Reactive Oxygen Species─Responsive Lipid Nanoparticles for Effective RNAi and Corneal Neovascularization Therapy

Delivery of mRNA vaccine with a lipid-like material potentiates antitumor efficacy through Toll-like receptor 4 signaling

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In vivo effect of bevacizumab-loaded albumin nanoparticles in the treatment of corneal neovascularization

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Arginine-based poly(ester amide) nanoparticle platform: From structure–property relationship to nucleic acid delivery

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Combination antitumor immunotherapy with VEGF and PIGF siRNA via systemic delivery of multi-functionalized nanoparticles to tumor-associated macrophages and breast cancer cells

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Redox-Responsive Nanoparticle-Mediated Systemic RNAi for Effective Cancer Therapy

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The long-term effect of tacrolimus on alkali burn-induced corneal neovascularization and inflammation surpasses that of anti-vascular endothelial growth factor

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Gαi1 and Gαi3mediate VEGF-induced VEGFR2 endocytosis, signaling and angiogenesis

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ROS-sensitive thioketal-linked polyphosphoester-doxorubicin conjugate for precise phototriggered locoregional chemotherapy

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Reactive oxygen species activated nanoparticles with tumor acidity internalization for precise anticancer therapy

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Fibroblast growth factor-2 drives and maintains progressive corneal neovascularization following HSV-1 infection

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Reactive oxygen species (ROS)-responsive nanomedicine for RNAi-based cancer therapy

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Assessment of therapeutic options for reducing alkali burn-induced corneal neovascularization and inflammation

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Inhibition of VEGF mediated corneal neovascularization by anti-angiogenic peptide nanofibers

(2016) Berna Senturk et al.   BIOMATERIALS

Nanoparticles responsive to the inflammatory microenvironment for targeted treatment of arterial restenosis

(2016) Shibin Feng et al.   BIOMATERIALS

Fluorescent boronate-based polymer nanoparticles with reactive oxygen species (ROS)-triggered cargo release for drug-delivery applications

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In vitro and ex vivo strategies for intracellular delivery

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Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles

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Bioresponsive materials

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Real-Time Monitoring of ATP-Responsive Drug Release Using Mesoporous-Silica-Coated Multicolor Upconversion Nanoparticles

(2015) Jinping Lai et al.   ACS Nano

Reactive oxygen species and glutathione dual redox-responsive micelles for selective cytotoxicity of cancer

(2015) Yi-Ting Chiang et al.   BIOMATERIALS

Oxidative Stress to the Cornea, Changes in Corneal Optical Properties, and Advances in Treatment of Corneal Oxidative Injuries

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CD31 signals confer immune privilege to the vascular endothelium

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Combinatorially Designed Lipid-like Nanoparticles for Intracellular Delivery of Cytotoxic Protein for Cancer Therapy

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Dual Inhibition of PI3K-AKT-mTOR- and RAF-MEK-ERK-signaling is synergistic in cholangiocarcinoma and reverses acquired resistance to MEK-inhibitors

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A nairovirus isolated from African bats causes haemorrhagic gastroenteritis and severe hepatic disease in mice

(2014) Akihiro Ishii et al.   Nature Communications

Suppression of alkali-induced oxidative injury in the cornea by mesenchymal stem cells growing on nanofiber scaffolds and transferred onto the damaged corneal surface

(2013) Jitka Cejkova et al.   EXPERIMENTAL EYE RESEARCH

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

Dye/Peroxalate Aggregated Nanoparticles with Enhanced and Tunable Chemiluminescence for Biomedical Imaging of Hydrogen Peroxide

(2012) Yong-Deok Lee et al.   ACS Nano

Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species

(2012) Peter Kovacic et al.   Current Neuropharmacology

Glycopolypeptides with a Redox-Triggered Helix-to-Coil Transition

(2012) Jessica R. Kramer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Corneal Neovascularization: An Anti-VEGF Therapy Review

(2012) Jin-Hong Chang et al.   SURVEY OF OPHTHALMOLOGY

A Combinatorial Library of Unsaturated Lipidoids for Efficient Intracellular Gene Delivery

(2012) Ming Wang et al.   ACS Synthetic Biology

Reactive oxygen species in cardiovascular disease

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Engineering Nanocarriers for siRNA Delivery

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Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

(2010) D. Scott Wilson et al.   NATURE MATERIALS

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

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Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease

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