Fetal hemoglobin in β hemoglobinopathies: Is enough too much?

Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial

(2022) Elisa Magrin et al.   NATURE MEDICINE

Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, phase 3 trial

(2021) Jo Howard et al.   Lancet Haematology

Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin

(2021) Eric R Henry et al.   BLOOD

High‐oxygen‐affinity hemoglobinopathy‐associated erythrocytosis: Clinical outcomes and impact of therapy in 41 cases

(2021) Naseema Gangat et al.   AMERICAN JOURNAL OF HEMATOLOGY

Biologic and Clinical Efficacy of LentiGlobin for Sickle Cell Disease

(2021) Julie Kanter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of an allosteric hemoglobin affinity modulator on arterial blood gases and cardiopulmonary responses during normoxic and hypoxic low-intensity exercise

(2020) Glenn M. Stewart et al.   JOURNAL OF APPLIED PHYSIOLOGY

Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease

(2020) Erica B. Esrick et al.   NEW ENGLAND JOURNAL OF MEDICINE

CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia

(2020) Haydar Frangoul et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacokinetics and Pharmacodynamics of Voxelotor (GBT440) in Healthy Adults and Patients With Sickle Cell Disease

(2019) Athiwat Hutchaleelaha et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease

(2019) Elliott Vichinsky et al.   NEW ENGLAND JOURNAL OF MEDICINE

HOMOZYGOUS DELETION ALFA-THALASSEMIA AND HEREDITARY PERSISTENCE OF FETAL HEMOGLOBIN, TWO GENETIC FACTORS PREDICTIVE THE REDUCTION OF MORBIDITY AND MORTALITY DURING PREGNANCY IN SICKLE CELL PATIENTS . A REPORT FROM DEMOCRATIC REPUBLIC OF CONGO

(2019) Tite Minga MIKOBI et al.   Mediterranean Journal of Hematology and Infectious Diseases

Wake-up Sleepy Gene: Reactivating Fetal Globin for β-Hemoglobinopathies

(2018) Beeke Wienert et al.   TRENDS IN GENETICS

Fetal haemoglobin levels and haematological characteristics of compound heterozygotes for haemoglobin S and deletional hereditary persistence of fetal haemoglobin

(2011) Duyen A. Ngo et al.   BRITISH JOURNAL OF HAEMATOLOGY

Pregnancy outcomes in women with elevated levels of fetal hemoglobin

(2011) Ally Murji et al.   Journal of Maternal-Fetal & Neonatal Medicine