Review
Biochemistry & Molecular Biology
Leonardo Warzea Lima, Serenella Nardi, Veronica Santoro, Michela Schiavon
Summary: Selenium is an essential element for human metabolism, acting as antioxidants, protecting cells, and preventing metabolic disorders. It can enhance the catalytic activity of selenoproteins, strengthen antioxidant capacity, and help prevent viral infections. For SARS-CoV-2, selenium supplementation can serve as a complementary treatment.
Review
Biochemistry & Molecular Biology
Valentina N. Mal'tseva, Michael V. Goltyaev, Egor A. Turovsky, Elena G. Varlamova
Summary: This review presents the latest data on the role of selenium-containing agents in regulating diseases of the immune system, including defense mechanisms against viral infections. The article summarizes the contributions, mechanisms, and potential of different selenium compounds, selenoproteins, and selenium nanoparticles in immune process regulation, emphasizing their importance and key differences in mechanisms of action.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Ana Coelho Marques, Fernando C. Lidon, Ana Rita F. Coelho, Claudia Campos Pessoa, Diana Daccak, Ines Carmo Luis, Manuela Simoes, Paula Scotti-Campos, Ana Sofia Almeida, Mauro Guerra, Roberta G. Leitao, Ana Bagulho, Jose Moreira, Maria F. Pessoa, Paulo Legoinha, Jose C. Ramalho, Jose N. Semedo, Lourenco Palha, Catia Silva, Maria Manuela Silva, Karliana Oliveira, Isabel P. Pais, Fernando H. Reboredo
Summary: This study demonstrated that foliar application of selenium increased the selenium content in rice grains, and affected the levels of micro and macronutrients in the grains. The Ariete and Ceres varieties showed the highest enrichment of selenium.
Article
Agriculture, Multidisciplinary
Panfeng Liu, Lifang Song, Shuangnan Hao, Jie Qin, Chenbo Yang, Wude Yang, Meichen Feng, Meijun Zhang, Chao Wang, Xiaoyan Song
Summary: The study examined the effects of selenium application on the grain selenium content and yield of Tartary buckwheat. It was found that grain selenium content increased with higher selenium application concentration, while yield showed an initial increase followed by a decrease. The most effective biofortification programs varied based on factors such as variety, stage of application, and concentration of selenium.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Biotechnology & Applied Microbiology
Ali Mahmoud El-Badri, Ahmed M. Hashem, Maria Batool, Ahmed Sherif, Elsayed Nishawy, Mohammed Ayaad, Hamada M. Hassan, Ibrahim M. Elrewainy, Jing Wang, Jie Kuai, Bo Wang, Shixue Zheng, Guangsheng Zhou
Summary: BioSeNPs have positive effects on the growth and physiochemical attributes of rapeseed seedlings, enhancing seed germination, growth, and photosynthetic efficiency while reducing oxidative stress caused by salt stress. The nanoparticles regulate the activity of antioxidant enzymes and gene expression patterns to mitigate oxidative stress and cellular membrane damage. However, at high concentrations, bioSeNPs may have slight toxic effects.
JOURNAL OF NANOBIOTECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Lina He, Jiating Zhao, Liming Wang, Quancheng Liu, Yuqin Fan, Bai Li, Yong-Liang Yu, Chunying Chen, Yu-Feng Li
Summary: Selenium, an essential trace element, is known for its antioxidant and immunity-boosting capabilities, which can have a strong antiviral effect. NanoSelenium shows potential in combating COVID-19, highlighting the importance of Selenium in fighting various viruses.
Article
Plant Sciences
Shuangnan Hao, Panfeng Liu, Jie Qin, Lifang Song, Wude Yang, Meichen Feng, Meijun Zhang, Chao Wang, Xiaoyan Song
Summary: The effects of various factors on the selenium-enriched ability and yield of different oat varieties were comprehensively studied, showing that the selenium application dose, stage, and method had an impact on the grain selenium content and yield of oat.
