Mutational patterns and their correlation to CHIP-related mutations and age in hematological malignancies

The mutational constraint spectrum quantified from variation in 141,456 humans

(2020) Konrad J. Karczewski et al.   NATURE

Systemic treatment options for advanced biliary tract carcinoma

(2020) Changqing Xie et al.   JOURNAL OF GASTROENTEROLOGY

KRAS inhibition in non–small cell lung cancer: Past failures, new findings and upcoming challenges

(2020) Francesco Passiglia et al.   EUROPEAN JOURNAL OF CANCER

Basket Trials for Intractable Cancer

(2019) Bao-Dong Qin et al.   Frontiers in Oncology

A Novel Machine Learning Based in silico Pathogenicity Predictor for Missense Variants in a Hematological Setting

(2019) Stephan Hutter et al.   BLOOD

Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations

(2018) Andreas Agathangelidis et al.   HAEMATOLOGICA

Prognostic significance of interphase FISH in monoclonal gammopathy of undetermined significance

(2018) Arjun Lakshman et al.   LEUKEMIA

Concise Review: Age-Related Clonal Hematopoiesis: Stem Cells Tempting the Devil

(2018) Lambert Busque et al.   STEM CELLS

Aging and the rise of somatic cancer-associated mutations in normal tissues

(2018) Rosa Ana Risques et al.   PLoS Genetics

Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations

(2018) Andreas Agathangelidis et al.   HAEMATOLOGICA

Preleukaemic clonal haemopoiesis and risk of therapy-related myeloid neoplasms: a case-control study

(2017) Koichi Takahashi et al.   LANCET ONCOLOGY

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease

(2017) Siddhartha Jaiswal et al.   NEW ENGLAND JOURNAL OF MEDICINE

ClinVar: improving access to variant interpretations and supporting evidence

(2017) Melissa J Landrum et al.   NUCLEIC ACIDS RESEARCH

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

(2016) D. A. Arber et al.   BLOOD

Extensive sequencing of seven human genomes to characterize benchmark reference materials

(2016) Justin M. Zook et al.   Scientific Data

Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes

(2015) D. P. Steensma et al.   BLOOD

Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation

(2015) Michael R. Green et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

(2014) Siddhartha Jaiswal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prevalence and clinical significance of the MYD88 (L265P) somatic mutation in Waldenstrom's macroglobulinemia and related lymphoid neoplasms

(2013) M. Varettoni et al.   BLOOD

Detecting false-positive signals in exome sequencing

(2012) Karin V. Fuentes Fajardo et al.   HUMAN MUTATION

A review and appraisal of the DNA damage theory of ageing

(2011) Alex A. Freitas et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

BRAFMutations in Hairy-Cell Leukemia

(2011) Enrico Tiacci et al.   NEW ENGLAND JOURNAL OF MEDICINE

PHF6 mutations in adult acute myeloid leukemia

(2010) P Van Vlierberghe et al.   LEUKEMIA

PHF6 mutations in T-cell acute lymphoblastic leukemia

(2010) Pieter Van Vlierberghe et al.   NATURE GENETICS