Pseudogene-mediated DNA demethylation leads to oncogene activation

Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide

(2018) Bee Hui Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recurrently deregulated lncRNAs in hepatocellular carcinoma

(2017) Yang Yang et al.   Nature Communications

DNA demethylation induces SALL4 gene re-expression in subgroups of hepatocellular carcinoma associated with Hepatitis B or C virus infection

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LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration

(2015) Lijun Wang et al.   CELL RESEARCH

DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer

(2015) Callie R. Merry et al.   HUMAN MOLECULAR GENETICS

Dissecting the role of aberrant DNA methylation in human leukaemia

(2015) Giovanni Amabile et al.   Nature Communications

The Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes

(2014) Leng Han et al.   Nature Communications

The long non-coding RNA Dali is an epigenetic regulator of neural differentiation

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DNMT1-interacting RNAs block gene-specific DNA methylation

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Oncofetal Gene SALL4 in Aggressive Hepatocellular Carcinoma

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SALL4 is a new target in endometrial cancer

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Sal-like protein 4 (SALL4), a stem cell biomarker in liver cancers

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Hepatitis B and hepatocellular carcinoma

(2010) Adrian M. Di Bisceglie   HEPATOLOGY

Epidemiology and Management of Hepatocellular Carcinoma

(2010) Ju Dong Yang et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

Sorafenib

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SALL4 is a key regulator of survival and apoptosis in human leukemic cells

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Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

(2008) Toshiaki Watanabe et al.   NATURE

Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells

(2008) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA