Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease

Cellular senescence in the aging retina and developments of senotherapies for age-related macular degeneration

(2021) Keng Siang Lee et al.   Journal of Neuroinflammation

Involvement of regulated necrosis in blinding diseases: Focus on necroptosis and ferroptosis

(2020) Jing-Jie Peng et al.   EXPERIMENTAL EYE RESEARCH

Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model

(2019) Peisu Zhang et al.   NATURE NEUROSCIENCE

The neuropathological diagnosis of Alzheimer’s disease

(2019) Michael A. DeTure et al.   Molecular Neurodegeneration

Elovanoids counteract oligomeric β-amyloid-induced gene expression and protect photoreceptors

(2019) Khanh V. Do et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retinal thinning of inner sub-layers is associated with cortical atrophy in a mouse model of Alzheimer’s disease: a longitudinal multimodal in vivo study

(2019) Samuel Chiquita et al.   Alzheimers Research & Therapy

The retina as a window to early dysfunctions of Alzheimer's disease following studies with a 5xFAD mouse model

(2018) Chiara Criscuolo et al.   NEUROBIOLOGY OF AGING

Tau protein aggregation is associated with cellular senescence in the brain

(2018) Nicolas Musi et al.   AGING CELL

Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline

(2018) Tyler J. Bussian et al.   NATURE

Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice

(2017) Tuhina Prasad et al.   Scientific Reports

Retinal amyloid peptides and complement factor H in transgenic models of Alzheimerʼs disease

(2016) Peter N. Alexandrov et al.   NEUROREPORT

Melanopsin retinal ganglion cell loss in Alzheimer disease

(2015) Chiara La Morgia et al.   ANNALS OF NEUROLOGY

Prevention of sporadic Alzheimer's disease: lessons learned from clinical trials and future directions

(2015) Sandrine Andrieu et al.   LANCET NEUROLOGY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Higher-Order Architecture of Rhodopsin in Intact Photoreceptors and Its Implication for Phototransduction Kinetics

(2015) Monika Gunkel et al.   STRUCTURE

Synaptic remodeling of neuronal circuits in early retinal degeneration

(2015) Florentina Soto et al.   Frontiers in Cellular Neuroscience

Alzheimer’s Disease-Related Protein Expression in the Retina of Octodon degus

(2015) Lucia Y. Du et al.   PLoS One

Rip3 knockdown rescues photoreceptor cell death in blind pde6c zebrafish

(2014) I A Viringipurampeer et al.   CELL DEATH AND DIFFERENTIATION

Evaluation of the chorioretinal thickness changes in Alzheimer's disease using spectral-domain optical coherence tomography

(2014) Hasan Ali Bayhan et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Single App knock-in mouse models of Alzheimer's disease

(2014) Takashi Saito et al.   NATURE NEUROSCIENCE

Intracellular amyloid beta alters the tight junction of retinal pigment epithelium in 5XFAD mice

(2014) Sung Wook Park et al.   NEUROBIOLOGY OF AGING

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Receptor Interacting Protein Kinase-Mediated Necrosis Contributes to Cone and Rod Photoreceptor Degeneration in the Retina Lacking Interphotoreceptor Retinoid-Binding Protein

(2013) K. Sato et al.   JOURNAL OF NEUROSCIENCE

Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation

(2013) William A Eimer et al.   Molecular Neurodegeneration

Photoreceptor cell death and rescue in retinal detachment and degenerations

(2013) Yusuke Murakami et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Structural and Functional Impairment of the Retina and Optic Nerve in Alzheimer’s Disease

(2012) Marilita M Moschos et al.   Current Alzheimer Research

Neuroprotective Strategies for the Treatment of Inherited Photoreceptor Degeneration

(2012) D. Trifunovic et al.   CURRENT MOLECULAR MEDICINE

Alzheimer’s Disease in the Retina: Imaging Retinal Aß Plaques for Early Diagnosis and Therapy Assessment

(2012) Yosef Koronyo et al.   Neurodegenerative Diseases

Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration

(2012) Y. Murakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Clifford R. Jack et al.   Alzheimers & Dementia

Impact of cellular senescence signature on ageing research

(2010) Ewa Sikora et al.   AGEING RESEARCH REVIEWS

Pattern electroretinogram (PERG) and pattern visual evoked potential (PVEP) in the early stages of Alzheimer’s disease

(2010) Kamila Krasodomska et al.   DOCUMENTA OPHTHALMOLOGICA

Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait

(2010) Alan F. Wright et al.   NATURE REVIEWS GENETICS

Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease

(2010) Sadim Jawhar et al.   NEUROBIOLOGY OF AGING

Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

(2010) Maya Koronyo-Hamaoui et al.   NEUROIMAGE

Retinal nerve fiber layer structure abnormalities in early Alzheimer's disease: Evidence in optical coherence tomography

(2010) Yan Lu et al.   NEUROSCIENCE LETTERS

Viewing Ageing Eyes: Diverse Sites of Amyloid Beta Accumulation in the Ageing Mouse Retina and the Up-Regulation of Macrophages

(2010) Jaimie Hoh Kam et al.   PLoS One

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer’s disease

(2009) R. Michael Dutescu et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Functional remodeling of glutamate receptors by inner retinal neurons occurs from an early stage of retinal degeneration

(2009) Jacqueline Chua et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

Multimodal techniques for diagnosis and prognosis of Alzheimer's disease

(2009) Richard J. Perrin et al.   NATURE

Roles of STAT3/SOCS3 Pathway in Regulating the Visual Function and Ubiquitin-Proteasome-dependent Degradation of Rhodopsin during Retinal Inflammation

(2008) Yoko Ozawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced retinal function in amyloid precursor protein-over-expressing transgenic mice via attenuating glutamate-N-methyl-d-aspartate receptor signaling

(2008) Masamitsu Shimazawa et al.   JOURNAL OF NEUROCHEMISTRY

Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model

(2008) Ryoichi Kimura et al.   NEUROBIOLOGY OF DISEASE

The eye in cerebral malaria: what can it teach us?

(2008) Richard J. Maude et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE