Article
Nutrition & Dietetics
Xinrui Yao, Na Zuo, Wenzheng Guan, Lingjie Fu, Shuyi Jiang, Jiao Jiao, Xiuxia Wang
Summary: This study investigated the relationship between two enterotypes and blood trace elements in infertile women. It found significant differences in copper, zinc, magnesium, and iron levels between Prevotella enterotype and Bacteroides enterotype in infertile participants. Prevotella enterotype was associated with low iron levels in the obesity population, while Bacteroides enterotype was associated with high iron levels in the lean/normal and overweight populations.
Article
Biochemistry & Molecular Biology
Lu Gong, Qing Yang, Chang-Wen-Bo Liu, Xu Wang, Hao-Long Zeng
Summary: Exposure to toxic trace elements and deficiencies of essential elements during pregnancy can lead to birth complications. A study in Wuhan, China, compared the levels of various elements in the whole blood of pregnant women and non-pregnant women, finding significant differences in some elements between the two groups. This research also identified variations in levels of certain elements among different gestational ages and maternal ages.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Article
Health Care Sciences & Services
Miren Begona Zuberoa, Sabrina Llop, Amaia Irizar, Mario Murcia, Amaia Molinuevo, Ferran Ballester, Michael Levi, Manuel Lozano, Mikel Ayerdi, Loreto Santa-Marina
Summary: This study describes the serum levels of calcium, copper, selenium, magnesium, iron, and zinc in women in the first trimester of pregnancy and evaluates their relationship with maternal socio-demographic characteristics and dietary variables. The results indicate that the concentrations of these elements are within the normal range and are associated with different socio-demographic characteristics and dietary variables.
Article
Infectious Diseases
Selena Alonso, Marta Vidal, Gemma Ruiz-Olalla, Raquel Gonzalez, Chenjerai Jairoce, M. Nelia Manaca, Miquel Vazquez-Santiago, Reyes Balcells, Anifa Vala, Maria Ruperez, Pau Cistero, Laura Fuente-Soro, Evelina Angov, Ross L. Coppel, Benoit Gamain, David Cavanagh, James G. Beeson, Arsenio Nhacolo, Esperanca Sevene, John J. Aponte, Eusebio Macete, Ruth Aguilar, Alfredo Mayor, Clara Menendez, Carlota Dobano, Gemma Moncunill
Summary: This study aimed to evaluate the impact of maternal HIV infection and placental malaria on the cord blood levels of IgG and IgG subclasses, with findings showing that maternal antibody levels were the main determinants of cord antibody levels. HIV infection and placental malaria were found to reduce the transfer and cord levels of antibodies.
JOURNAL OF INFECTION
(2021)
Article
Nutrition & Dietetics
Lilly Johanna Schmalbrock, Gregor Weiss, Eddy Rijntjes, Nina Reinschissler, Qian Sun, Michael Schenk, Lutz Schomburg
Summary: The study examined the relationship between trace elements and female subfertility influenced by assisted reproductive technologies, revealing a direct connection between TE in serum and follicular fluid, as well as high variability between follicular fluid samples from the same woman. The results suggest that TE assessment may aid in optimal oocyte selection and impact the success of ART.
Article
Environmental Sciences
Isis Baro-Camarasa, Ana Judith Marmolejo-Rodriguez, Antonio Cobelo-Garcia, Marta D. Palacios, Daniela Alejandra Murillo-Cisneros, Felipe Galvan-Magana
Summary: This study investigated the transfer of essential and non-essential trace elements from a pregnant Munk's pygmy devil ray female to its embryo. The results showed elevated concentrations of arsenic in both the pregnant female and the embryo tissues, while higher levels of cadmium, vanadium, uranium, and silver were found in the pregnant female's liver compared to the embryo tissue. This study provides insights into the maternal transfer of trace elements in these species and their reproductive strategy.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Nutrition & Dietetics
Min Wang, Xiaozhuang Zhang, Yanhong Zhao, Yubin Zhang, Yan Lin, Meifang Xiao, Ling Li
Summary: This study reveals differences in the prevalence of iron-deficiency anemia (IDA) among carriers of different thalassemia genotypes. In high-risk areas, the possibility of IDA should be fully considered in pregnant women with alpha-thalassemia silent or minor genotypes, and iron supplementation should be monitored dynamically. Pregnant women with beta-thalassemia minor genotypes have a lower incidence of IDA.
