Wireless USB-like electrochemical platform for individual electrochemical sensing in microdroplets

The portable electrochemical platform can adapt to more usage scenarios, which is essential for drug discovery, toxicology, and cell biology. Here, we constructed the wireless USB-like electrochemical platform for simultaneous multi-channel electrochemical sensing in microdroplet array. On such platform, multi-channel mini-pillar arrays can anchor reagent droplet (a few microliters to dozens of microliters), and the wireless USB-like electrochemical platform can achieve simultaneously multi-channel detection. As a concept-of-proof for multi- channel, the 4*4 channels are chosen as a model to proof the practicality of such portable electrochemical platform, the relative standard deviation (RSD) of such a platform in microdroplets sensing is below 5% level. The quantitative electrochemical analysis of multiple glucose concentrations in miniature workstation was also achieved, and only 0.97% difference between traditional electrochemical workstation. The wireless USB-like electrochemical platform with the characteristics of cloud data management and multi-channel, which enables remote detection and analysis and presents an opportunity for future portable high-throughput biomedical applications. (C) 2022 Elsevier B.V. All rights reserved.

Automated summary

The study presents a portable electrochemical platform for multi-channel sensing and analysis in microdroplet arrays. The platform demonstrates high accuracy and practicality, making it suitable for drug discovery and cell biology research. It also features cloud data management and remote analysis capabilities.