CRISPR/Cas9 Delivery System Engineering for Genome Editing in Therapeutic Applications
出版年份 2021 全文链接
标题
CRISPR/Cas9 Delivery System Engineering for Genome Editing in Therapeutic Applications
作者
关键词
-
出版物
Pharmaceutics
Volume 13, Issue 10, Pages 1649
出版商
MDPI AG
发表日期
2021-10-11
DOI
10.3390/pharmaceutics13101649
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Co-encapsulation of Cas9 mRNA and guide RNA in polyplex micelles enables genome editing in mouse brain
- (2021) Saed Abbasi et al. JOURNAL OF CONTROLLED RELEASE
- All‐In‐One Dendrimer‐Based Lipid Nanoparticles Enable Precise HDR‐Mediated Gene Editing In Vivo
- (2021) Lukas Farbiak et al. ADVANCED MATERIALS
- Traceable Nano‐Biohybrid Complexes by One‐Step Synthesis as CRISPR‐Chem Vectors for Neurodegenerative Diseases Synergistic Treatment
- (2021) Jie Shen et al. ADVANCED MATERIALS
- Rational Design of Poly(disulfide)s as a Universal Platform for Delivery of CRISPR-Cas9 Machineries toward Therapeutic Genome Editing
- (2021) Jiajing Guo et al. ACS Central Science
- Efficient Peptide-Mediated In Vitro Delivery of Cas9 RNP
- (2021) Oskar Gustafsson et al. Pharmaceutics
- Cas9 conjugate complex delivering donor DNA for efficient gene editing by homology-directed repair
- (2021) Yoo Kyung Kang et al. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
- Enhanced lysosome escape mediated by 1,2-dicarboxylic-cyclohexene anhydride-modified poly-L-lysine dendrimer as a gene delivery system
- (2020) Jianmin Shen et al. Asian Journal of Pharmaceutical Sciences
- CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors
- (2020) Dan Wang et al. CELL
- Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
- (2020) Qiang Cheng et al. Nature Nanotechnology
- pH-responsive strontium nanoparticles for targeted gene therapy against mammary carcinoma cells
- (2020) Athirah Bakhtiar et al. Asian Journal of Pharmaceutical Sciences
- Lecithin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes
- (2019) Eun Yi Cho et al. JOURNAL OF NANOBIOTECHNOLOGY
- Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy
- (2019) Christopher E. Nelson et al. NATURE MEDICINE
- Delivery Aspects of CRISPR/Cas for in Vivo Genome Editing
- (2019) Danny Wilbie et al. ACCOUNTS OF CHEMICAL RESEARCH
- Engineered targeting tLyp-1 exosomes as gene therapy vectors for efficient delivery of siRNA into lung cancer cells
- (2019) Jing Bai et al. Asian Journal of Pharmaceutical Sciences
- Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles
- (2019) Ji Liu et al. ADVANCED MATERIALS
- A boronic acid–rich dendrimer with robust and unprecedented efficiency for cytosolic protein delivery and CRISPR-Cas9 gene editing
- (2019) Chongyi Liu et al. Science Advances
- A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing
- (2019) Guojun Chen et al. Nature Nanotechnology
- Prevalence of Anti-Adeno-Associated Virus Immune Responses in International Cohorts of Healthy Donors
- (2019) Anita Kruzik et al. Molecular Therapy-Methods & Clinical Development
- Tumor microenvironment responsive drug delivery systems
- (2019) Qunye He et al. Asian Journal of Pharmaceutical Sciences
- Rational designs of in vivo CRISPR-Cas delivery systems
- (2019) Cong-Fei Xu et al. ADVANCED DRUG DELIVERY REVIEWS
- Macrophage-Specific in Vivo Gene Editing Using Cationic Lipid-Assisted Polymeric Nanoparticles
- (2018) Ying-Li Luo et al. ACS Nano
- Simple In Vivo Gene Editing via Direct Self-Assembly of Cas9 Ribonucleoprotein Complexes for Cancer Treatment
- (2018) Seung Min Kim et al. ACS Nano
- Thermo-triggered Release of CRISPR-Cas9 System by Lipid-Encapsulated Gold Nanoparticles for Tumor Therapy
- (2018) Peng Wang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Dual-Targeting Delivery System for Effective Genome Editing and In Situ Detecting Related Protein Expression in Edited Cells
- (2018) Bo-Ya Liu et al. BIOMACROMOLECULES
- Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities
- (2018) Ling Li et al. BIOMATERIALS
- Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing
- (2018) Romain Rouet et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Efficient generation of targeted large insertions by microinjection into two-cell-stage mouse embryos
- (2018) Bin Gu et al. NATURE BIOTECHNOLOGY
