4.6 Review

Ruptured Hepatocellular Carcinoma: Current Status of Research

期刊

FRONTIERS IN ONCOLOGY
卷 12, 期 -, 页码 -

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fonc.2022.848903

关键词

hepatocellular carcinoma; spontaneous rupture; mechanism; diagnosis; treatment

类别

资金

  1. Natural Science Foundation of Hubei Province [2019CFB433]
  2. Hengrui Hepatobiliary and Pancreatic Malignant Tumor Research Fund-Youth Research Fund [CXPJJH11800001-2018306]
  3. Key project of science and technology in Hubei Province [2018ACA137]
  4. General Project of Health Commission of Hubei Province [WJ2021M108]

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Ruptured hepatocellular carcinoma (rHCC) is a rare and life-threatening condition. The incidence is increasing, especially in Asia. Abdominal pain is the most common symptom, and there are various treatments available. Aggressive treatment can lead to improved prognosis for rHCC patients.
BackgroundRuptured hepatocellular carcinoma (rHCC) is considered a rare and life-threatening manifestation; when it happens, it often requires acute and positive intervention. At present, the mechanism of rHCC development is gradually being understood while there are many kinds of rHCC treatment. From our clinical observation, the prognosis of rHCC patients is not as poor as it is currently believed. It may not be appropriate to include all patients with rHCC in T4. Main BodyThe incidence of ruptured hepatocellular carcinoma is now rising. Especially in the Asian region, it can even reach 10% - 15%. The most common symptom of HCC rupture is abdominal pain, and there are now a variety of treatments for hepatocellular carcinoma rupture. With aggressive treatment, rHCC patients can also achieve a better prognosis. The patient's condition varies on admission, so the treatment methods will also be different. It is critical to identify prognostic factors simultaneously, and rHCC can be effectively managed by focusing on important prognostic factors. ConclusionA review was carried out to analyze diagnosis, mechanism, treatment, and prognostic risk factors on this disease condition during the current situation; it is hoped that it will provide better guidance for clinicians. Moreover, patients with rHCC were managed hierarchically to prolong their prognosis.

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