Article
Food Science & Technology
Xiaolan Quan, Yuwei Cheng, Zhengfei Yang, Jia Yang, Weiming Fang, Yongqi Yin
Summary: This study investigated the mechanisms of isothiocyanate and selenium accumulation in broccoli sprouts under exogenous sodium selenite treatment. The results showed that the growth of broccoli sprouts was inhibited and the contents of total phenol and malondialdehyde were increased in 6-day-old sprouts under exogenous selenium treatment. The expression of genes regulating isothiocyanate and sulforaphane biosynthesis was up-regulated, while genes regulating selenium metabolism were significantly up-regulated. Furthermore, the proteomic analysis revealed different abundance of proteins related to metabolic pathways and biosynthetic pathways of secondary metabolites in 4-day-old broccoli sprouts under selenium treatment.
Article
Biochemistry & Molecular Biology
E. E. Uresti-Rivera, G. Mendez-Frausto, M. N. Medina-Rosales, J. Ventura-Juarez, M. H. Garcia-Hernandez
Summary: This study evaluated the modulation of regulatory T cell differentiation by sodium selenite. The results showed that sodium selenite reversibly affects T cell differentiation, increases immune response, and regulates the expression of suppressor molecules.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Wenxian Wang, Yufei Zhou, Dan Yang, Xianfen Zhang, Lijiao Guan, Yuding Zhang, Saipeng Huang
Summary: This study developed novel carbon quantum dots that can detect and quantify selenite, with good water solubility and biocompatibility, and imaging capabilities in cells. Therefore, these carbon quantum dots have great potential for detecting and treating selenite-associated diseases.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Public, Environmental & Occupational Health
Sharika Nuzhat, S. M. Tafsir Hasan, Parag Palit, Farzana Afroze, Rukaeya Amin, Md Ashraful Alam, Baharul Alam, Mohammod J. Chisti, Tahmeed Ahmed
Summary: During the COVID-19 pandemic, hospital admissions of children showed significant fluctuations, with children admitted during the pandemic more likely to suffer from severe illness and poor nutrition. Efforts are needed to mitigate the adverse effects of the pandemic on children's health.
BULLETIN OF THE WORLD HEALTH ORGANIZATION
(2022)
Article
Environmental Sciences
Jing Ge, Kai Guo, Cong Zhang, Milton Talukder, Mei-Wei Lv, Jin-Yang Li, Jin-Long Li
Summary: This study aimed to compare the superior antagonistic effects of Nano-Se, SeY, and SSe on Cd-induced inflammation response through the NF-kB/I kappa B pathway in the heart. Results demonstrated that Nano-Se was more effective in reversing Cd-induced histopathological changes and iNOS activities, reducing Cd accumulation, and antagonizing Cd-triggered inflammation response in chicken hearts compared to SeY and SSe. Se applications, especially Nano-Se, can be most efficiently used for relieving cardiotoxicity induced by Cd exposure.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Biochemistry & Molecular Biology
Junying Xiao, Na Li, Shengze Xiao, Yuzhou Wu, Hongmei Liu
Summary: This study demonstrated that chitosan-stabilized selenium nanoparticles (CS-SeNPs) and Na2SeO3 have significant anti-atherosclerotic activity in a high-fat-diet-fed mouse model of atherosclerosis. They were found to alleviate vascular endothelial dysfunction and inflammation, leading to reduced atherosclerotic lesions in mouse aortae. Importantly, CS-SeNPs showed potential for atherosclerosis prevention with lower toxicity compared to Na2SeO3. These findings suggest that selenium supplementation may be a promising therapeutic strategy for atherosclerosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Plant Sciences
Yan Li, Yiran Xiao, Jinghong Hao, Shuangxi Fan, Ruifang Dong, Haihong Zeng, Chaojie Liu, Yingyan Han
Summary: This paper investigated the selenium accumulation ability of lettuce and the effects of selenate and selenite on its growth and amino acid content. The results showed that lettuce could effectively convert inorganic selenium into organic selenium, and the addition of selenium improved photosynthesis and growth. The optimal selenium application was found to be 2 mu mol L-1, with some regions able to use 4 mu mol L-1 selenite. However, excessive selenium areas are not recommended for growing selenium-rich foods. Overall, lettuce has strong biofortification potential.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Olof Breuer, Ola Brodin, Ali Razaghi, David Brodin, Bente Gammelgaard, Mikael Bjoernstedt
Summary: The study analyzed the selenium species in plasma samples from cancer patients participating in a clinical trial and found that selenite, selenosugars, and unidentified peaks were detected. The identification of selenite even long after administration was unexpected and demonstrates its potential as a chemotherapeutic agent.