FRONTIERS IN NUTRITION
(2022)
Article
Medicine, General & Internal
Somphavanh Somlor, Ludovic Brossault, Marc Grandadam
Summary: The study evaluated the performance of three prototype assays developed for the VIDAS(R) automated platform in detecting dengue virus infection. The results showed that the VIDAS(R) NS1 assay had the best overall agreement with competitor ELISA, while the IgM and IgG assays had moderate agreement.
Review
Nutrition & Dietetics
Rui Lei, Xiao Liu, Jinfeng Wu
Summary: Trace elements such as copper, manganese, selenium, zinc, and iron are associated with the occurrence and development of melanoma in humans. They affect melanoma through mechanisms like oxidative stress and the MAPK pathway. The literature suggests promising prospects for the role of trace elements in the pathogenesis and treatment of melanoma.
Article
Environmental Sciences
Celia Rodriguez-Perez, Celia Gomez-Pena, Francisco M. Perez-Carrascosa, Petra Vrhovnik, Ruth Echeverria, Inmaculada Salcedo-Bellido, Vicente Mustieles, Fiket Zeljka, Juan Pedro Arrebola
Summary: This study revealed that adipose tissue concentrations of chromium, iron, and copper were associated with the incidence of T2DM over a 16-year follow-up period. Additionally, vanadium and zinc concentrations were positively correlated with pancreatic cell function, while selenium showed an inverse association. These findings suggest that certain trace elements in adipose tissue may play a role in the development of T2DM and have potential implications for identifying individuals at risk.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Dan Yang, Jiajia Wu, Lingbin Yan, Lifei Yu, Jingchun Liu, Chongling Yan
Summary: This study compared the sediment characteristics between halophyte plants habitat and mudflats in intertidal habitats, showing higher concentrations of trace elements in sediment associated with S. alterniflora in Beihai. Variations in magnetic minerals accumulation in different sites explained the differences in sediment-bound As, Hg, Sb, Cd and Sc between S. alterniflora and mudflats.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Multidisciplinary Sciences
T. Clendenen, S. Hu, Y. Afanasyeva, M. Askenazi, K. L. Koenig, T. Hulett, M. Liu, S. Liu, F. Wu, A. Zeleniuch-Jacquotte, Y. Chen
Summary: Autoantibodies in healthy individuals were studied for their reproducibility and stability over time. The research showed that most autoantibodies had good reproducibility in the lab and over a one-year period. This study provides important insights for the use of autoantibodies as markers of disease.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Multidisciplinary
Jia Lv, Yan-ling Li, Wen-qiang Ren, Rong Li, Jian-rong Chen, Chao Bao, Zhi-ping Du, Shun Feng, Ling Gu, Hui Gao, Kai-yong Liu, Lin-sheng Yang, Xiu-de Li, Hong-juan Cao, Fang-biao Tao, Jie Sheng, Qu-nan Wang
Summary: This study found that high concentrations of strontium (Sr) and barium (Ba) were risk factors for depressive symptoms in elderly Chinese individuals, especially in women.
ENVIRONMENTAL CHEMISTRY LETTERS
(2021)
Article
Multidisciplinary Sciences
Jean-David Morel, Lucie Sauzeat, Ludger J. E. Goeminne, Pooja Jha, Evan Williams, Riekelt H. Houtkooper, Ruedi Aebersold, Johan Auwerx, Vincent Balter
Summary: The metallome is often overlooked in mammals, but it plays a crucial role in cell functioning. In this study, the authors analyze the metallome and copper and zinc isotope compositions in aging mice and identify organ-specific, age-dependent, and isotopically-typified networks of interactions that are associated with clinical and molecular traits. The findings shed light on the importance of the metallome as an overlooked omic layer and provide insights into potential manipulation of cellular processes.
NATURE COMMUNICATIONS
(2022)
Article
Biology
Isabella Bracchi, Juliana Guimaraes, Catarina Rodrigues, Rui Azevedo, Claudia Matta Coelho, Catia Pinheiro, Juliana Morais, Ines Barreiros-Mota, Virginia Cruz Fernandes, Cristina Delerue-Matos, Edgar Pinto, Andre Moreira-Rosario, Luis Filipe Ribeiro de Azevedo, Claudia Camila Dias, Jorge Lima, Ines Sapinho, Carla Ramalho, Conceicao Calhau, Joao Costa Leite, Agostinho Almeida, Diogo Pestana, Elisa Keating
Summary: This study aimed to evaluate the role of essential trace elements in pregnancy health. The findings suggest that high urinary zinc levels increase the risk of pre-eclampsia, but decrease the risk of small head circumference at birth.
