期刊
ACTA PAEDIATRICA
卷 111, 期 7, 页码 1427-1434出版社
WILEY
DOI: 10.1111/apa.16346
关键词
bioelectrical impedance analysis; dual-energy X-ray absorptiometry; fat mass; fat-free mass; maternal obesity; offspring body composition
类别
资金
- Aase and Ejner Danielsens Foundation
- Augustinus Foundation - University of Copenhagen Excellence Program for Interdisciplinary Research
The study found that birthweight z-score (BWZ) was positively associated with fat-free mass (FFM), height, fat-free mass index (FFMI), fat mass (FM), and fat mass index (FMI) at 3 years of age. Additionally, newborn fat-free mass (FFM) was positively associated with FFM, height, FFMI, and FM at 3 years, while newborn fat mass (FM) showed positive trends with FM and FMI at 3 years of age.
Aim We investigated associations between newborn body composition and anthropometry and body composition at 3 years in Danish children born from obese mothers. Methods Analyses are based on data from the observational cohort study SKOT II (SKOT; small children's diet and well-being (Danish)). Body composition at birth and at 3 years was assessed by dual-energy X-ray absorptiometry (DXA) scans and bioelectrical impedance analysis (BIA), respectively. Multiple linear regression models were applied to determine associations between newborn body composition and anthropometry and body composition at 3 years. Results Birthweight z-score (BWZ) was positively associated with fat-free mass (FFM), height, fat-free mass index (FFMI), fat mass (FM) and fat mass index (FMI) at 3 years. Newborn FFM was positively associated with FFM, height, FFMI and FM at 3 years, and positive trends were seen between newborn FM and FM and FMI at 3 years. Conclusion We showed that infants born with a higher BWZ go on to be taller at 3 years. They also grow to be heavier, to which FM and FFM both contribute, independently of linear growth. Additionally, it seems that FFM tracks into early childhood, thus supporting intrauterine programming of later health.
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