Abnormal B-Cell and Tfh-Cell Profiles in Patients With Parkinson Disease

The clinical meaning of levodopa equivalent daily dose in Parkinson’s disease

(2021) Charlotte Julien et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Cellular immunology of relapsing multiple sclerosis: interactions, checks, and balances

(2021) Amit Bar-Or et al.   LANCET NEUROLOGY

Pre-treatment T-cell subsets associate with fingolimod treatment responsiveness in multiple sclerosis

(2020) Mahtab Ghadiri et al.   Scientific Reports

Parkinson disease and the immune system — associations, mechanisms and therapeutics

(2020) Eng-King Tan et al.   Nature Reviews Neurology

α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease

(2020) Cecilia S. Lindestam Arlehamn et al.   Nature Communications

Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19

(2020) Matthew C. Woodruff et al.   NATURE IMMUNOLOGY

Imbalance of Circulating Tfh/Tfr Cells in Patients With Parkinson's Disease

(2020) Xiuzhen Zhao et al.   Frontiers in Neurology

Abnormal effector and regulatory T cell subsets in paediatric-onset multiple sclerosis

(2019) Ina Mexhitaj et al.   BRAIN

Non-Antibody-Secreting Functions of B Cells and Their Contribution to Autoimmune Disease

(2019) Andrew Getahun et al.   Annual Review of Cell and Developmental Biology

Naturally occurring antibodies isolated from PD patients inhibit synuclein seeding in vitro and recognize Lewy pathology

(2019) Xinyi Li et al.   ACTA NEUROPATHOLOGICA

Expression of Dopamine Receptors in Immune Regulatory Cells

(2019) Asiel Arce-Sillas et al.   NEUROIMMUNOMODULATION

Regulatory impairment in untreated Parkinson’s disease is not restricted to Tregs: other regulatory populations are also involved

(2019) Diana D. Álvarez-Luquín et al.   Journal of Neuroinflammation

B cell targeted therapies in autoimmune disease

(2019) Jennifer L Barnas et al.   CURRENT OPINION IN IMMUNOLOGY

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

(2019) Mike A Nalls et al.   LANCET NEUROLOGY

Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson’s Disease

(2018) Annika Sommer et al.   Cell Stem Cell

Human T Cell Development, Localization, and Function throughout Life

(2018) Brahma V. Kumar et al.   IMMUNITY

Reassessing B cell contributions in multiple sclerosis

(2018) Rui Li et al.   NATURE IMMUNOLOGY

Dopamine Receptor D5 Signaling Plays a Dual Role in Experimental Autoimmune Encephalomyelitis Potentiating Th17-Mediated Immunity and Favoring Suppressive Activity of Regulatory T-Cells

(2018) Francisco Osorio-Barrios et al.   Frontiers in Cellular Neuroscience

Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus

(2018) Scott A. Jenks et al.   IMMUNITY

B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4+ T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen

(2018) Sheng Hong et al.   IMMUNITY

Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) E. Ray Dorsey et al.   LANCET NEUROLOGY

Human regulatory B cells in health and disease: therapeutic potential

(2017) Claudia Mauri et al.   JOURNAL OF CLINICAL INVESTIGATION

B cell–derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity

(2017) Tanvi Arkatkar et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antibody-Independent Function of Human B Cells Contributes to Antifungal T Cell Responses

(2017) Rui Li et al.   JOURNAL OF IMMUNOLOGY

Reconstitution of the peripheral immune repertoire following withdrawal of fingolimod

(2017) Mahtab Ghadiri et al.   Multiple Sclerosis Journal

TFH-derived dopamine accelerates productive synapses in germinal centres

(2017) Ilenia Papa et al.   NATURE

T cells from patients with Parkinson’s disease recognize α-synuclein peptides

(2017) David Sulzer et al.   NATURE

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

(2017) Diana Chang et al.   NATURE GENETICS

Reconstitution of the peripheral immune repertoire following withdrawal of fingolimod

(2017) Mahtab Ghadiri et al.   Multiple Sclerosis Journal

Elevated Serum α-Synuclein Autoantibodies in Patients with Parkinson’s Disease Relative to Alzheimer’s Disease and Controls

(2017) Ali Shalash et al.   Frontiers in Neurology

Follicular Helper T Cells

(2016) Carola G. Vinuesa et al.   Annual Review of Immunology

Dopamine Receptor D3 Signaling on CD4+T Cells Favors Th1- and Th17-Mediated Immunity

(2016) Francisco Contreras et al.   JOURNAL OF IMMUNOLOGY

Age-Associated B Cells with Proinflammatory Characteristics Are Expanded in a Proportion of Multiple Sclerosis Patients

(2016) Nele Claes et al.   JOURNAL OF IMMUNOLOGY

Dimethyl Fumarate Treatment Mediates an Anti-Inflammatory Shift in B Cell Subsets of Patients with Multiple Sclerosis

(2016) Rui Li et al.   JOURNAL OF IMMUNOLOGY

Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome

(2015) Yiqing Yan et al.   CELL

Plasma apolipoprotein A1 associates with age at onset and motor severity in early Parkinson's disease patients

(2015) Christine R. Swanson et al.   MOVEMENT DISORDERS

Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy

(2015) Rui Li et al.   Science Translational Medicine

MHC class II–dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies

(2013) Nicolas Molnarfi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dopamine Receptor D3 Expressed on CD4+ T Cells Favors Neurodegeneration of Dopaminergic Neurons during Parkinson's Disease

(2013) H. Gonzalez et al.   JOURNAL OF IMMUNOLOGY

B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells

(2012) Tom A. Barr et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reduced T helper and B lymphocytes in Parkinson's disease

(2012) Claire H. Stevens et al.   JOURNAL OF NEUROIMMUNOLOGY

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

(2012) Ayumi Yoshizaki et al.   NATURE

Innate Response Activator B Cells Protect Against Microbial Sepsis

(2012) P. J. Rauch et al.   SCIENCE

Parkinson's Disease: Genetics and Pathogenesis

(2011) Joshua M. Shulman et al.   Annual Review of Pathology-Mechanisms of Disease

Decreased expression of B cell related genes in leukocytes of women with Parkinson's disease

(2011) Merav Kedmi et al.   Molecular Neurodegeneration

D1and D2Dopamine Receptor-mediated Inhibition of Activated Normal T Cell Proliferation Is Lost in Jurkat T Leukemic Cells

(2010) Biswarup Basu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

(2009) Amit Bar-Or et al.   ANNALS OF NEUROLOGY

Dopamine released by dendritic cells polarizes Th2 differentiation

(2009) K. Nakano et al.   INTERNATIONAL IMMUNOLOGY

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

(2009) Mark D. Pescovitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I/II randomized, blinded, placebo-controlled, dose-ranging study

(2008) Mark C. Genovese et al.   ARTHRITIS AND RHEUMATISM

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease

(2008) Vanessa Brochard et al.   JOURNAL OF CLINICAL INVESTIGATION