- Efficient RNA drug delivery using red blood cell extracellular vesicles
- (2018) Waqas Muhammad Usman et al. Nature Communications
- A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing
- (2018) Jonathan D. Finn et al. Cell Reports
- Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification
- (2018) Sriram Vaidyanathan et al. Molecular Therapy-Nucleic Acids
- Exosome-Liposome Hybrid Nanoparticles Deliver CRISPR/Cas9 System in MSCs
- (2018) Yao Lin et al. Advanced Science
- Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours
- (2018) Bumwhee Lee et al. Nature Biomedical Engineering
- Key role of the REC lobe during CRISPR–Cas9 activation by ‘sensing’, ‘regulating’, and ‘locking’ the catalytic HNH domain
- (2018) Giulia Palermo et al. QUARTERLY REVIEWS OF BIOPHYSICS
- The IS2 Element Improves Transcription Efficiency of Integration-Deficient Lentiviral Vector Episomes
- (2018) Sabina Sánchez-Hernández et al. Molecular Therapy-Nucleic Acids
- Potent Protein Delivery into Mammalian Cells via a Supercharged Polypeptide
- (2018) Jun Yin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- In Vitro and in Vivo RNA Inhibition by CD9-HuR Functionalized Exosomes Encapsulated with miRNA or CRISPR/dCas9
- (2018) Zhelong Li et al. NANO LETTERS
- Treatment of a metabolic liver disease by in vivo genome base editing in adult mice
- (2018) Lukas Villiger et al. NATURE MEDICINE
- Redox-sensitive, PEG-shielded carboxymethyl PEI nanogels silencing MicroRNA-21, sensitizes resistant ovarian cancer cells to cisplatin
- (2018) Sanaz Javanmardi et al. Asian Journal of Pharmaceutical Sciences
- Cancer-derived exosomes as a delivery platform of CRISPR/Cas9 confer cancer cell tropism-dependent targeting
- (2017) Seung Min Kim et al. JOURNAL OF CONTROLLED RELEASE
- Endosomal Escape and Delivery of CRISPR/Cas9 Genome Editing Machinery Enabled by Nanoscale Zeolitic Imidazolate Framework
- (2017) Shahad K. Alsaiari et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
- (2017) Nicole M. Gaudelli et al. NATURE
- Highly efficient RNA-guided base editing in mouse embryos
- (2017) Kyoungmi Kim et al. NATURE BIOTECHNOLOGY
- Selective disruption of an oncogenic mutant allele by CRISPR/Cas9 induces efficient tumor regression
- (2017) Taeyoung Koo et al. NUCLEIC ACIDS RESEARCH
- Targeted activation of diverse CRISPR-Cas systems for mammalian genome editing via proximal CRISPR targeting
- (2017) Fuqiang Chen et al. Nature Communications
- The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes
- (2017) Nicolas Merienne et al. Cell Reports
- Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair
- (2017) Kunwoo Lee et al. Nature Biomedical Engineering
- Artificial Virus Delivers CRISPR-Cas9 System for Genome Editing of Cells in Mice
- (2016) Ling Li et al. ACS Nano
- CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice
- (2016) Li Xu et al. MOLECULAR THERAPY
- Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
- (2016) Alexis C. Komor et al. NATURE
- Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing
- (2015) Wujin Sun et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors
- (2015) Jianbin Wang et al. NATURE BIOTECHNOLOGY
- Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition
- (2015) Benjamin P Kleinstiver et al. NATURE BIOTECHNOLOGY
- Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
- (2015) Kathrin Schumann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
- (2014) Randall J. Platt et al. CELL
- Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells
- (2014) Yuxuan Wu et al. CELL RESEARCH
- Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system
- (2013) Albert W Cheng et al. CELL RESEARCH
- CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
- (2013) Prashant Mali et al. NATURE BIOTECHNOLOGY
- DNA targeting specificity of RNA-guided Cas9 nucleases
- (2013) Patrick D Hsu et al. NATURE BIOTECHNOLOGY
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Site-specific integration and tailoring of cassette design for sustainable gene transfer
- (2011) Angelo Lombardo et al. NATURE METHODS
- Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L
- (2011) B. R. Anderson et al. NUCLEIC ACIDS RESEARCH
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