Article
Optics
Chenyang Li, Min Guo, Bo Zhang, Chenxi Li, Beilei Yang, Ke Chen
Summary: A miniature single-fiber photoacoustic sensor was designed for the detection of trace amounts of methane gas, utilizing a communal cavity and single fiber to achieve a small cell volume. Experimental results confirmed the practicality of the sensor for detecting methane gas with a minimum detectable limit of 8.4 ppm.
OPTICS AND LASERS IN ENGINEERING
(2022)
Article
Biotechnology & Applied Microbiology
Jingchun Zhou, Jingjing Zhang, Wei Zhang, Zhaoyang Ke, Yanlu Lv, Bo Zhang, Zhifang Liao
Summary: In laryngeal squamous cell carcinoma (LSCC), overexpression of RPN2 promotes cell proliferation, migration, epithelial-mesenchymal transition (EMT), and glycolysis, which are mediated by ROS-induced activation of the PI3K/Akt signaling pathway.
Article
Biochemical Research Methods
Ying Liu, Li Cheng, Guanghui Wang, Jiahui Lv, Yifei He, Pan-Lin Shao, Ruibin Hu, Hongjun Xiao, Jiahu Tang, Dan Niu, Jingkai Yang, Zhongrong Tang, Ziyi Xu, Yiyi Liu, Yi Li, Kun Song, Benqing Wu, Bo Zhang
Summary: This study reports a novel strategy for efficient recovery of cfDNA and significant removal of genomic DNA contamination during the extraction process. Using this method, over 90% cfDNA recovery rate was achieved with minimal genomic DNA contamination. The application of this method in non-invasive prenatal testing and plasma samples from cancer patients showed improved liquid biopsy precision and reduced sequencing depth.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2022)
Article
Allergy
Cong Li, Bo Zhang, Min Yan, Yueqi Li, Jingyuan Chen, Zhiying Nie, Yuanyuan Guo, Jianbo Shi, Fenghong Chen
Summary: The study identified clinical phenotypes of patients with chronic rhinosinusitis with nasal polyps and asthma and explored their relationship with endoscopic sinus surgery outcomes using cluster analysis. The results showed distinct clusters with unique clinical and inflammatory characteristics and different outcomes after surgery.
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
(2023)
Article
Nutrition & Dietetics
Zhitian Lu, Xudong Li, Min Wang, Xiaojun Zhang, Runxuan Zhuang, Fan Wu, Wenxue Li, Wei Zhu, Bo Zhang
Summary: Nobiletin (NOB), a compound found in citrus peels, has potential lipid-lowering and circadian-enhancing properties. This study showed that NOB can reduce liver triglyceride levels and regulate genes involved in lipid and cholesterol metabolism, independently of the core clock component Bmal1.
Article
Public, Environmental & Occupational Health
Patricia Kamanga, Bo Zhang, William Stones
Summary: In 2012, over 500,000 women were diagnosed with cervical cancer worldwide, with more than 80% occurring in developing nations like Malawi. The incidence of cervical cancer in Malawi is 75.9 per 100,000 women and the mortality rate is 49.8 per 100,000 women. However, immunization and screening rates are low in Malawi, with coverage as low as 9% and 15% respectively. This study aims to uncover factors contributing to the low utilization of cervical cancer screening services among women in Lilongwe.
Article
Chemistry, Multidisciplinary
Guanghong Luo, Xing Li, Jihui Lin, Gao Ge, Jiangli Fang, Wangze Song, Gary Guishan Xiao, Bo Zhang, Xiaojun Peng, Yanhong Duo, Ben Zhong Tang
Summary: Ions play a vital role in regulating various biological processes, including tumorigenesis and therapy. The perturbation of ion homeostasis can induce tumor cell death and evoke immune responses. This study prepared a pH-responsive nanoplatform that reprograms the tumor microenvironment and provides antitumor treatment through ion fluctuation.
Article
Chemistry, Analytical
Bo Zhang, Jiachen Jiang, Xian Zhang, Xiao-Song Zhu, Yiwei Shi
Summary: In this paper, a flexible leaky hollowcore fiber (LHCF) photoacoustic (PA) gas sensor based on an embedded acoustic resonant structure is demonstrated. The sensor utilizes a part of a gas conduit as the buffer chamber to construct an equivalent T-type half-open PA cell. The LHCF is installed inside the gas conduit and is replaceable, making the gas sensor flexible to reduce spatial size. The experimental results show a minimum detection limit (MDL) of 21.1 ppb when the lock-in integration time is 200 s, and a normalized noise equivalent absorption coefficient (NNEA) of 5.7 x 10(-9) W/cm(-1) Hz(-1/2).
