期刊
BIOINFORMATICS
卷 38, 期 12, 页码 3304-3305出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btac317
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资金
- National Science Foundation [DBI-1832184]
- US Department of Energy [DE-SC0019749]
- National Cancer Institute, National Institute of Allergy and Infectious Diseases
- National Institute of General Medical Sciences of the National Institutes of Health [R01GM133198]
This article presents a new library that allows for customizable interactive views between the positional features of protein and nucleic acid sequences and their 3D structures, providing researchers with a better understanding of the mechanisms underlying the functions of biological macromolecules at the atomic level.
Motivation: Mapping positional features from one-dimensional (1D) sequences onto three-dimensional (3D) structures of biological macromolecules is a powerful tool to show geometric patterns of biochemical annotations and provide a better understanding of the mechanisms underpinning protein and nucleic acid function at the atomic level. Results: We present a new library designed to display fully customizable interactive views between 1D positional features of protein and/or nucleic acid sequences and their 3D structures as isolated chains or components of macromolecular assemblies.
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