Review
Biotechnology & Applied Microbiology
Kamil Piwowarek, Edyta Lipinska, Marek Kieliszek
Summary: Every year, the industry generates large amounts of residues worldwide. These residues are often disposed of through methods such as landfills, incineration, or discharge into sewage, which are not ideal. This article discusses the latest achievements in biotechnology regarding bacterial reprocessing of residues to obtain valuable metabolites. The focus is on four metabolites - bacterial cellulose, propionic acid, vitamin B12, and PHAs. Considering global trends, there will likely be a significant increase in demand for these compounds in the near future. Cheap methods for their production need to be developed for profitability and commercialization. The article also covers factors affecting production, metabolic pathways, and potential and current applications, providing a comprehensive overview useful for academia, scientific communities, and industries.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Nuzhat Ahsan, Mohammad Imran, Yousuf Mohammed, Fatme Al Anouti, Mohammad Idreesh Khan, Tanushree Banerjee, Mohd Adnan, Fauzia Ashfaq, Marek Kieliszek, Syed Amir Ashraf, Afrozul Haq
Summary: The pathophysiology of COVID-19 involves inflammation, weakened immunity, immune cell infiltration, necrosis, lung hyperplasia, severe pneumonia, and potential mortality due to septic shock and organ failure. Vitamin D, zinc, and magnesium have been reported to improve the immune system against respiratory illnesses. This comprehensive review focuses on the mechanistic details of these micronutrients as immunomodulators and their potential role in preventing and treating respiratory illnesses.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Food Science & Technology
A. Shenbagam, Nishant Kumar, Kumar Rahul, Ashutosh Upadhyay, Malgorzata Gniewosz, Marek Kieliszek
Summary: This study investigated the effects of orange peel essential oils on the properties of aloe vera gel-based edible coating. The effects of the coating (with or without incorporation of orange peel essential oil) on the shelf life and characteristics of button mushrooms during storage were also studied. The results showed that the 50% concentration of aloe vera gel-based coating without essential oil had superior properties and could maintain the quality of mushrooms throughout storage. The highest concentration of orange peel essential oil significantly improved the postharvest quality of mushrooms and extended their shelf life.
FOOD AND BIOPROCESS TECHNOLOGY
(2023)
Article
Food Science & Technology
Brera Ghulam Nabi, Kinza Mukhtar, Waqar Ahmed, Muhammad Faisal Manzoor, Muhammad Modassar Ali Nawaz Ranjha, Marek Kieliszek, Zuhaib F. Bhat, Rana Muhammad Aadil
Summary: Natural pigments are widely used in food to provide color and improve taste. They are important in the food industry due to their nutritional and functional attributes. Consumers are increasingly interested in natural pigments as they are considered safer than artificial pigments. Some permitted natural pigments include betalains, flavonoids, carotenoids, and chlorophylls. However, there are restrictions on their use based on the source, quantity, and nature of the product. This review highlights the applications and advantages of permitted pigments in various food models.
Review
Food Science & Technology
Marek Kieliszek, Kamil Piwowarek, Anna M. Kot, Marta Wojtczuk, Marek Roszko, Marcin Bryla, Anka Trajkovska Petkoska
Summary: Nowadays, natural foods that can provide positive health effects are popular. Bees and their products are natural heritage that should be developed. This article presents the characteristics and uses of bee products in industry, highlighting their nutritional value and therapeutic properties. The research and opinions confirm the beneficial effect of bee products on health. Increasing consumer awareness of the positive impact of such food has led to a growing interest and demand, and new technologies have improved the process of obtaining bee products. Their use plays a significant role in various industries and promotes proper eating habits.
FOOD SCIENCE & NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Anna M. Kot, Wioletta Sek, Marek Kieliszek, Stanislaw Blazejak, Katarzyna Pobiega, Rita Brzezinska
Summary: This study tested 114 red yeast strains for their ability to synthesize carotenoids, and found that most strains produced torulene in high amounts. 48 strains with high total carotenoid content and torularhodin content were identified, belonging to 6 different genera.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Review
Microbiology
Wioletta Sek, Anna M. Kot, Alexander Rapoport, Marek Kieliszek
Summary: Anhydrobiosis is a state in which the metabolism of living organisms is temporarily delayed or suspended due to dehydration. The viability of yeast cells during the drying process depends on rehydration. Various cellular structures and compounds, such as the cell wall, vacuoles, mitochondria, trehalose, and lipid droplets, play important roles in anhydrobiosis. Additionally, specific proteins and genes are responsible for this process.
ARCHIVES OF MICROBIOLOGY
(2023)
Review
Medicine, Research & Experimental
Sameen Zafar, Muhammad Armaghan, Khushbukhat Khan, Nazia Hassan, Javad Sharifi-Rad, Solomon Habtemariam, Marek Kieliszek, Monica Butnariu, Iulia-Cristina Bagiu, Radu Vasile Bagiu, William C. Cho
Summary: Maytansine is an active drug derived from medicinal plants and microorganisms. Its pharmacological activities primarily include anticancer and antibacterial effects. The anticancer mechanism of maytansine is achieved through interaction with tubulin, inhibiting microtubule assembly and leading to cell cycle arrest and apoptosis. However, its non-selective cytotoxicity limits its clinical applications. Researchers have developed derivatives of maytansine with improved pharmacological activities. This review provides valuable insights into maytansine and its synthetic derivatives as anticancer agents.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Medicine, Research & Experimental
Muhammad Torequl Islam, Chandan Sarkar, Rajib Hossain, Md. Shimul Bhuia, Ileana Mardare, Marzhan Kulbayeva, Alibek Ydyrys, Daniela Calina, Solomon Habtemariam, Marek Kieliszek, Javad Sharifi-Rad, William C. Cho
Summary: Rheumatic diseases and disorders (RDDs) are chronic autoimmune diseases caused by genetic and environmental factors. Redox imbalance is found to be a serious consequence of RDDs, and an in-depth understanding of this imbalance is crucial for therapeutic strategies. Studies also suggest that peroxiredoxins and changes in lifestyle and diet may provide potential avenues for intervention.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Food Science & Technology
Syed Amir Ashraf, Danish Mahmood, Abd Elmoneim O. Elkhalifa, Arif Jamal Siddiqui, Mohammad Idreesh Khan, Fauzia Ashfaq, Mitesh Patel, Mejdi Snoussi, Marek Kieliszek, Mohd Adnan
Summary: This review discusses the issue of pesticide contamination in honey and its impact on human health. It highlights the consequences of uncontrolled pesticide use in agriculture and apiculture and calls for stricter regulation and monitoring.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Marek Kieliszek, Sayra N. Serrano Sandoval
Summary: Selenium is a crucial element for the proper functioning of human and animal organisms, and its content in food varies depending on the region and soil conditions. Proper diet selection is the main source of selenium supplementation, especially in areas with selenium deficiency. Insufficient selenium intake can lead to negative health effects and potentially life-threatening diseases. Therefore, it is important to develop methods for supplementing selenium in regions with low selenium content.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2023)
Article
Food Science & Technology
Nishant Kumar, Jaishankar Pratibha, Jaishankar Prasad, Ajay Yadav, Ashutosh Upadhyay, Anka Trajkovska Neeraj, Shruti Shukla, Anka Trajkovska Petkoska, Marek Heena, Shweta Suri, Malgorzata Gniewosz, Marek Kieliszek
Summary: Edible packaging plays a crucial role in protecting food from damage and improving its properties. This review discusses recent advances and trends in composite edible packaging, employing active agents such as plant extracts and nanomaterials. Development methods and challenges related to developing edible coatings and films are also addressed.
FOOD ENGINEERING REVIEWS
(2023)
Review
Biology
Paulina Smaruj, Marek Kieliszek
Summary: Many archaeal and bacterial organisms have a type of adaptive immune system called CRISPR-Cas, which recognizes and degrades foreign DNA similar to repeats in the CRISPR array. Cas1 genes, known as cas1-solo, have been identified using computational techniques. These genes are often found near PolB-like polymerase genes and are considered a new superfamily of mobile genetic elements called casposons.
Review
Endocrinology & Metabolism
Allah Rakha, Zunaira Ramzan, Nehal Umar, Hina Rasheed, Aneela Fatima, Zahoor Ahmed, Marek Kieliszek, Rana Muhammad Aadil
Summary: Metabolic syndrome is a multifactorial disorder that increases the risk of cardiovascular diseases and type-2 diabetes. Traditional drugs often have undesirable side effects, leading to a growing interest in herbal remedies like Withania somnifera. This plant has been found to have various health-promoting properties and plays a significant role in managing MetS.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2023)
