Roles of RNA-Binding Proteins in DNA Damage Response

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles

(2015) Sven Hennig et al.   JOURNAL OF CELL BIOLOGY

Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)

(2015) Matthias Altmeyer et al.   Nature Communications

RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation

(2015) Ming Yuan et al.   Oncotarget

The PSO4 Protein Complex Associates with Replication Protein A (RPA) and Modulates the Activation of Ataxia Telangiectasia-mutated and Rad3-related (ATR)

(2014) Li Wan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

(2014) Kienan I. Savage et al.   MOLECULAR CELL

DNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal

(2014) Sébastien Britton et al.   NUCLEIC ACIDS RESEARCH

The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage

(2013) Adam S. Mastrocola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

(2013) Tetsuro Hirose et al.   MOLECULAR BIOLOGY OF THE CELL

PRP19 Transforms into a Sensor of RPA-ssDNA after DNA Damage and Drives ATR Activation via a Ubiquitin-Mediated Circuitry

(2013) Alexandre Maréchal et al.   MOLECULAR CELL

Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons

(2013) Wen-Yuan Wang et al.   NATURE NEUROSCIENCE

Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition

(2013) Matteo Berti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage

(2013) Stuart L. Rulten et al.   NUCLEIC ACIDS RESEARCH

The Role of hnRPUL1 Involved in DNA Damage Response Is Related to PARP1

(2013) Zehui Hong et al.   PLoS One

The role of ADP-ribosylation in regulating DNA double-strand break repair

(2012) Catherine J. Pears et al.   CELL CYCLE

Nuclear factor κB predicts poor outcome in patients with hormone-naive prostate cancer with high nuclear androgen receptor

(2012) Lewis MacKenzie et al.   HUMAN PATHOLOGY

Regulation of DNA-End Resection by hnRNPU-like Proteins Promotes DNA Double-Strand Break Signaling and Repair

(2012) Sophie E. Polo et al.   MOLECULAR CELL

A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response

(2012) Britt Adamson et al.   NATURE CELL BIOLOGY

PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks

(2012) Jana Krietsch et al.   NUCLEIC ACIDS RESEARCH

Visualization of a DNA-PK/PARP1 complex

(2012) Laura Spagnolo et al.   NUCLEIC ACIDS RESEARCH

Topoisomerase IIβ associates with Ku70 and PARP-1 during double strand break repair of DNA in neurons

(2011) Rajakumar Mandraju et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The Coactivator activator CoAA regulates PEA3 group member transcriptional activity

(2011) Kathye Verreman et al.   BIOCHEMICAL JOURNAL

ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes

(2011) K. Mazan-Mamczarz et al.   BLOOD

Competition between PARP-1 and Ku70 control the decision between high-fidelity and mutagenic DNA repair

(2011) M.N. Paddock et al.   DNA REPAIR

Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation

(2011) Kiyoshi Masuda et al.   EMBO JOURNAL

The Prp19 complex is a novel transcription elongation factor required for TREX occupancy at transcribed genes

(2011) S. Chanarat et al.   GENES & DEVELOPMENT

The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complex

(2011) C. J. David et al.   GENES & DEVELOPMENT

The Ewing Sarcoma Protein Regulates DNA Damage-Induced Alternative Splicing

(2011) Maria Paola Paronetto et al.   MOLECULAR CELL

A siRNA-Based Screen for Genes Involved in Chromosome End Protection

(2011) Daniel H. Lackner et al.   PLoS One

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome

(2010) E. J. Song et al.   GENES & DEVELOPMENT

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination

(2009) Helen E Bryant et al.   EMBO JOURNAL

Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint

(2009) Nianxiang Zhang et al.   EMBO REPORTS

Heterogeneous Nuclear Ribonucleoprotein G Regulates Splice Site Selection by Binding to CC(A/C)-rich Regions in Pre-mRNA

(2009) Bettina Heinrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Pre- mRNAtrans-Splicing of Coactivator CoAA and Corepressor RBM4 during Stem/Progenitor Cell Differentiation

(2009) Yang S. Brooks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability

(2009) Renee D. Paulsen et al.   MOLECULAR CELL

PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA

(2008) Kazuto Sugimura et al.   JOURNAL OF CELL BIOLOGY

Human Embryonic Stem Cell-Derived Dopaminergic Neurons Reverse Functional Deficit in Parkinsonian Rats

(2007) Dali Yang et al.   STEM CELLS