Vitamin B12 and gut-brain homeostasis in the pathophysiology of ischemic stroke

Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes

(2021) Liliana M. Sanmarco et al.   NATURE

Stroke affects intestinal immune cell trafficking to the central nervous system

(2021) David Brea et al.   BRAIN BEHAVIOR AND IMMUNITY

Preliminary analysis of immunoregulatory mechanism of hyperhomocysteinemia‑induced brain injury in Wistar‑Kyoto rats

(2021) Yu Zhang et al.   Experimental and Therapeutic Medicine

Regulatory T cells participate in the recovery of ischemic stroke patients

(2020) María Santamaría-Cadavid et al.   BMC Neurology

B vitamin acquisition by gut commensal bacteria

(2020) Emily E. Putnam et al.   PLoS Pathogens

Vitamin B12 is neuroprotective in experimental pneumococcal meningitis through modulation of hippocampal DNA methylation

(2020) Karina Barbosa de Queiroz et al.   Journal of Neuroinflammation

Distinct Commensal Bacterial Signature in the Gut Is Associated With Acute and Long-Term Protection From Ischemic Stroke

(2020) Corinne Benakis et al.   STROKE

Vitamin B12 Deficiency Alters the Gut Microbiota in a Murine Model of Colitis

(2020) Eberhard Lurz et al.   Frontiers in Nutrition

Gastrointestinal Disorders and Risk of First-Ever Ischemic Stroke

(2020) William H. Roth et al.   STROKE

Dietary Nutrients Involved in One-Carbon Metabolism and Colonic Mucosa-Associated Gut Microbiome in Individuals with an Endoscopically Normal Colon

(2019) Shawn Gurwara et al.   Nutrients

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke

(2019) Geng-Hong Xia et al.   Frontiers in Neurology

Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals

(2019) Pooja R Mandaviya et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Disordered gut microbiota and alterations in metabolic patterns are associated with atrial fibrillation

(2019) Kun Zuo et al.   GigaScience

The impact of vitamin B12 deficiency on infant gut microbiota

(2019) Perran Boran et al.   EUROPEAN JOURNAL OF PEDIATRICS

Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms

(2019) Rebecca Sadler et al.   JOURNAL OF NEUROSCIENCE

Regulating vitamin B12 biosynthesis via thecbiMCbl riboswitch inPropionibacteriumstrain UF1

(2019) Jing Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut Microbiota–Dependent TrimethylamineN-Oxide Predicts Risk of Cardiovascular Events in Patients With Stroke and Is Related to Proinflammatory Monocytes

(2018) Arash Haghikia et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Identification and quantitation of cobalamin and cobalamin analogues in human feces

(2018) Robert H Allen et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Neuropathology of vitamin B12 deficiency in the Cd320−/− mouse

(2018) Kaveri Arora et al.   FASEB JOURNAL

Microbiome–microglia connections via the gut–brain axis

(2018) Reem Abdel-Haq et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery

(2018) Minako Ito et al.   NATURE

Cobalamin (Vitamin B12) Induced a Shift in Microbial Composition and Metabolic Activity in an in vitro Colon Simulation

(2018) Yuanyuan Xu et al.   Frontiers in Microbiology

Sodium butyrate suppresses angiotensin II-induced hypertension by inhibition of renal (pro)renin receptor and intrarenal renin–angiotensin system

(2017) Lei Wang et al.   JOURNAL OF HYPERTENSION

B vitamins in stroke prevention: time to reconsider

(2017) J David Spence et al.   LANCET NEUROLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Beyond gut feelings: how the gut microbiota regulates blood pressure

(2017) Francine Z. Marques et al.   Nature Reviews Cardiology

The gut microbiome in atherosclerotic cardiovascular disease

(2017) Zhuye Jie et al.   Nature Communications

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity

(2016) Melanie Schirmer et al.   CELL

Microbiota Dysbiosis Controls the Neuroinflammatory Response after Stroke

(2016) V. Singh et al.   JOURNAL OF NEUROSCIENCE

Depletion of Cultivatable Gut Microbiota by Broad-Spectrum Antibiotic Pretreatment Worsens Outcome After Murine Stroke

(2016) Katarzyna Winek et al.   STROKE

The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood LipidsNovelty and Significance

(2015) Jingyuan Fu et al.   CIRCULATION RESEARCH

Gut Dysbiosis Is Linked to HypertensionNovelty and Significance

(2015) Tao Yang et al.   HYPERTENSION

Selective modulation of microglia polarization to M2 phenotype for stroke treatment

(2015) Cong-Yuan Xia et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Efficacy of Folic Acid Therapy in Primary Prevention of Stroke Among Adults With Hypertension in China

(2015) Yong Huo et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Role of the Gut Microbiome in Obesity and Diabetes Mellitus

(2015) Gillian M. Barlow et al.   NUTRITION IN CLINICAL PRACTICE

Dietary Gut Microbial Metabolites, Short-chain Fatty Acids, and Host Metabolic Regulation

(2015) Mayu Kasubuchi et al.   Nutrients

A Potential Epigenetic Marker Mediating Serum Folate and Vitamin B12Levels Contributes to the Risk of Ischemic Stroke

(2015) Loo Keat Wei et al.   Biomed Research International

The Treg/Th17 Axis: A Dynamic Balance Regulated by the Gut Microbiome

(2015) Sara Omenetti et al.   Frontiers in Immunology

Vitamin B 12 as a Modulator of Gut Microbial Ecology

(2014) Patrick H. Degnan et al.   Cell Metabolism

Cobamide Structure Depends on Both Lower Ligand Availability and CobT Substrate Specificity

(2013) Terence S. Crofts et al.   CHEMISTRY & BIOLOGY

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS

(2012) Eugene D. Ponomarev et al.   GLIA

Vitamin B12 transport from food to the body's cells—a sophisticated, multistep pathway

(2012) Marianne J. Nielsen et al.   Nature Reviews Gastroenterology & Hepatology

Fetal programming: Maternal nutrition and role of one-carbon metabolism

(2012) Chittaranjan Sakerlal Yajnik et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Effect of B-Vitamin Therapy on Progression of Diabetic Nephropathy

(2010) Andrew A. House et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

(2010) A. M. Thornton et al.   JOURNAL OF IMMUNOLOGY

B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial: a randomised, double-blind, parallel, placebo-controlled trial

(2010)   LANCET NEUROLOGY

Structural basis for receptor recognition of vitamin-B12–intrinsic factor complexes

(2010) Christian Brix Folsted Andersen et al.   NATURE

Diet, gut microbiota and immune responses

(2010) Kendle M Maslowski et al.   NATURE IMMUNOLOGY

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

(2009) Arthur Liesz et al.   NATURE MEDICINE

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL