Multifaceted pathomolecular mechanism of a VWF large deletion involved in the pathogenesis of severe VWD

Chemotaxis and swarming in differentiated HL-60 neutrophil-like cells

(2021) Kehinde Adebayo Babatunde et al.   Scientific Reports

von Willebrand factor propeptide missense variants affect anterograde transport to Golgi resulting in ER retention

(2021) Hamideh Yadegari et al.   HUMAN MUTATION

Characterization of large in-frame von Willebrand factor deletions highlights differing pathogenic mechanisms

(2020) Ashley Cartwright et al.   Blood Advances

Standardization of methods to quantify and culture endothelial colony‐forming cells derived from peripheral blood

(2019) David M. Smadja et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

von Willebrand factor regulation of blood vessel formation

(2018) Anna M. Randi et al.   BLOOD

Tuning the endothelial response: differential release of exocytic cargos from Weibel-Palade Bodies

(2018) Thomas D. Nightingale et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity

(2018) Laura L. Swystun et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic regulation of plasma von Willebrand factor levels in health and disease

(2018) Laura L. Swystun et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor

(2018) Emma-Ruoqi Xu et al.   BLOOD

von Willebrand factor clearance - biological mechanisms and clinical significance

(2018) Jamie M. O'Sullivan et al.   BRITISH JOURNAL OF HAEMATOLOGY

Exocytosis of Weibel–Palade bodies: how to unpack a vascular emergency kit

(2018) M. Schillemans et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

Weibel−Palade bodies at a glance

(2017) Jessica J. McCormack et al.   JOURNAL OF CELL SCIENCE

von Willebrand factor and inflammation

(2017) C. Kawecki et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Von Willebrand’s Disease

(2017)   NEW ENGLAND JOURNAL OF MEDICINE

Von Willebrand disease mutation spectrum and associated mutation mechanisms

(2017) Annika de Jong et al.   THROMBOSIS RESEARCH

Characterization of aberrant splicing of von Willebrand factor in von Willebrand disease: an underrecognized mechanism

(2016) L. Hawke et al.   BLOOD

Intron retention resulting from a silent mutation in the VWF gene that structurally influences the 5' splice site

(2016) H. Yadegari et al.   BLOOD

Pharmacokinetics, efficacy, and safety of a plasma-derived VWF/FVIII concentrate (VONCENTO) for on-demand and prophylactic treatment in patients with von Willebrand disease (SWIFT-VWD study)

(2016) Toshko J. Lissitchkov et al.   BLOOD COAGULATION & FIBRINOLYSIS

Tie1 controls angiopoietin function in vascular remodeling and inflammation

(2016) Emilia A. Korhonen et al.   JOURNAL OF CLINICAL INVESTIGATION

miARma-Seq: a comprehensive tool for miRNA, mRNA and circRNA analysis

(2016) Eduardo Andrés-León et al.   Scientific Reports

A genetically-engineered von Willebrand disease type 2B mouse model displays defects in hemostasis and inflammation

(2016) Frédéric Adam et al.   Scientific Reports

von Willebrand factor biosynthesis, secretion, and clearance: connecting the far ends

(2015) P. J. Lenting et al.   BLOOD

Local VE-cadherin mechanotransduction triggers long-ranged remodeling of endothelial monolayers

(2015) A. K. Barry et al.   JOURNAL OF CELL SCIENCE

Angiogenic characteristics of blood outgrowth endothelial cells from patients with von Willebrand disease

(2015) D. J. Groeneveld et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Endothelial destabilization by angiopoietin-2 via integrin β1 activation

(2015) Laura Hakanpaa et al.   Nature Communications

STXBP1 promotes Weibel-Palade body exocytosis through its interaction with the Rab27A effector Slp4-a

(2014) D. van Breevoort et al.   BLOOD

Endothelial permeability and VE-cadherin

(2014) Julie Gavard   Cell Adhesion & Migration

Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease

(2013) J.-W. Wang et al.   BLOOD

The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels

(2013) N. Rydz et al.   BLOOD

Cellular and molecular basis of von Willebrand disease: studies on blood outgrowth endothelial cells

(2013) R. D. Starke et al.   BLOOD

VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity

(2013) Monica Giannotta et al.   DEVELOPMENTAL CELL

Insights into pathological mechanisms of missense mutations in C-terminal domains of von Willebrand factor causing qualitative or quantitative von Willebrand disease

(2013) H. Yadegari et al.   HAEMATOLOGICA

Blocking Von Willebrand Factor for Treatment of Cutaneous Inflammation

(2013) Carina Hillgruber et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Differential regulation of angiopoietin 1 and angiopoietin 2 during dengue virus infection of human umbilical vein endothelial cells: implications for endothelial hyperpermeability

(2013) Siew Pei Ong et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

The Complex Role of Angiopoietin-2 in the Angiopoietin-Tie Signaling Pathway

(2013) G. Thurston et al.   Cold Spring Harbor Perspectives in Medicine

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

VON WILLEBRAND FACTOR, ANGIODYSPLASIA AND ANGIOGENESIS

(2013) Anna M. Randi et al.   Mediterranean Journal of Hematology and Infectious Diseases

von Willebrand Factor: More Than a Regulator of Hemostasis and Thrombosis

(2012) Gui-Ping Luo et al.   ACTA HAEMATOLOGICA

Sequence and structure relationships within von Willebrand factor

(2012) Y.-F. Zhou et al.   BLOOD

Macrophage LRP1 contributes to the clearance of von Willebrand factor

(2012) G. Rastegarlari et al.   BLOOD

Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling

(2012) Moritz Felcht et al.   JOURNAL OF CLINICAL INVESTIGATION

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Establishment of outgrowth endothelial cells from peripheral blood

(2012) Javier Martin-Ramirez et al.   Nature Protocols

Mutation distribution in the von Willebrand factor gene related to the different von Willebrand disease (VWD) types in a cohort of VWD patients

(2012) Hamideh Yadegari et al.   THROMBOSIS AND HAEMOSTASIS

Functional architecture of Weibel-Palade bodies

(2011) K. M. Valentijn et al.   BLOOD

Angiopoietin-2 promotes myeloid cell infiltration in a  2-integrin-dependent manner

(2011) A. Scholz et al.   BLOOD

Intracellular Storage and Regulated Secretion of Von Willebrand Factor in Quantitative Von Willebrand Disease

(2011) Jiong-Wei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Large deletions identified in patients with von Willebrand disease using multiple ligation-dependent probe amplification

(2011) H. YADEGARI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Overlap extension PCR cloning: a simple and reliable way to create recombinant plasmids

(2010) Anton Bryksin et al.   BIOTECHNIQUES

The dominant-negative von Willebrand factor gene deletion p.P1127_C1948delinsR: molecular mechanism and modulation

(2010) C. Casari et al.   BLOOD

Endothelial von Willebrand factor regulates angiogenesis

(2010) R. D. Starke et al.   BLOOD

ISTH/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders

(2010) F. RODEGHIERO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Contrasting Actions of Selective Inhibitors of Angiopoietin-1 and Angiopoietin-2 on the Normalization of Tumor Blood Vessels

(2009) Beverly L. Falcón et al.   AMERICAN JOURNAL OF PATHOLOGY

Angiopoietin-2 Exocytosis Is Stimulated by Sphingosine-1-Phosphate in Human Blood and Lymphatic Endothelial Cells

(2008) Cholsoon Jang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Selective release of molecules from Weibel-Palade bodies during a lingering kiss

(2008) V. Babich et al.   BLOOD

Clearance of von Willebrand factor

(2008) Cécile V. Denis et al.   THROMBOSIS AND HAEMOSTASIS