiates efficacy of doxorubicin in a preclinical trastuzumab-resistant HER2-positive breast cancer models

Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors

(2021) Neil T. Conlon et al.   BRITISH JOURNAL OF CANCER

Epigenetic Silencing of HER2 Expression during Epithelial-Mesenchymal Transition Leads to Trastuzumab Resistance in Breast Cancer

(2021) Babak Nami et al.   Life-Basel

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Decitabine Response in Breast Cancer Requires Efficient Drug Processing and Is Not Limited by Multidrug Resistance

(2020) Margaret L. Dahn et al.   MOLECULAR CANCER THERAPEUTICS

Decitabine- and 5-azacytidine resistance emerges from adaptive responses of the pyrimidine metabolism network

(2020) Xiaorong Gu et al.   LEUKEMIA

Evolving standards of care and new challenges in the management of HER2‐positive breast cancer

(2020) Grace M. Choong et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Abnormal Ferroptosis in Myelodysplastic Syndrome

(2020) Qi Lv et al.   Frontiers in Oncology

Epigenetics in Breast Cancer Therapy—New Strategies and Future Nanomedicine Perspectives

(2020) Verona Buocikova et al.   Cancers

Combining epigenetic drugs with other therapies for solid tumours — past lessons and future promise

(2019) Daphné Morel et al.   Nature Reviews Clinical Oncology

Effects of 5-Aza-2′-deoxycytidine (decitabine) on gene expression

(2018) Ratnam S. Seelan et al.   DRUG METABOLISM REVIEWS

Dual IRE1 RNase functions dictate glioblastoma development

(2018) Stéphanie Lhomond et al.   EMBO Molecular Medicine

DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine

(2018) Jia Yu et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigenetic therapy: azacytidine and decitabine in acute myeloid leukemia

(2018) Stephan R. Bohl et al.   Expert Review of Hematology

Recent Advances in the Treatment of Breast Cancer

(2018) Christy W. S. Tong et al.   Frontiers in Oncology

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources

(2018) Sebastian Köhler et al.   NUCLEIC ACIDS RESEARCH

Voltage-gated calcium channels: Novel targets for cancer therapy

(2017) Nam Nhut Phan et al.   Oncology Letters

Cytidine Deaminase Deficiency Reveals New Therapeutic Opportunities against Cancer

(2016) Hamza Mameri et al.   CLINICAL CANCER RESEARCH

In vitrogenotoxicity testing of four reference metal nanomaterials, titanium dioxide, zinc oxide, cerium oxide and silver: towards reliable hazard assessment

(2016) Naouale El Yamani et al.   MUTAGENESIS

A novel apoptosis-inducing mechanism of 5-aza-2′-deoxycitidine in melanoma cells: Demethylation of TNF-α and activation of FOXO1

(2015) Shunsuke Noguchi et al.   CANCER LETTERS

Combination therapy with epigenetic-targeted and chemotherapeutic drugs delivered by nanoparticles to enhance the chemotherapy response and overcome resistance by breast cancer stem cells

(2015) Shi-Yong Li et al.   JOURNAL OF CONTROLLED RELEASE

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

genomation: a toolkit to summarize, annotate and visualize genomic intervals

(2014) A. Akalin et al.   BIOINFORMATICS

Decitabine Induces Delayed Reactive Oxygen Species (ROS) Accumulation in Leukemia Cells and Induces the Expression of ROS Generating Enzymes

(2014) Tamer E. Fandy et al.   CLINICAL CANCER RESEARCH

Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin

(2013) Baoxu Pang et al.   Nature Communications

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Transient Low Doses of DNA-Demethylating Agents Exert Durable Antitumor Effects on Hematological and Epithelial Tumor Cells

(2012) Hsing-Chen Tsai et al.   CANCER CELL

Epithelial-to-mesenchymal transition (EMT) confers primary resistance to trastuzumab (Herceptin)

(2012) Cristina Oliveras-Ferraros et al.   CELL CYCLE

Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation

(2012) DONG YEOK SHIN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline-based chemotherapy and the demethylating agent decitabine

(2011) Ferda Ari et al.   CELL BIOCHEMISTRY AND FUNCTION

DNMT3B gene amplification predicts resistance to DNA demethylating drugs

(2011) Laia Simó-Riudalbas et al.   GENES CHROMOSOMES & CANCER

GOrevenge: A Novel Generic Reverse Engineering Method for the Identification of Critical Molecular Players, Through the Use of Ontologies

(2011) K. Moutselos et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Demethylating agent 5-aza-2-deoxycytidine enhances susceptibility of breast cancer cells to anticancer agents

(2010) Sameer Mirza et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The mammalian phenotype ontology: enabling robust annotation and comparative analysis

(2009) Cynthia L. Smith et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Anthracycline-trastuzumab regimens for HER2/neu-overexpressing breast cancer: current experience and future strategies

(2008) D. Rayson et al.   ANNALS OF ONCOLOGY

Antitumor Effects of Doxorubicin Followed by Zoledronic Acid in a Mouse Model of Breast Cancer

(2008) P. D. Ottewell et al.   JNCI-Journal of the National Cancer Institute