End-stage renal disease in a child with focal segmental glomerulosclerosis associated with a homozygous NUP93 variant

This report highlights that the genetic causes of FSGS, including NUP93 gene variant, such as the one described in this report, progress to end-stage renal disease rapidly and that the risk of recurrence post-renal transplantation is less likely.

Automated summary

The report emphasizes that genetic causes of FSGS, including the NUP93 gene variant, can lead to rapid progression to end-stage renal disease, but the risk of recurrence post-renal transplantation is lower.