标题
Mitochondria-targeted drugs for diabetic kidney disease
作者
关键词
Diabetic kidney disease (DKD), Imeglimin, Metformin, Mitochondrial function, NFE-2 related factor 2 (Nrf2), Reactive oxygen species (ROS), Sodium-glucose cotransporter 2 (SGLT2)
出版物
Heliyon
Volume 8, Issue 2, Pages e08878
出版商
Elsevier BV
发表日期
2022-02-03
DOI
10.1016/j.heliyon.2022.e08878
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Imeglimin amplifies glucose-stimulated insulin release from diabetic islets via a distinct mechanism of action
- (2021) Sophie Hallakou-Bozec et al. PLoS One
- The IL-8-CXCR1/2 axis contributes to diabetic kidney disease
- (2021) Cristian Loretelli et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- AMPK agonist alleviate renal tubulointerstitial fibrosis via activating mitophagy in high fat and streptozotocin induced diabetic mice
- (2021) Ya-chun Han et al. Cell Death & Disease
- DPP‐4 inhibitor reduces striatal microglial deramification after sensorimotor cortex injury induced by external force impact
- (2020) Yu‐Wen Hung et al. FASEB JOURNAL
- Linagliptin affects IRS1/Akt signaling and prevents high glucose-induced apoptosis in podocytes
- (2020) Akira Mima et al. Scientific Reports
- Randomized Clinical Trial on the Effect of Bardoxolone Methyl on GFR in Diabetic Kidney Disease Patients (TSUBAKI Study)
- (2020) Masaomi Nangaku et al. Kidney International Reports
- Sitagliptin promotes mitochondrial biogenesis in human SH‐SY5Y cells by increasing the expression of PGC‐1α/NRF1/TFAM
- (2019) Guohu Weng et al. IUBMB LIFE
- Mitochondria, the NLRP3 Inflammasome, and Sirtuins in Type 2 Diabetes: New Therapeutic Targets
- (2018) Susana Rovira-Llopis et al. ANTIOXIDANTS & REDOX SIGNALING
- Metformin Targets Mitochondrial Glycerophosphate Dehydrogenase to Control Rate of Oxidative Phosphorylation and Growth of Thyroid CancerIn VitroandIn Vivo
- (2018) Shilpa Thakur et al. CLINICAL CANCER RESEARCH
- Bardoxolone—the Phoenix?
- (2018) Robert D. Toto JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo
- (2018) Anila K. Madiraju et al. NATURE MEDICINE
- Ipragliflozin improves mitochondrial abnormalities in renal tubules induced by a high-fat diet
- (2018) Susumu Takagi et al. Journal of Diabetes Investigation
- Obesity-associated glomerular inflammation increases albuminuria without renal histological changes
- (2018) Akira Mima et al. FEBS Open Bio
- Low metformin causes a more oxidized mitochondrial NADH/NAD redox state in hepatocytes and inhibits gluconeogenesis by a redox-independent mechanism
- (2018) Ahmed Alshawi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- High glucose repatterns human podocyte energy metabolism during differentiation and diabetic nephropathy
- (2017) Toshiyuki Imasawa et al. FASEB JOURNAL
- Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction
- (2017) Weier Qi et al. NATURE MEDICINE
- Mitochondrial energetics in the kidney
- (2017) Pallavi Bhargava et al. Nature Reviews Nephrology
- Carvedilol promotes mitochondrial biogenesis by regulating the PGC-1/TFAM pathway in human umbilical vein endothelial cells (HUVECs)
- (2016) Kai Yao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Role of Mitochondria in Diabetic Kidney Disease
- (2016) Stein Hallan et al. Current Diabetes Reports
- A Small Molecule That Protects the Integrity of the Electron Transfer Chain Blocks the Mitochondrial Apoptotic Pathway
- (2016) Xian Jiang et al. MOLECULAR CELL
- CTLA4-Ig in B7-1-positive diabetic and non-diabetic kidney disease
- (2015) Roberto Bassi et al. DIABETOLOGIA
- Imeglimin Normalizes Glucose Tolerance and Insulin Sensitivity and Improves Mitochondrial Function in Liver of a High-Fat, High-Sucrose Diet Mice Model
- (2015) Guillaume Vial et al. DIABETES
- The Efficacy and Safety of Imeglimin as Add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Sitagliptin Monotherapy
- (2014) Pascale Fouqueray et al. DIABETES CARE
- Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
- (2014) Anila K. Madiraju et al. NATURE
- Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides
- (2014) Kıvanç Birsoy et al. NATURE
- Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease
- (2013) Dick de Zeeuw et al. NEW ENGLAND JOURNAL OF MEDICINE
- Dipeptidyl Peptidase IV Inhibition Activates CREB and Improves Islet Vascularization through VEGF-A/VEGFR-2 Signaling Pathway
- (2013) Balaji Samikannu et al. PLoS One
- The high Nrf2 expression in human acute myeloid leukemia is driven by NF- B and underlies its chemo-resistance
- (2012) S. A. Rushworth et al. BLOOD
- Cellular Responses to the Metal-Binding Properties of Metformin
- (2012) L. Logie et al. DIABETES
- Protective Effects of GLP-1 on Glomerular Endothelium and Its Inhibition by PKC Activation in Diabetes
- (2012) A. Mima et al. DIABETES
- The Efficacy and Safety of Imeglimin as Add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Metformin Monotherapy
- (2012) P. Fouqueray et al. DIABETES CARE
- Imeglimin, a novel glimin oral antidiabetic, exhibits a good efficacy and safety profile in type 2 diabetic patients
- (2012) V. Pirags et al. DIABETES OBESITY & METABOLISM
- Glomerular VEGF resistance induced by PKCδ/SHP-1 activation and contribution to diabetic nephropathy
- (2012) Akira Mima et al. FASEB JOURNAL
- Nrf2–MafG heterodimers contribute globally to antioxidant and metabolic networks
- (2012) Yosuke Hirotsu et al. NUCLEIC ACIDS RESEARCH
- Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy
- (2011) Hongting Zheng et al. DIABETES
- Glomerular-specific protein kinase C-β-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity
- (2011) Akira Mima et al. KIDNEY INTERNATIONAL
- An Autopsy Case of Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS) with Intestinal Bleeding in Chronic Renal Failure
- (2011) Akira Mima et al. RENAL FAILURE
- Oxidative Stress and Diabetic Complications
- (2010) Ferdinando Giacco et al. CIRCULATION RESEARCH
- Aberrant cytokines/chemokines production correlate with proteinuria in patients with overt diabetic nephropathy
- (2010) Chia-Chao Wu et al. CLINICA CHIMICA ACTA
- Urinary Smad1 Is a Novel Marker to Predict Later Onset of Mesangial Matrix Expansion in Diabetic Nephropathy
- (2008) A. Mima et al. DIABETES
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