Bridging the Gap: The Importance of TUBA1A α-Tubulin in Forming Midline Commissures

The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability

(2020) Johanna Roostalu et al.   eLife

XMAP215 promotes microtubule-F-actin interactions to regulate growth cone microtubules during axon guidance

(2019) Paula G. Slater et al.   JOURNAL OF CELL SCIENCE

Lactacystin: first-in-class proteasome inhibitor still excelling and an exemplar for future antibiotic research

(2019) Satoshi Ōmura et al.   JOURNAL OF ANTIBIOTICS

Effects of α-tubulin acetylation on microtubule structure and stability

(2019) Lisa Eshun-Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential requirements of tubulin genes in mammalian forebrain development

(2019) Elizabeth Bittermann et al.   PLoS Genetics

Windows of opportunity: timing in neurodevelopmental disorders

(2018) Alexandra Krol et al.   CURRENT OPINION IN NEUROBIOLOGY

Brain Tumor promotes axon growth across the midline through interactions with the microtubule stabilizing protein Apc2

(2018) Elise Arbeille et al.   PLoS Genetics

Revisiting Netrin-1: One Who Guides (Axons)

(2018) Nicholas P. Boyer et al.   Frontiers in Cellular Neuroscience

Cue-Polarized Transport of β-actin mRNA Depends on 3′UTR and Microtubules in Live Growth Cones

(2018) Kin-Mei Leung et al.   Frontiers in Cellular Neuroscience

TUBA1A mutations identified in lissencephaly patients dominantly disrupt neuronal migration and impair dynein activity

(2018) Jayne Aiken et al.   HUMAN MOLECULAR GENETICS

An Integrated Cytoskeletal Model of Neurite Outgrowth

(2018) Kyle E. Miller et al.   Frontiers in Cellular Neuroscience

Model for Coordination of Microtubule and Actin Dynamics in Growth Cone Turning

(2018) Erin M. Craig   Frontiers in Cellular Neuroscience

Mutation of the α-tubulin Tuba1a leads to straighter microtubules and perturbs neuronal migration

(2017) Richard Belvindrah et al.   JOURNAL OF CELL BIOLOGY

The formin DAAM is required for coordination of the actin and microtubule cytoskeleton in axonal growth cones

(2017) Szilárd Szikora et al.   JOURNAL OF CELL SCIENCE

The tubulin code at a glance

(2017) Sudarshan Gadadhar et al.   JOURNAL OF CELL SCIENCE

The Microtubule-Associated Protein Tau Mediates the Organization of Microtubules and Their Dynamic Exploration of Actin-Rich Lamellipodia and Filopodia of Cortical Growth Cones

(2017) Sayantanee Biswas et al.   JOURNAL OF NEUROSCIENCE

Dynamic mRNA Transport and Local Translation in Radial Glial Progenitors of the Developing Brain

(2016) Louis-Jan Pilaz et al.   CURRENT BIOLOGY

Stability properties of neuronal microtubules

(2016) Peter W. Baas et al.   Cytoskeleton

Novel α-tubulin mutation disrupts neural development and tubulin proteostasis

(2016) M. Gartz Hanson et al.   DEVELOPMENTAL BIOLOGY

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

Affinity purification and characterization of functional tubulin from cell suspension cultures of Arabidopsis and tobacco

(2016) Takashi Hotta et al.   PLANT PHYSIOLOGY

In vitro characterization of neurite extension using induced pluripotent stem cells derived from lissencephaly patients with TUBA1A missense mutations

(2016) Yohei Bamba et al.   Molecular Brain

Recognizable cerebellar dysplasia associated with mutations in multiple tubulin genes

(2015) Renske Oegema et al.   HUMAN MOLECULAR GENETICS

Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones

(2015) Michael Piper et al.   Neural Development

Building the Neuronal Microtubule Cytoskeleton

(2015) Lukas C. Kapitein et al.   NEURON

ThunderSTORM: a comprehensive ImageJ plug-in for PALM and STORM data analysis and super-resolution imaging

(2014) Martin Ovesný et al.   BIOINFORMATICS

Six Subgroups and Extensive Recent Duplications Characterize the Evolution of the Eukaryotic Tubulin Protein Family

(2014) Peggy Findeisen et al.   Genome Biology and Evolution

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Regulation of microtubule motors by tubulin isotypes and post-translational modifications

(2014) Minhajuddin Sirajuddin et al.   NATURE CELL BIOLOGY

Proteomic identification of the molecular basis of mammalian CNS growth cones

(2014) Michihiro Igarashi   NEUROSCIENCE RESEARCH

Localization events-based sample drift correction for localization microscopy with redundant cross-correlation algorithm

(2014) Yina Wang et al.   OPTICS EXPRESS

Microtubule dynamics in axon guidance

(2014) Guofa Liu et al.   Neuroscience Bulletin

The fidelity of stochastic single-molecule super-resolution reconstructions critically depends upon robust background estimation

(2014) Eelco Hoogendoorn et al.   Scientific Reports

Overlapping cortical malformations and mutations in TUBB2B and TUBA1A

(2013) Thomas D. Cushion et al.   BRAIN

Netrin-DCC Signaling Regulates Corpus Callosum Formation Through Attraction of Pioneering Axons and by Modulating Slit2-Mediated Repulsion

(2013) Thomas Fothergill et al.   CEREBRAL CORTEX

Direct binding of TUBB3 with DCC couples netrin-1 signaling to intracellular microtubule dynamics in axon outgrowth and guidance

(2013) C. Qu et al.   JOURNAL OF CELL SCIENCE

Microtubules in neurons as information carriers

(2013) Erik W. Dent et al.   JOURNAL OF NEUROCHEMISTRY

Zebrafish Embryonic Neurons Transport Messenger RNA to Axons and Growth Cones In Vivo

(2013) M. Baraban et al.   JOURNAL OF NEUROSCIENCE

Microtubule dynamics in neuronal morphogenesis

(2013) A. Sakakibara et al.   Open Biology

Axon Guidance Mechanisms for Establishment of Callosal Connections

(2013) Mitsuaki Nishikimi et al.   NEURAL PLASTICITY

Molecular Basis for Specific Regulation of Neuronal Kinesin-3 Motors by Doublecortin Family Proteins

(2012) Judy S. Liu et al.   MOLECULAR CELL

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Growth Cone MKK7 mRNA Targeting Regulates MAP1b-Dependent Microtubule Bundling to Control Neurite Elongation

(2012) Daniel Feltrin et al.   PLOS BIOLOGY

Design, Overexpression, and Purification of Polymerization-Blocked Yeast αβ-Tubulin Mutants

(2011) Vinu Johnson et al.   BIOCHEMISTRY

Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations

(2011) Max A Tischfield et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Netrin-1-Induced Local  -Actin Synthesis and Growth Cone Guidance Requires Zipcode Binding Protein 1

(2011) K. Welshhans et al.   JOURNAL OF NEUROSCIENCE

MAP1B enhances microtubule assembly rates and axon extension rates in developing neurons

(2011) Stephen R. Tymanskyj et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Human lissencephaly with cerebellar hypoplasia due to mutations in TUBA1A: expansion of the foetal neuropathological phenotype

(2010) Magalie Lecourtois et al.   ACTA NEUROPATHOLOGICA

The Role of Tuba1a in Adult Hippocampal Neurogenesis and the Formation of the Dentate Gyrus

(2010) David A. Keays et al.   DEVELOPMENTAL NEUROSCIENCE

Disease-associated mutations in TUBA1A result in a spectrum of defects in the tubulin folding and heterodimer assembly pathway

(2010) Guoling Tian et al.   HUMAN MOLECULAR GENETICS

TUBA1A mutations cause wide spectrum lissencephaly (smooth brain) and suggest that multiple neuronal migration pathways converge on alpha tubulins

(2010) Ravinesh A. Kumar et al.   HUMAN MOLECULAR GENETICS

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing

(2010) Benjamin Lacroix et al.   JOURNAL OF CELL BIOLOGY

Tubulin post-translational modifications: encoding functions on the neuronal microtubule cytoskeleton

(2010) Carsten Janke et al.   TRENDS IN NEUROSCIENCES

The Growth Cone Cytoskeleton in Axon Outgrowth and Guidance

(2010) E. W. Dent et al.   Cold Spring Harbor Perspectives in Biology

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

(2009) Catherine Creppe et al.   CELL

Control of neuronal polarity and plasticity – a renaissance for microtubules?

(2009) Casper C. Hoogenraad et al.   TRENDS IN CELL BIOLOGY

Subdiffraction-Resolution Fluorescence Imaging with Conventional Fluorescent Probes

(2008) Mike Heilemann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Neuropathological phenotype of a distinct form of lissencephaly associated with mutations in TUBA1A

(2008) Catherine Fallet-Bianco et al.   BRAIN

A Pachygyria-causing α-Tubulin Mutation Results in Inefficient Cycling with CCT and a Deficient Interaction with TBCB

(2008) Guoling Tian et al.   MOLECULAR BIOLOGY OF THE CELL