Diazoxide Post-conditioning Activates the HIF-1/HRE Pathway to Induce Myocardial Protection in Hypoxic/Reoxygenated Cardiomyocytes

Mechanism of the hypoxia inducible factor 1/hypoxic response element pathway in rat myocardial ischemia/diazoxide post‑conditioning

(2020) Jin Li et al.   Molecular Medicine Reports

LncRNA Fendrr inhibits hypoxia/reoxygenation‐induced cardiomyocyte apoptosis by downregulating p53 expression

(2020) Xiang Li et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The mitochondrial K-ATP channel opener diazoxide upregulates STIM1 and Orai1 via ROS and the MAPK pathway in adult rat cardiomyocytes

(2020) Joice T. Gavali et al.   Cell and Bioscience

Mitochondrial proteomics alterations in rat hearts following ischemia/reperfusion and diazoxide post‑conditioning

(2020) Yunchao Pan et al.   Molecular Medicine Reports

Identification of an ATP-sensitive potassium channel in mitochondria

(2019) Angela Paggio et al.   NATURE

Remote Ischemic Preconditioning and Diazoxide Protect from Hepatic Ischemic Reperfusion Injury by Inhibiting HMGB1-Induced TLR4/MyD88/NF-κB Signaling

(2019) Won Uk Koh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Good, the Bad, and the Ugly of ROS: New Insights on Aging and Aging-Related Diseases from Eukaryotic and Prokaryotic Model Organisms

(2018) Ana L. Santos et al.   Oxidative Medicine and Cellular Longevity

Inflammation following acute myocardial infarction: Multiple players, dynamic roles, and novel therapeutic opportunities

(2018) Sang-Bing Ong et al.   PHARMACOLOGY & THERAPEUTICS

The cardioprotective effects of secretory leukocyte protease inhibitor against myocardial ischemia/reperfusion injury

(2018) Eakkapote Prompunt et al.   Experimental and Therapeutic Medicine

Opening of mitoKATP improves cardiac function and inhibits apoptosis via the AKT-Foxo1 signaling pathway in diabetic cardiomyopathy

(2018) Peng Duan et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

PI3K/Akt and HIF‑1 signaling pathway in hypoxia‑ischemia (Review)

(2018) Zhen Zhang et al.   Molecular Medicine Reports

Mitochondrial depolarization stimulates vascular repair‐relevant functions of CD34 + cells via reactive oxygen species‐induced nitric oxide generation

(2018) Shrinidh Joshi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex III

(2017) Paavo Korge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ischemic Postconditioning Protects Against Intestinal Ischemia/Reperfusion Injury via the HIF-1α/miR-21 Axis

(2017) Zhongzhi Jia et al.   Scientific Reports

Targeting the ROS-HIF-1-endothelin axis as a therapeutic approach for the treatment of obstructive sleep apnea-related cardiovascular complications

(2016) Elise Belaidi et al.   PHARMACOLOGY & THERAPEUTICS

Protective approaches against myocardial ischemia reperfusion injury

(2016) Xianchi Li et al.   Experimental and Therapeutic Medicine

Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury

(2015) Giampaolo Morciano et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Long working hours and risk of coronary heart disease and stroke: a systematic review and meta-analysis of published and unpublished data for 603 838 individuals

(2015) Mika Kivimäki et al.   LANCET

Recent Advances in Developing Inhibitors for Hypoxia-Inducible Factor Prolyl Hydroxylases and Their Therapeutic Implications

(2015) So Kim et al.   MOLECULES

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1

(2014) Raquel Requejo-Aguilar et al.   Nature Communications

Cellular and molecular mechanisms in the hypoxic tissue: role of HIF-1 and ROS

(2013) Andrea B. Zepeda et al.   CELL BIOCHEMISTRY AND FUNCTION

Pharmacologic Therapy That Simulates Conditioning for Cardiac Ischemic/Reperfusion Injury

(2013) Vivek Sivaraman et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Preconditioning with Associated Blocking of Ca2+ Inflow Alleviates Hypoxia-Induced Damage to Pancreatic β-Cells

(2013) Zuheng Ma et al.   PLoS One

Induction of inducible nitric oxide synthase by isoflurane post-conditioning via hypoxia inducible factor-1α during tolerance against ischemic neuronal injury

(2012) Qi Fang Li et al.   BRAIN RESEARCH

Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning

(2012) K. Sarkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of hypoxia-inducible factor 1 and the loss of the cellular response to hypoxia in diabetes

(2011) C. F. Bento et al.   DIABETOLOGIA

Mitochondrial reprogramming through cardiac oxygen sensors in ischaemic heart disease

(2010) Susana Cadenas et al.   CARDIOVASCULAR RESEARCH

Hypoxia-Inducible Factor-1 Is Central to Cardioprotection

(2008) Tobias Eckle et al.   CIRCULATION

Mitochondria and cellular oxygen sensing in the HIF pathway

(2007) Cormac T. Taylor   BIOCHEMICAL JOURNAL