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Bo Zhang, Jiachen Jiang, Xian Zhang, Yunjiang Jia, Xiaosong Zhu, Yiwei Shi
Summary: A low-frequency flexible resonant photoacoustic (PA) gas sensor using an O-shaped multipass cell is demonstrated, which employs a gradually tapered leaky hollow core fiber (LHCF) that is bent to be an end-to-end structure and put inside a single buffer chamber to form an equivalent H-type acoustic resonator. The proposed PA gas sensor exhibits a first-order longitudinal resonance frequency of 408 Hz and has a minimum detectable limit of 25.8 ppb for acetylene gas.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Jiahui Lv, Ying Liu, Jiahu Tang, Hongjun Xiao, Ruibin Hu, Guanghui Wang, Dan Niu, Pan-Lin Shao, Jingkai Yang, Ziqi Jin, Ziyi Xu, Bo Zhang
Summary: In this study, a new method called MREMB (Membrane-associated RNA Extraction based on Magnetic Beads) was proposed for high-purity mem-RNA isolation from cells. The results showed that MREMB could enrich membrane/secreted protein-coding RNA and amplify the expression differences of related RNAs between cancer and non-neoplastic cells, promising for cancer biomarker discovery.
ANALYTICAL CHEMISTRY
(2023)
Article
Environmental Sciences
Ying Wu, Fulin Zeng, Jinhui Li, Yukang Jiang, Shi Zhao, Luke D. Knibbs, Xiaojun Zhang, Yiding Wang, Qianqian Zhang, Qiong Wang, Qiansheng Hu, Xiaobo Guo, Yumeng Chen, Ganxiang Cao, Jing Wang, Xingfen Yang, Xueqin Wang, Tao Liu, Bo Zhang
Summary: This study investigated the impact of maternal metal exposure on birth weight in a Chinese birth cohort. It found that metal exposure had sex-specific effects on birth weight, with negative associations in girls and positive associations in boys. Cadmium and nickel were associated with higher and lower birth weight in girls, respectively. Thallium concentration also influenced the associations between cadmium, nickel, and birth weight in girls. The findings highlight the complex effects of intrauterine metal exposure on birth weight and the sex heterogeneity in fetal development.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Biochemistry & Molecular Biology
Shanfeng Li, Jialin Wang, Haitao Chen, Jia Hou, Ting Shen, Jing Li, Bin Zhou, Bo Zhang, Hui Liu, De-Ke Jiang
Summary: The genetic variant rs2074890 of TRIM16 is associated with both the risk and prognosis of hepatocellular carcinoma (HCC). This variant affects HCC by regulating the Wnt/β-catenin pathway.
MOLECULAR CARCINOGENESIS
(2023)
Article
Optics
Bo Zhang, Yunjiang Jia, Benlei Zhao, Xiaosong Zhu, Yiwei Shi
Summary: This study demonstrates a photoacoustic gas sensor with a microembedded acoustic resonator for gas leakage detection. The sensor, with its compactness, low-gas consumption, and low cost, has the potential to be a remote gas sensing scheme in fields of environmental protection and industrial process monitoring.
Article
Public, Environmental & Occupational Health
Bo Zhang, Sumeng Wang, Xiyu Yang, Mingyang Chen, Wenhui Ren, Yanping Bao, Youlin Qiao
Summary: This study assessed the knowledge, willingness, and uptake of cervical cancer screening among Chinese females. The findings showed high awareness and willingness, but low overall screening coverage and limited knowledge about cervical cancer. Comprehensive health education should be strengthened through social media platforms and healthcare professionals. Promoting national free cervical cancer screening with high-performance methods is also crucial.
Article
Cell Biology
Shuai Li, Qi Hou, Runjia Wang, Yu Hou, Qiang Wang, Bo Zhang, Cheng Ni, Hui Zheng
Summary: Postoperative cognitive dysfunction (POCD) is a common complication caused by anesthesia and surgery. In this study, we analyzed the gene expression in the hippocampus of aged rats that received sevoflurane anesthesia and identified 226 differentially expressed genes (DEGs). Among the screened hub genes, Agt, Cdkn1a, Ddit4, and Rhob were found to be related to neuronal death process. We confirmed the upregulation of these genes, especially Ddit4, in the hippocampus of aged mice that received sevoflurane anesthesia. Our study focused on DDIT4 as a potential target mediated by NMDAR and may provide a new target for the treatment of sevoflurane neurotoxicity.